PROVENGE

Indicated For

metastatic castrate-resistant prostate cancer, mCRPC

About This Medication

# Dendreon PROVENGE Patient Assistance Program Patient Guide: How to Get PROVENGE (sipuleucel-T) at Low or No Cost PROVENGE (sipuleucel-T) is a personalized immunotherapy treatment for men with certain types of advanced prostate cancer, and the Dendreon PROVENGE Patient Assistance Program can provide it free to eligible uninsured patients.[1][7] This guide explains eligibility, application steps, and support options in simple terms to help you access this treatment. ## About PROVENGE (sipuleucel-T) **PROVENGE** is an autologous cellular immunotherapy, meaning it's made from your own immune cells to treat asymptomatic or minimally symptomatic metastatic castrate-resistant (hormone-refractory) prostate cancer.[1][8] The treatment process involves three cycles: first, your blood cells are collected through a procedure called leukapheresis at a specialized center. These cells are then processed at a Dendreon facility with prostatic acid phosphatase (PAP) and granulocyte-macrophage colony-stimulating factor (GM-CSF) to activate them against cancer cells.[8] About three days later, each dose is infused back into you at your doctor's office or infusion center, taking about 1 hour per infusion followed by 30 minutes of monitoring.[1][8] The full course repeats three times, typically over several weeks.[8] Before starting, get a venous assessment, stay hydrated, eat calcium-rich foods, and wear loose clothing with roll-up sleeves for infusions.[8] PROVENGE is covered by Medicare and most private insurances, with many patients facing low out-of-pocket costs.[1] However, if costs are a barrier, the Patient Assistance Program steps in. ## Who Qualifies for the Program? The program primarily serves **uninsured patients** or those **rendered uninsured** (insurance denies coverage for PROVENGE).[1][7] You must meet these key criteria: - US resident, age 18 or older.[1] - On-label prescription for advanced prostate cancer.[1] - Adjusted gross income (AGI) of **$225,000 or less**.[1][7] Eligibility is determined by Dendreon.[1] There's also a separate **PROvide Commercial Co-pay Program** for commercially insured patients with AGI of **$150,000 or less**, covering up to $6,000 in co-pays, co-insurance, or deductibles over the three treatments.[3] For government insurance like Medicare, independent foundations may cover costs—90% of Medicare fee-for-service patients have supplements with minimal/no out-of-pocket expenses, and 85% pay less than $50.[1] Visit www.fundfinder.org or contact foundations via the program.[1] ## Income Eligibility Breakdown Income limits focus on household adjusted gross income (AGI). Here's a clear table: | Household Type | AGI Limit for Uninsured/Free PROVENGE | AGI Limit for Commercial Co-pay Program | |---------------|---------------------------------------|-----------------------------------------| | Individual/Household | $225,000 or less[1] | $150,000 or less[3] | | Notes | US resident, 18+, on-label use[1] | Covers up to $6,000 over 3 treatments[3] | Larger families may have flexibility, but confirm by phone as specifics aren't detailed.[1][3] Provide your annual household AGI and number of members during application.[3] ## Insurance Requirements - **Uninsured or rendered uninsured**: Eligible for free PROVENGE.[1] - **Commercial insurance**: Use the co-pay program if income-qualified.[3] - **Government insurance (e.g., Medicare)**: Seek foundation help; PROVENGE is Medicare-covered.[1][9] Proof of insurance status is required.[7] Dendreon can help determine if you're 'rendered uninsured'.[1] ## Step-by-Step Application Process 1. **Talk to your doctor**: Get a prescription and discuss if PROVENGE is right. They can start enrollment.[3][8] 2. **Call Dendreon On Call**: Dial **(877) 336-3736** (Option 2 for assistance, Mon-Fri 8am-9pm ET; 24/7 for emergencies).[1][3] This is the main application method—no online form.[7] 3. **Provide details**: Share income, household size, residency, insurance status, and prescription info.[1][3] 4. **Submit documents**: Fax enrollment form to (877) 556-3737 if using doctor's form, or as directed.[3] Required: proof of income (e.g., tax returns), proof of residency, prescription, insurance status.[7] 5. **Eligibility review**: Dendreon assesses quickly; they handle referrals if needed.[1][3] Your doctor’s office can assist throughout.[1] ## Timeline and Delivery Processing time isn't specified, but Dendreon aims to help eligible patients access treatment promptly.[2] The PROVENGE process itself spans weeks: leukapheresis, 3-day processing, infusion—repeated three times.[8] Once approved, PROVENGE is **shipped to your physician's office or directly to you**.[7] Additional support like transportation assistance may be available for leukapheresis.[4][6] ## Alternatives if Denied or Ineligible - **Foundations**: List at provenge.com or www.fundfinder.org for government-insured patients.[1] - **Other programs**: Prescription Hope offers PROVENGE for $60/month (separate service).[5] - **RxAssist**: Check Dendreon listings for updates.[7] - **Appeal or reapply**: Contact Dendreon to discuss denial reasons and refile with more info.[1] - **Transportation**: CancerCare or Dendreon programs.[4][6] ## Important Disclaimer This guide is for informational purposes based on available program details as of latest sources.[1][3] Eligibility can change; **always verify with Dendreon at (877) 336-3736**.[1] Not medical advice—consult your doctor. Dendreon determines final eligibility. Income thresholds are AGI-based and subject to program updates.[1][7] For Medicare, contact your MAC or 1-800-Medicare if claims are denied.[9]

Program information last verified: March 30, 2026