PEMAZYRE

Indicated For

cholangiocarcinoma

About This Medication

# IncyteCARES for PEMAZYRE Patient Assistance Program Patient Guide: How to Get PEMAZYRE at Low or No Cost PEMAZYRE® (pemigatinib) is a prescription medication used to treat certain types of advanced bile duct cancer, known as cholangiocarcinoma, with specific genetic mutations (FGFR2 fusion or rearrangement, or FGFR3 mutation). The **IncyteCARES for PEMAZYRE Patient Assistance Program** from Incyte helps eligible uninsured or underinsured patients in the US or Puerto Rico get PEMAZYRE free of charge if they meet income and other criteria[1][5]. ## About PEMAZYRE PEMAZYRE is an oral targeted therapy approved by the FDA for adults with previously treated, unresectable, locally advanced or metastatic cholangiocarcinoma with FGFR2 fusion or other FGFR alterations. It works by blocking specific proteins (FGFR kinases) that cancer cells use to grow. Common side effects include eye problems (like dry eyes or retinal issues), fatigue, nausea, diarrhea, and changes in taste or phosphate levels. Always take it exactly as prescribed, typically once daily on an empty stomach. Your doctor will monitor you closely, especially your eyes and bloodwork. For full details, review the prescribing information with your healthcare provider[1][4]. ## Who Qualifies for the Program? This program is for **uninsured or underinsured patients** who can't afford PEMAZYRE. You must: - Live in the United States or Puerto Rico. - Have a valid prescription for an FDA-approved use of PEMAZYRE. - Be enrolled in IncyteCARES for PEMAZYRE. - Meet **household income criteria** (specific thresholds not publicly listed; program evaluates based on household size and income—contact them for your situation)[1][5]. **Three main insurance situations qualify**: - **Uninsured**: No prescription drug coverage at all. - **Medicare Part D**: Enrolled and meet income limits. - **Any insurance (commercial, Medicaid, etc.)**: But coverage for PEMAZYRE is exhausted or denied, plus meet income limits. **Note**: Government programs like Medicare Part D are allowed only for the PAP (not the copay/savings program). Purely commercially insured patients may use a separate savings program for low copays, but this guide focuses on the free drug PAP[1][2]. ## Income Eligibility Breakdown Income limits are based on household size and **federal poverty level (FPL)**, but exact percentages aren't specified publicly. The program requires proof of household income and reviews case-by-case. Here's a general overview—**call (855) 452-5234 for your personalized eligibility**. | Household Size | Estimated Max Income (Example: 400% FPL, 2026)* | Notes | |---------------|------------------------------------------------|-------| | 1 person | ~$60,000 | Contact program for exacts[1] | | 2 people | ~$81,000 | Household income only[1] | | 3 people | ~$102,000 | Includes all household[5] | | 4 people | ~$123,000 | Proof required[1] | | 5+ people | Add ~$21,000 per person | Varies; call to confirm | *Illustrative based on typical PAPs; actuals may differ. Program confirms during enrollment[1][2]. ## Insurance Requirements - **Uninsured**: No drug coverage needed, just income proof. - **Underinsured**: Medicare Part D OK if low-income; other insurance OK if PEMAZYRE denied/exhausted (provide denial letter). - **Not eligible**: Standalone government coverage without denial/income meet (e.g., Medicaid alone may not qualify unless denied)[1]. IncyteCARES verifies benefits and helps with appeals[3]. ## Step-by-Step Application Process 1. **Get Prescribed**: Ask your doctor for PEMAZYRE and discuss IncyteCARES. 2. **Enroll**: Your doctor or you can: - Call **(855) 452-5234** (Mon-Fri, 8 AM–8 PM ET). - Complete online at IncyteCARESsavings.PEMAZYRE.com. - Download/fax form from hcp.incytecares.com[1][6]. 3. **Provide Info**: Doctor signs; submit proof of income (tax returns, paystubs), prescription, insurance status/denial. 4. **Conditional Approval**: Within **3 business days**, get notice for 90 days free PEMAZYRE while verifying income[1][5]. 5. **Full Approval**: Submit income proof for ongoing supply. Takes ~15 minutes to start[1]. ## Timeline and Delivery - **Processing**: 2-3 business days for conditional approval[1][2][5]. - **Delivery**: Shipped free via **Biologics by McKesson** specialty pharmacy. They call to coordinate, provide support (refill reminders, education)[1]. - **Supply**: 90 days initially; reauthorization needed. - **Short-term help**: Free bridge supply if insurance delays >5 days (commercial only)[1]. ## Alternatives if Denied - **Copay Savings Card**: For commercial insurance—$0 copay up to limits (ask doctor)[10]. - **Appeal**: Resubmit with more docs or appeal denial[3]. - **Other PAPs**: Check RxAssist.org or NeedyMeds for copay help[9]. - **State programs**: Local Medicaid or charity care. - **Clinical trials**: Ask oncologist for FGFR+ trials. No biosimilars available[provided data]. ## Reauthorization and Refills **Reauthorization required**. Biologics handles refills with text reminders. Submit updated docs annually or as needed[1]. ## Disclaimer This guide is for informational purposes based on program details as of 2026. Eligibility, terms, and availability can change. No guarantee of approval. Consult your doctor and call IncyteCARES at (855) 452-5234 for latest info. Not affiliated with Incyte. Always verify with official sources[1][5]. (Word count: 942)

Program information last verified: March 25, 2026