Perjeta

Indicated For

HER2-positive breast cancer

About This Medication

# Genentech Patient Assistance Program (via Access Solutions) Patient Guide: How to Get Perjeta (pertuzumab) at Low or No Cost Perjeta (pertuzumab) is a targeted therapy used in combination with other drugs like Herceptin and chemotherapy to treat HER2-positive metastatic breast cancer or as neoadjuvant treatment for certain early-stage cases. The **Genentech Patient Assistance Program**, accessed through **Genentech Access Solutions** and the **Genentech Patient Foundation**, helps eligible U.S. patients get **Perjeta** at low or no cost if they face financial hardship due to lack of insurance or high out-of-pocket costs.[1][2][5] ## About Perjeta (pertuzumab) **Perjeta** is a monoclonal antibody that binds to the HER2 receptor on cancer cells, blocking growth signals and enhancing the effectiveness of other HER2-targeted treatments. It's FDA-approved for: - Use with Herceptin (trastuzumab) and docetaxel for HER2-positive metastatic breast cancer in patients who haven't received prior anti-HER2 therapy or chemotherapy for metastatic disease. - Neoadjuvant treatment (before surgery) with Herceptin and chemotherapy for HER2-positive early breast cancer that is locally advanced, inflammatory, or node-positive.[5][6] Common side effects include diarrhea, nausea, fatigue, and hair loss, but serious risks like heart failure or infusion reactions require monitoring by your doctor. Always discuss benefits and risks with your oncologist. This program focuses on affordability, not medical advice.[1] ## Who Qualifies? The program targets U.S. patients (no citizenship check required) prescribed a Genentech medicine like Perjeta, treated by a U.S.-licensed physician. You may qualify if you fall into one of these **three main groups**:[5][7] 1. **Uninsured or underinsured** with **household income under $150,000** (some exceptions apply). 2. **Insured** but with an **out-of-pocket maximum >7.5% of yearly income**, based on household size and income. 3. **Financial need** where insurance doesn't cover Perjeta or cost-sharing is unaffordable. **Important exclusions**: - Patients whose insurance or employer **requires** applying to a Patient Assistance Program (PAP) as a coverage condition. - Those in Patient Assistance Diversion Programs (PADP), which may delay treatment.[5][7] No specific **Federal Poverty Level (FPL)** percentage is listed, but income is evaluated holistically. Use the online Confirm Financial Eligibility tool or call to check.[7] ## Income Eligibility Breakdown Exact thresholds aren't publicly detailed beyond $150,000 for some cases, but eligibility considers household income, size, and insurance. Here's a general guide based on program criteria:[5] | Household Size | Max Income (Uninsured/Underinsured) | Insured with OOP >7.5% Income | |----------------|-------------------------------------|-------------------------------| | Individual | Under $150,000* | Varies by plan OOP | | Couple | Under $150,000* | Varies by plan OOP | | Family of 3 | Under $150,000* | Varies by plan OOP | | Family of 4+ | Under $150,000* | Varies by plan OOP | *Some exceptions; full review required. Contact (888) 941-3331 for personalized assessment.[5][7] ## Insurance Requirements - **No insurance**: Eligible if income qualifies. - **Private insurance**: Eligible if OOP costs exceed 7.5% of income. - **Medicare/Medicaid/public programs**: May qualify if unaffordable cost-sharing; program doesn't require prior denial but verifies coverage.[5][6] - Insurance can't mandate PAP application or alter/hide coverage to force eligibility.[5][8] Genentech Access Solutions helps navigate coverage first.[4][6] ## Step-by-Step Application Process Applications require **two forms**: Patient Consent Form (you complete) and Prescriber Foundation Form (your doctor completes). Submit **together** for processing.[1][5] 1. **Prepare**: Gather income proof (tax returns, pay stubs—details confirmed via call), prescription, insurance info. 2. **Complete Patient Consent Form**: - Online: gene.com/patients/enrollment or GenentechPatientFoundation.com (English/Spanish).[1] - Print, sign, scan. 3. **Doctor completes Prescriber Foundation Form** (Page 2).[5] 4. **Submit both**: - **eSubmit** online (fastest). - **Text** photo to 650-877-1111. - **Fax** to 833-999-4363. - My Patient Solutions portal if doctor's office registered.[1][5] 5. **Phone support**: Call **1-888-249-4918** (Access Solutions) or **(888) 941-3331** (Foundation, M-F 6am-5pm PT).[1][6] ## Timeline and Delivery - **Processing**: Within **5 business days** of receiving both forms. You'll and your doctor be contacted with outcome/next steps.[1][5] - **Approval**: Free medicine shipped to doctor's office or pharmacy; details provided post-approval. - **Duration**: Varies; reauthorization often needed (see FAQ).[1] ## Alternatives if Denied - **Genentech Access Solutions** for copay cards, coverage appeals (if insured).[4][6] - **Biosimilar**: **Poherdy (pertuzumab-dpzb)** by Organon/Henlius—discuss with doctor as lower-cost option. - Other PAPs like PAN Foundation, NeedyMeds, or state programs. - Appeal denial by calling (888) 941-3331.[7] ## Disclaimer This guide is for informational purposes based on publicly available data as of 2026. Eligibility, processes, and terms can change—**always verify with Genentech at (888) 941-3331 or gene.com/patients**. Not medical/financial advice. Consult your doctor for treatment decisions. Genentech not liable for application errors.[1][2] (Word count: 912)

Program information last verified: March 30, 2026