Padcev

PADCEV Patient Connect Program Patient Guide: How to Get Padcev (enfortumab vedotin-ejfv) at Low or No Cost

Padcev (enfortumab vedotin-ejfv) is a prescription medication used to treat certain types of advanced bladder cancer, known as locally advanced or metastatic urothelial carcinoma (la/mUC). The PADCEV Patient Connect Program, offered by Astellas Pharma and Pfizer through PADCEV Support Solutions, provides financial help to make Padcev more affordable, including a Copay Assistance Program for commercially insured patients and a Patient Assistance Program (PAP) for uninsured patients who qualify.[1][2]

About Padcev and Who It's For

Padcev is an antibody-drug conjugate that targets Nectin-4 on cancer cells, delivering a chemotherapy agent directly to tumors. It's approved for adults with la/mUC who have previously received a PD-1/PD-L1 inhibitor and platinum chemotherapy, or who are cisplatin-ineligible and have had prior therapy. It can also be used with Keytruda (pembrolizumab) as an alternative to platinum chemotherapy in some cases.[5]

This guide explains the PADCEV Patient Connect Program, which connects patients to two main assistance options:

• Copay Assistance Program: Reduces out-of-pocket costs for eligible commercially insured patients.
• Patient Assistance Program (PAP): Provides Padcev at no cost to qualifying uninsured patients.[1][2]

The program also offers Patient Connect support, linking you to third-party resources for emotional, logistical, and informational help, like counseling, transportation, or nutrition advice.[1][3]

Who Qualifies?

Eligibility varies by program:

• Copay Assistance Program:

  • Must have private commercial health insurance (not government programs like Medicare, Medicaid, or VA).
  • No income requirements.
  • Covers up to $25,000 per calendar year, with patients paying as little as $5 per dose.
  • Enrollment lasts 12 months.[2]

• Patient Assistance Program (PAP):

  • For uninsured patients who meet program requirements (specific income thresholds not detailed publicly; call for details).[1]
  • Padcev is provided at no cost.[1]

Contact PADCEV Support Solutions at 1-888-402-0627 (Mon–Fri, 8:30 AM–8:00 PM ET) to check eligibility.[1][2]

Income Eligibility Breakdown

The Copay Program has no income limits, making it accessible to a wide range of commercially insured patients. For PAP, income guidelines apply but are not publicly specified—eligibility is assessed case-by-case for uninsured patients.[1][2]

Here's a summary table:

Note: Federal/state healthcare program patients (e.g., Medicare) are ineligible for Copay Assistance.[2]

Insurance Requirements

• Commercial Insurance: Eligible for Copay Program if not on government insurance. The program helps cover copays, coinsurance, or deductibles.[2]
• Uninsured: Qualify for PAP if meeting other criteria.[1]
• Government Insurance (Medicare, Medicaid, etc.): Not eligible for Copay Program. Explore other options like Medicare Extra Help or state programs. Patient Connect may link to additional resources.[1][2]

PADCEV Support Solutions can verify coverage and suggest alternatives.[1]

Step-by-Step Application Process

Your healthcare provider (HCP) plays a key role. Here's how to apply:[1][4][7]

1. Discuss with Your HCP: Ask about Padcev and PADCEV Support Solutions. They can start the process.

2. Choose Enrollment Method (3 options):[4]

   • Fax: HCP completes the Patient Enrollment Form (downloadable), signs it with you, and faxes to 1-877-747-6843.[4][7]
   • Online: HCP logs into the Prescriber Portal to submit the form electronically.[4]
   • Phone: Call 1-888-402-0627 (Mon–Fri, 8:30 AM–8:00 PM ET) to enroll with help from a specialist.[1][4]

3. Submit Required Info: Includes patient details, HCP signature, prescription, and insurance info (if applicable). For PAP, additional eligibility proof may be needed.[1][7]

4. Approval Notification: If approved, you and your HCP are notified. For PAP, drug ships to HCP's office.[1]

5. Access Support: Enrolled patients get Patient Connect resources tailored to needs.[1]

Call for help anytime—specialists guide you through.[1]

Timeline and Delivery

• Processing: Not specified; call for status updates. Approvals lead to quick notification.[1]
• Delivery: For PAP, Padcev ships directly to your HCP (not home). Pick up from their office.[1]
• Copay Cards: Issued digitally or by mail for immediate use at pharmacy.[2]

Expect 1-2 weeks typically, but phone support expedites.[1][4]

Alternatives if Denied or Ineligible

• Switch Programs: If denied Copay, check PAP (if uninsured).[1]
• Patient Connect: Get referrals to independent organizations for financial aid, transportation, or emotional support.[1][3]
• Other Resources:
  • PAN Foundation or CancerCare grants.
  • State pharmaceutical assistance programs.
  • Medicare Savings Programs (if applicable).[2]
• Generic/Biosimilar: None available for Padcev.[5]
• Contact Support: Call 1-888-402-0627 for personalized options.[1]

Reauthorization and Refills

Copay enrollment lasts 12 months; reapply annually. PAP may require periodic HCP confirmation. Your HCP handles refills via the portal or phone.[2][4]

Important Disclaimer

This guide is for informational purposes based on publicly available data as of 2024. Program details can change; always verify with PADCEV Support Solutions at 1-888-402-0627 or PADCEVSupportSolutions.com. Not all patients qualify. PADCEV has serious side effects (see full Prescribing Information, including Boxed Warning). Consult your HCP. Astellas/Pfizer reserve rights to modify/terminate programs. Support via Patient Connect is through independent third parties, not guaranteed.[1][2][7]