Orladeyo

Indicated For

Hereditary Angioedema (HAE)

About This Medication

# Empower Patient Services Patient Guide: How to Get ORLADEYO at Low or No Cost ## About ORLADEYO (Berotralstat) ORLADEYO is an oral medication developed by BioCryst Pharmaceuticals for patients with hereditary angioedema (HAE). HAE is a rare genetic condition that causes unpredictable swelling episodes in various parts of the body. ORLADEYO works by helping to prevent these attacks, allowing patients to maintain better control of their condition and improve their quality of life. ## What is Empower Patient Services? Empower Patient Services is BioCryst Pharmaceuticals' patient assistance program designed to help patients access ORLADEYO regardless of their insurance status. The program provides financial support, medication coordination, and personalized assistance to ensure eligible patients can afford their treatment. ## Who Qualifies? Empower Patient Services offers reimbursement and financial assistance for all patients, regardless of insurance status. This means: - **Uninsured patients** may qualify for free or reduced-cost medication - **Underinsured patients** with high copays or deductibles may receive copay assistance - **Commercially insured patients** can access $0 copay assistance programs - **Medicare and Medicaid patients** should contact the program directly to discuss eligibility The program does not have publicly disclosed income thresholds, meaning eligibility is evaluated on a case-by-case basis. Even if you believe your income is too high, it's worth applying—the program may still be able to help. ## Insurance Requirements Empower Patient Services primarily serves commercially insured patients and offers $0 copay assistance to reduce or eliminate your out-of-pocket costs. If you have Medicare, Medicaid, or are uninsured, contact the program directly to learn about your specific options. ## How to Apply While specific application methods are not detailed in available program materials, Empower Patient Services provides 1-on-1 support to help you access and start ORLADEYO. Here's what you should do: 1. **Contact the program** through BioCryst's patient services team to express interest in assistance 2. **Provide basic information** about your insurance status, income, and current HAE treatment 3. **Work with a patient advocate** who will guide you through the application process 4. **Submit required documentation** as requested by the program (typically including proof of income and insurance information) 5. **Receive approval** and begin coordinating your medication delivery ## Program Features Once enrolled in Empower Patient Services, you'll have access to: - **Monthly refill coordination** on your schedule - **Medication reminders** to help you stay on track - **Progress tracking** tools to monitor your HAE management - **Easy communication** with your healthcare provider to share updates - **1-on-1 patient support** to answer questions and address concerns ## Timeline and Delivery Specific processing times and delivery methods are not detailed in available program information. After applying, you should expect: - **Initial response** within a reasonable timeframe after submitting your application - **Approval notification** once your eligibility is confirmed - **Medication delivery** coordinated through the program For exact timelines and delivery details, contact Empower Patient Services directly. ## What If Your Application Is Denied? If you're denied assistance through Empower Patient Services, consider these alternatives: - **Appeal the decision** by providing additional documentation or updated financial information - **Explore BioCryst's Expanded Access Program** if you have a serious or life-threatening condition and no other treatment options are available - **Discuss payment plans** with your healthcare provider or pharmacy - **Contact patient advocacy organizations** focused on HAE for additional resources ## Reauthorization Program reauthorization requirements are not specified in available materials. Once enrolled, maintain regular contact with your patient advocate to ensure continuous coverage and discuss any changes in your circumstances. ## Important Disclaimer This guide provides general information about Empower Patient Services based on available program details. Program eligibility, benefits, and requirements may change. For the most current and complete information, contact BioCryst Pharmaceuticals' patient services team directly. This guide is not a guarantee of assistance or coverage. Always verify your eligibility and coverage details with the program before making treatment decisions. ## Next Steps If you're interested in ORLADEYO and need financial assistance, reach out to Empower Patient Services today. The program's patient advocates are available to answer your questions and help you navigate the application process. Don't let cost concerns prevent you from exploring treatment options for your HAE.

Program information last verified: March 30, 2026