Probuphine

Indicated For

Opioid Use Disorder

About This Medication

# Braeburn Access Program Patient Guide: How to Get Probuphine at Low or No Cost ## About This Program The **Braeburn Access Program** is a manufacturer-sponsored patient assistance program designed to help eligible patients access **Probuphine** (buprenorphine implant) at reduced or no cost. Probuphine is a subdermal implant used for maintenance treatment of opioid dependence in patients who have achieved clinical stability on low-to-moderate doses of buprenorphine.[6] ## What is Probuphine? Probuphine is a **buprenorphine subdermal implant** that provides maintenance treatment for opioid use disorder (OUD). Each kit contains four individual implants, with each implant containing 74.2 mg of buprenorphine (equivalent to 80 mg of buprenorphine hydrochloride).[4] The implants remain in place for six months before removal and replacement.[4] Probuphine is indicated for patients who have: - Achieved and sustained prolonged clinical stability - Been taking a buprenorphine-containing transmucosal product (such as Suboxone or Subutex) for at least 6 months - Been on a stable dose of no more than 8 mg per day of Suboxone or Subutex equivalent[3] The medication should be used as part of a complete treatment program that includes counseling and psychosocial support.[3] ## Who Qualifies? While specific income thresholds for the Braeburn Access Program are not publicly detailed in available materials, the program generally assists patients who: - Have been prescribed Probuphine by a qualified healthcare provider - Meet clinical eligibility criteria for Probuphine treatment - Have insurance or are uninsured/underinsured - Cannot afford the medication cost **Important Note:** Co-pay assistance through the Braeburn Access Program covers the cost of the Probuphine medication itself. However, **the cost of implantation or removal procedures is not eligible for co-pay assistance**.[6] You will need to work with your healthcare provider and insurance to address procedural costs separately. ## Insurance Requirements The Braeburn Access Program works with patients who have various insurance situations: - **Insured patients:** The program may provide co-pay assistance for the Probuphine medication - **Uninsured/underinsured patients:** The program may cover medication costs - **Federal health plan beneficiaries:** Special rules may apply; contact the program directly for details[6] If you have Medicaid or commercial insurance, your plan will typically require **prior authorization** before Probuphine can be dispensed. Your healthcare provider will need to submit clinical documentation showing you meet eligibility criteria, including: - Diagnosis of opioid dependence - Documentation of at least 6 months on a transmucosal buprenorphine product - Proof of dose stability for the past 3 months - Recent urine drug screen results - Confirmation of no recent hospitalizations or emergency room visits related to opioid dependence[2] ## How to Apply ### Step 1: Confirm Clinical Eligibility Work with your prescribing healthcare provider to confirm you meet Probuphine's clinical criteria. Your provider should verify: - You have opioid dependence diagnosis - You've been stable on transmucosal buprenorphine for at least 6 months - Your current dose is 8 mg/day or less - You don't have contraindications (such as pregnancy, moderate-to-severe liver disease, or concurrent methadone use)[2] ### Step 2: Contact the Braeburn Access Program Reach out to the program to begin the enrollment process. You can access enrollment information through the Probuphine REMS program website or contact your healthcare provider's office for assistance. ### Step 3: Complete Enrollment Forms You will need to complete an enrollment form authorizing the program to verify your insurance and assess eligibility for assistance.[6] The form will request: - Your personal and insurance information - Authorization to forward your prescription to a dispensing entity - Acknowledgment that you understand the terms of the assistance program ### Step 4: Insurance Verification The program will perform a preliminary assessment of your insurance coverage and determine your eligibility for co-pay assistance.[6] ### Step 5: Receive Your Medication Once approved, your Probuphine will be dispensed through the program's pharmacy network. ## Important Enrollment Deadline **You must enroll in the Braeburn Access Program no later than 30 days after receiving your Summary of Benefits to qualify for assistance.**[6] ## Processing Timeline and Delivery While specific processing timeframes are not detailed in program materials, typical prior authorization and enrollment processes generally take 5-10 business days. Your healthcare provider can provide more specific timeline information based on your insurance plan. Once approved, Probuphine will be dispensed through established pharmacy channels. Coordinate with your healthcare provider regarding the timing of implantation. ## What If Your Application Is Denied? If you are denied assistance, consider these alternatives: 1. **Review denial reasons:** Contact the program to understand why you were denied and whether you can address any issues 2. **Check state programs:** Some states offer pharmaceutical assistance programs (SPAPs) for low-income residents[7] 3. **Explore other resources:** Visit RxAssist, NeedyMeds, or Partnership for Prescription Assistance for additional patient assistance programs[7] 4. **Discuss with your provider:** Your healthcare provider may have information about other funding sources or alternative treatments 5. **Consider alternative medications:** Discuss with your provider whether other buprenorphine formulations (such as transmucosal products) might be more affordable options ## Important Restrictions - **No duplicate reimbursement:** You and your healthcare provider should not seek reimbursement for any free product received under the program[6] - **Procedural costs not covered:** Implantation and removal costs are your responsibility and must be addressed through your insurance or healthcare provider - **Program-specific assistance only:** This co-pay assistance applies only to Probuphine medication, not to other buprenorphine products ## Disclaimer This guide provides general information about the Braeburn Access Program based on available program materials. Program details, eligibility requirements, and benefits may change. For the most current and complete information, contact the program directly through the Probuphine REMS website or speak with your healthcare provider. This guide is not a substitute for official program documentation or medical advice. Always consult with your healthcare provider regarding your treatment options and eligibility for assistance programs.

Program information last verified: March 30, 2026