Pluvicto

Indicated For

PSMA-positive metastatic castration-resistant prostate cancer (mCRPC)

About This Medication

# Novartis Patient Assistance Program Patient Guide: How to Get Pluvicto (lutetium Lu 177 vipivotide tetraxetan) at Low or No Cost Pluvicto (lutetium Lu 177 vipivotide tetraxetan) is a targeted radioligand therapy used to treat certain types of advanced prostate cancer, specifically prostate-specific membrane antigen-positive (PSMA-positive) metastatic castration-resistant prostate cancer (mCRPC) in patients who have been treated with androgen receptor pathway inhibition (ARPI) and taxane-based chemotherapy. The **Novartis Patient Assistance Program** (also known as the Novartis Patient Assistance Foundation, or NPAF) helps eligible U.S. patients with **limited or no prescription coverage** access Pluvicto at low or no cost if they meet income guidelines.[1][2] ## Who Qualifies for the Program? The program is designed for patients facing financial hardship due to the high cost of Novartis medications like Pluvicto. To qualify, you must: - Reside in the **United States or a U.S. Territory**.[2] - Have a **valid prescription** for Pluvicto from a licensed U.S. healthcare provider treating you on an **outpatient basis**.[1][2] - Have **limited or no prescription insurance coverage** (uninsured, underinsured, or government insurance without adequate prescription benefits).[1][2] - Meet the program's **income guidelines**, which are based on household size and federal poverty level (FPL) thresholds specific to Pluvicto—check exact limits at www.PAP.Novartis.com.[1][2][5] - Provide **proof of income** and insurance details.[1][3] The program does **not** cover patients with insurance tied to alternative funding programs that adjust coverage based on PAP enrollment.[1] ## About Pluvicto **Pluvicto** is an intravenous injection administered in cycles, typically every 6 weeks, under medical supervision. It delivers radiation directly to PSMA-positive cancer cells, helping to slow disease progression and extend life in eligible patients. Treatment requires specialized facilities due to its radioactive nature. Common side effects include fatigue, dry mouth, nausea, decreased blood counts, and kidney issues—discuss risks with your doctor. This assistance program covers the medication cost for those who qualify, but administration fees may still apply.[1][2] ## Income Eligibility Breakdown Income limits vary by medication and household size, often set at **400-500% of the Federal Poverty Level (FPL)** or similar, but **exact thresholds for Pluvicto are listed at PAP.novartis.com**. Use your most recent federal tax return (first two pages) as proof.[1][5] Here's a general example table based on typical Novartis PAP structures (confirm current FPL-adjusted limits online or by calling 800-277-2254): | Household Size | Max Annual Income (Example: ~400% FPL) | |----------------|---------------------------------------| | 1 (Individual) | ~$60,000 | | 2 (Couple) | ~$81,000 | | 3 | ~$102,000 | | 4 | ~$123,000 | | Add per person | ~$21,000 | **Notes**: Household size follows your tax return (Form 1040). Medicare or government insurance may qualify if prescription coverage is limited. Always verify at www.PAP.Novartis.com, as limits change annually.[1][2][5] ## Insurance Requirements You must have **limited or no prescription coverage**. Submit **front and back copies of all insurance cards** (primary, secondary, prescription, Medicare Part D, etc.). The program excludes those with commercial insurance offering adequate coverage or alternative funding-linked plans. If insured, include any **prior authorization (PA) denials or appeals** from your provider.[1][2][3] ## Step-by-Step Application Process 1. **Check Eligibility**: Visit **www.PAP.Novartis.com** or call **800-277-2254** (Mon-Fri, 9am-6pm ET) to confirm Pluvicto coverage and your income fit.[2][5] 2. **Download Forms**: Get the patient application (e.g., NPAF Start Form) from the website or Novartis site.[1][4] 3. **Gather Documents**: - Proof of income (e.g., first 2 pages of 1040 tax return). - Insurance cards (front/back). - Photo ID if requested. - Permission for doctor to share health info.[1][3][5] 4. **Complete Patient Section**: Fill in personal details, household size, income, insurance, and sign authorizations (including caregiver if applicable).[1] 5. **Doctor's Role**: Your healthcare provider (HCP) completes their section, signs, provides prescription, and handles any PA/appeals. Fax HCP section separately if needed.[1][2][3] 6. **Submit**: Fax full form to **1-855-817-2711** or mail to **NPAF, PO Box 2529, Columbus, OH 43216**. Incomplete apps delay or deny processing.[1][5] ## Timeline and Delivery Expect a decision in **about 4 weeks** after submission—track by calling 800-277-2254. If approved, medication ships directly to your doctor's office or infusion center for outpatient administration. Annual eligibility review required; notify if income/insurance changes.[3][5][8] Processing can take several weeks; follow up if no response.[7] ## Alternatives if Denied - **Appeal**: Review denial reasons (e.g., income, insurance) and resubmit corrected docs.[6] - **Other Programs**: Check NeedyMeds, RxAssist, or PAN Foundation for prostate cancer aid. Explore manufacturer copay cards if commercially insured (not via PAP).[5] - **State Assistance**: Contact state Medicaid or pharmaceutical aid programs. - **Call Novartis Support**: 800-277-2254 for guidance.[2] ## Disclaimer This guide is for informational purposes based on available program details as of latest updates. Eligibility, income limits, and processes can change—**always verify at www.PAP.Novartis.com or 800-277-2254**. Not medical/financial advice; consult your doctor and advisor. Novartis may modify/end the program anytime. Word count: ~950.

Program information last verified: March 30, 2026