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Oncology

PEMfEXY

Generic: pemetrexed

Manufacturer: Eagle Pharmaceuticals  ·  Program: EAGLE CAN Patient Assistance Program

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Qualifying uninsured or underinsured patients

Residency

US resident

Eligibility requirements not detailed online; contact program for details

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient or physician office

Application Method

Fax

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • completed enrollment form
  • proof of income
  • proof of residency
  • prescriber signature

Indicated for

non-squamous non-small cell lung cancer (NSCLC), malignant pleural mesothelioma

About This Medication

EAGLE CAN Patient Assistance Program Patient Guide: How to Get PEMfEXY (pemetrexed) at Low or No Cost

PEMFEXY (pemetrexed) is a chemotherapy medication used to treat certain types of lung cancer, such as non-small cell lung cancer (NSCLC) and mesothelioma, for FDA-approved indications. The EAGLE CAN Patient Assistance Program from Eagle Pharmaceuticals provides qualifying uninsured or underinsured patients with PEMfEXY at no cost, helping reduce financial barriers to essential treatment.[1][2]

Who Qualifies for the Program?

To be eligible, you must meet all these criteria:

  • Prescribed PEMfEXY for an FDA-approved use by your healthcare provider (HCP).
  • Annual Adjusted Gross Household Income at or below 500% of the Federal Poverty Guidelines (FPL) based on your household size and location. Check current guidelines at https://aspe.hhs.gov/poverty-guidelines.[1]
  • Qualifying as uninsured or underinsured (program assists those whose insurance does not fully cover the medication).[1][2]

The program is designed for patients facing high out-of-pocket costs, offering free medication shipped to you or your doctor's office.[1]

About PEMFEXY (pemetrexed)

PEMFEXY is an injectable chemotherapy drug that works by interfering with cancer cell growth and division. It's commonly used:

  • In combination with other drugs for advanced non-squamous NSCLC.
  • For maintenance treatment after initial therapy.
  • To treat malignant pleural mesothelioma with cisplatin.[1]

Your doctor will administer it intravenously, often with vitamin supplementation (folic acid, vitamin B12) and steroids to reduce side effects like nausea, fatigue, low blood counts, or rash. Always follow your prescriber's instructions. This program focuses on financial access, not medical advice—discuss treatment with your oncologist.[1][2]

Income Eligibility Breakdown

Eligibility hinges on household income ≤ 500% FPL. Use the table below for 2025 U.S. guidelines (continental U.S.; Alaska/Hawaii higher—verify current at ASPE site). Adjusted Gross Income from tax returns qualifies.[1]

Household Size100% FPL500% FPL (Max Eligible Income)
1$15,060$75,300
2$20,440$102,200
3$25,820$129,100
4$31,200$156,000
+1 person+$5,380+$26,900

Notes: Includes all household income. Provide proof like tax returns, pay stubs, or W-2s. Contact program if self-employed or complex finances. Thresholds update annually.[1]

Insurance Requirements

The program targets uninsured or underinsured patients. 'Underinsured' means insurance denies coverage, partially pays, or leaves high costs after appeals.[1][3]

  • No Medicare/Medicaid? Likely qualify if income-eligible.
  • Private insurance? Submit denial/EOB after appeal; partial pay isn't denial.[3]
  • Program offers benefits investigation first; if ineligible for copay help, refers to PAP for free drug.[2][8] Call 1-833-324-5322 to check coverage before applying.[1]

Step-by-Step Application Process

  1. Get Prescribed: Ensure your doctor prescribes PEMfEXY for FDA-approved use. Download forms from eaglecanus.com.[1][3]
  2. Complete Enrollment Form: Fill Patient Section (name, DOB, income, insurance details). Doctor completes Prescriber Section (signature required—no stamps).[1][4]
  3. Gather Documents:
    • Proof of income (tax return, pay stubs).
    • Proof of residency (utility bill, etc.).
    • HCP signature.[1]
  4. Sign Agreements: Patient signs consent; agree to terms.[1]
  5. Fax Everything: Send to 1-833-324-5346 (1-833-EAGLE-GO). Incomplete forms delay processing.[1][4]
  6. Follow Up: Call 1-833-324-5322 (Mon-Fri, 9am-5pm EST) for status. HCP can assist.[1]

Your HCP may help obtain docs or submit.[1]

Timeline and Delivery

Processing time varies; fax speeds it up. Expect contact for more info if needed.[1] Once approved, PEMfEXY ships free to patient or physician office.[1][2] Track via program phone.[1]

Alternatives if Denied

  • Appeal Insurance: Submit one-level appeal per payer rules; resubmit EOB.[3]
  • Copay Programs: EAGLE CAN offers copay help via TailorMed for insured; digital enrollment.[9]
  • Other Foundations: PAN, Healthwell, CancerCare (via Giant Eagle or similar).[7]
  • RxAssist: Search more PAPs.[5][8]
  • Reapply if circumstances change; call for guidance.[1]

Important Disclaimer

This guide summarizes public info as of 2025; eligibility/details change. Contact EAGLE CAN at (833) 324-5322 for latest. Not medical/financial advice—consult doctor/tax pro. Program may request more docs. Eagle reserves rights to modify/deny.[1][2] Word count: 942.

Program information last verified: March 30, 2026

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