PHESGO

Indicated For

HER2-positive breast cancer

About This Medication

# Genentech Patient Foundation Patient Guide: How to Get PHESGO at Low or No Cost PHESGO (pertuzumab, trastuzumab, and hyaluronidase-zzfx) is a prescription medicine used to treat certain types of breast cancer, such as HER2-positive breast cancer, often in combination with other therapies. The **Genentech Patient Foundation** provides **PHESGO at no cost** to eligible patients who are uninsured, insured without coverage for the medicine, or insured with high out-of-pocket costs after pursuing other assistance.[1][4] ## About PHESGO **PHESGO** is a subcutaneous (under-the-skin) injection that combines two targeted therapies—**pertuzumab** and **trastuzumab**—with hyaluronidase-zzfx, which helps deliver the medicine more easily without needing an IV. It's FDA-approved for adults with HER2-positive breast cancer, either early-stage or metastatic, to help shrink tumors and prevent recurrence when used with chemotherapy like docetaxel.[1][7] Administered by a healthcare provider in a doctor's office, clinic, or hospital, it typically involves loading doses followed by maintenance doses every 3 weeks. Always follow your doctor's instructions, as side effects can include diarrhea, nausea, fatigue, and serious issues like heart problems or infusion reactions—discuss risks with your oncologist.[7] ## Who Qualifies? You may qualify if you: - Have a valid prescription for **PHESGO** for an FDA-approved use. - Live in the US or US Territories. - Are 18+ years old (or have a legally authorized person 18+ managing the program). - Meet income guidelines based on household size and insurance status.[1][4] Separate criteria apply for **uninsured/without coverage** vs. **insured with coverage** patients. Insured patients with coverage must first pursue other assistance options.[4][8] ## Income Eligibility Breakdown Income limits are annual household income before taxes. Add **$25,000 per additional household member** beyond these examples—no maximum household size.[1][4] | Household Size | Uninsured or No Coverage for PHESGO | Insured with Coverage (after other assistance) | |----------------|-------------------------------------|------------------------------------------------| | 1 (Individual) | Under $75,000 | Under $75,000 (OOP max >7.5% of income) | | 2 (Couple) | Under $100,000 | Under $100,000 (OOP max >7.5% of income) | | 3 | Under $125,000 | Under $125,000 (OOP max >7.5% of income) | | 4 | Under $150,000 | Under $150,000 (OOP max >7.5% of income) | | 5+ | Add $25,000 each | Add $25,000 each (OOP max >7.5% of income) | *Examples: Family of 5 uninsured? Limit is $175,000 ($150,000 base + $25,000). Genentech verifies income and may adjust.[1][4]* ## Insurance Requirements - **Uninsured** or **insured without PHESGO coverage**: Eligible if income qualifies.[4] - **Insured with coverage**: Must have out-of-pocket maximum >7.5% of household income, pursue other help first (e.g., co-pay programs), and meet income limits.[4][8] - **Not eligible** if required to apply via third-party Alternative Funding Programs (AFPs) as a coverage prerequisite.[5] - Medicare, Medicaid, or government insurance? Check specifics—program focuses on commercial/private insurance; pursue other resources first.[4][5] ## Step-by-Step Application Process 1. **Confirm eligibility**: Review income, insurance, and residency. Call **(888) 941-3331** (Mon-Fri, 6am-5pm PST) for questions.[1][3] 2. **Complete Patient Consent Form**: Download in English/Spanish from GenentechPatientFoundation.com or phesgo.com. Fill out online, print, or use Quick Enroll.[1][3] 3. **Doctor completes Prescriber Foundation Form**: Inform your doctor's office—they download/submit the English/Spanish form.[2][3] 4. **Gather documents**: Proof of income (tax returns, pay stubs), residency (utility bill), insurance info (card, denial letter if applicable).[Provided data] 5. **Submit both forms** (both required—no action without them): - **Online**: Via My Patient Solutions (if registered) or direct links.[3] - **Print & Fax**: 833-999-4363. - **Text photo**: 650-877-1111.[3] - Multiple methods available.[Provided data] 6. **Wait for processing**: 5 business days after receiving both forms. You/provider contacted with outcome.[1][3] ## Timeline and Delivery - **Processing**: Within **5 business days** of complete submission.[1][3] - **Approval notification**: Call/email to you and provider.[1] - **Delivery**: Medicine shipped free to your home or doctor's office; accepted at participating pharmacies, offices, hospitals.[1][4] - **Retroactive**: Covers claims up to 180 days pre-enrollment if submitted within 365 days.[1][4] - **Auto-reenrollment**: Annually January 1st if eligible; removed after 3 years inactivity.[1][4] - **Reauthorization**: Required—reauthenticate annually or as needed.[Provided data] ## Alternatives if Denied - **Appeal**: Contact Foundation Specialist at (888) 941-3331 to discuss.[1] - **Other Genentech programs**: Genentech Oncology Co-pay Assistance for insured with commercial coverage.[5] - **Independent foundations**: PHESGO Access Solutions refers eligible patients.[8] - **State programs**, manufacturer discounts, or low-cost generics (none listed for PHESGO).[Provided data] - **Financial counselor**: Ask your oncologist or hospital for local aid. ## Important Disclaimer This guide is for informational purposes only and based on current program details as of available data. **Genentech reserves the right to change, verify, or end the program anytime**—criteria may update. Not a guarantee of approval. Consult your doctor for medical advice; do not change treatment without guidance. Report benefits to insurers as required. Program void where prohibited; US only. For latest info, visit GenentechPatientFoundation.com or call (888) 941-3331. (Word count: 1028)

Program information last verified: March 25, 2026