Pixuvri

Indicated For

DLBCL, relapsed or refractory aggressive Non-Hodgkin B-cell Lymphoma

About This Medication

# Pixuvri (pixantrone) Patient Guide: How to Get Pixuvri at Low or No Cost Pixuvri (pixantrone) is an intravenous chemotherapy medication used as monotherapy for adults with multiply relapsed or refractory aggressive B-cell non-Hodgkin lymphoma (NHL), such as diffuse large B-cell lymphoma (DLBCL), who have failed prior therapies.[1][3][9] This guide explains how to access financial assistance for Pixuvri through manufacturer support from CTI BioPharma or related programs, though specific US patient assistance details are limited; patients should contact the manufacturer directly for the latest options.[1][3] ## About Pixuvri **Pixuvri** is a targeted aza-anthracenedione designed to minimize heart damage compared to traditional anthracyclines while treating hard-to-treat NHL. It is administered as an infusion at 50 mg/m² on days 1, 8, and 15 of a 28-day cycle, up to 6 cycles, with doses adjusted based on blood counts, body surface area, and toxicity.[9] Approved conditionally in the EU for patients who failed 2-3 prior therapies, it offers a first-line monotherapy option for third- or fourth-line use in aggressive B-cell NHL.[3][5][9] It's not established for fifth-line or later use, and caution is advised for liver impairment or low blood counts.[9] Common side effects include bone marrow suppression, nausea, and fatigue; cardiac function must be monitored.[9] Always discuss with your oncologist if Pixuvri fits your treatment plan. ## Who Qualifies for Assistance? CTI BioPharma, the manufacturer of Pixuvri, does not publicly list a dedicated US patient assistance program (PAP) with detailed eligibility on available sources.[1][3][7] However, as a smaller biotech focused on oncology, they likely offer case-by-case support similar to other firms. General oncology assistance programs (e.g., from partners or independents) target: - Uninsured or underinsured patients. - Those with high out-of-pocket costs after insurance. - US residents (programs are US-focused unless noted). Qualification often hinges on income, insurance status, and medical need. Without specifics, contact CTI BioPharma at their listed contacts for personalized guidance.[10] ## Income Eligibility Breakdown No specific income thresholds (e.g., Federal Poverty Level percentages) are published for a Pixuvri PAP.[1-10] Many oncology programs use 400-500% of the Federal Poverty Level (FPL) for households. Here's a general table based on 2026 FPL estimates for illustration (actuals vary; confirm with program): | Household Size | 400% FPL (Approx. Annual Income) | 500% FPL (Approx. Annual Income) | |----------------|---------------------------------|---------------------------------| | Individual | $60,000 | $75,000 | | Couple | $81,000 | $101,000 | | Family of 3 | $102,000 | $127,000 | | Family of 4 | $123,000 | $154,000 | *Notes: Thresholds may adjust for assets, state residency, or expenses. Programs like Pfizer's (for comparison) exclude commercial insurance for free meds but offer co-pay help.[2][8] Pixuvri eligibility unknown; inquire directly.* ## Insurance Requirements Insurance details for Pixuvri PAP are unavailable.[1-10] Typically: - **Uninsured/Publicly Insured** (Medicare Part D, Medicaid): Eligible for free meds in many PAPs, but prior authorization (PA) may be needed first.[2] - **Commercially Insured**: Often ineligible for free drugs but qualify for co-pay cards reducing costs to $0-$25 per infusion (up to $15,000-$25,000/year).[8] Medicare patients excluded from co-pay programs.[2][8] - Enroll in Medicare Prescription Payment Plan if on Part D.[2] Verify coverage with your insurer; Pixuvri may require PA due to specialty status. ## Step-by-Step Application Process 1. **Consult Your Doctor**: Discuss Pixuvri necessity. Obtain prescription and PA if needed.[2] 2. **Contact CTI BioPharma**: Call 206-272-4343 or email [contacts from press].[10] Ask for PAP, compassionate use, or hub program. 3. **Gather Documents**: Likely proof of income (tax returns, pay stubs), insurance denial/statement, ID, prescription.[2] 4. **Apply**: Online, mail, or phone; no specific URL listed.[1-10] 5. **Follow Up**: Track status; expect 2-3 weeks like similar programs.[2] Your oncology team or social worker can assist. ## Timeline and Delivery Processing: 2-3 weeks typical for PAPs; varies.[2] Delivery: Often to doctor's office, pharmacy, or home for infusions.[2] Infusions occur in clinic; medication shipped accordingly. ## Alternatives if Denied - **Independent Hubs**: Pfizer RxPathways connects to 3rd-party aid regardless of insurance.[2] - **Co-Pay Programs**: For commercial insurance, up to $25,000 savings.[8] - **Other Foundations**: Patient Access Network (PAN), CancerCare, or HealthWell for NHL. - **Clinical Trials**: PIX306 Phase 3 ongoing for relapsed NHL.[3][6] - **Generic/Supportive Care**: No biosimilars listed; discuss alternatives with doctor.[ ] ## Disclaimer This guide uses public sources as of 2026; no official CTI PAP details found.[1-10] Eligibility, terms change—contact CTI BioPharma (206-272-4343) or your healthcare provider for current info. Not medical/financial advice; consult professionals. Pixuvri is EU-approved; US status unclear.[1][3] (Word count: 942)

Program information last verified: March 30, 2026