ONTRUZANT

Indicated For

HER2+ breast cancer, HER2+ gastric cancer

About This Medication

# Organon Patient Assistance Program Patient Guide: How to Get ONTRUZANT (trastuzumab-dttb) at Low or No Cost ONTRUZANT (trastuzumab-dttb) is a biosimilar to Herceptin used to treat certain types of breast cancer and gastric cancer that overexpress the HER2 protein. The **Organon Patient Assistance Program** provides this medication **free of charge** to eligible uninsured or underinsured patients who meet income and other criteria. ## About ONTRUZANT (trastuzumab-dttb) **ONTRUZANT** is an intravenous biosimilar monoclonal antibody that targets the HER2 receptor, helping to slow or stop the growth of HER2-positive cancer cells. It is FDA-approved for use in combination with chemotherapy for adjuvant treatment of HER2-overexpressing node-positive or node-negative breast cancer, metastatic breast cancer, and metastatic gastric cancer. Administered by a healthcare professional, it is typically given every 1-3 weeks depending on the treatment regimen. Common side effects include infusion reactions, fatigue, nausea, diarrhea, and increased risk of heart problems—always discuss risks with your doctor. This program ensures financial barriers do not prevent access to this critical therapy for qualifying patients. ## Who Qualifies for the Program? The program is designed for **U.S. residents** (higher limits for Alaska and Hawaii) who are **primarily uninsured** or underinsured and cannot afford their medication. Key eligibility factors include: - **Household income** at or below specified thresholds (detailed below). - **No or limited insurance** coverage for ONTRUZANT. - A valid prescription from a U.S.-licensed healthcare provider. - Proof of residency in the U.S. Patients with Medicare Part D or government insurance may have limited enrollment, often until the end of the calendar year. ## Income Eligibility Breakdown Eligibility is based on **annual gross household income**. Limits are: | Household Size | Annual Income Limit | |----------------|---------------------| | Individual | $79,800 | | Couple | $108,200 | | Family of 3+ | Call for details (higher for larger families, Alaska/Hawaii) | **Notes**: Income includes all household members' gross earnings before taxes. Higher thresholds apply in Alaska and Hawaii—contact the program for exact figures. The program reserves the right to verify income via audits. ## Insurance Requirements - **Primarily for uninsured patients**. - **Underinsured patients** may qualify if insurance does not cover ONTRUZANT or if out-of-pocket costs are unaffordable. - **Medicare Part D or government insurance**: Enrollment may end at calendar year-end; co-pay programs may be separate. - The **Organon Access Program** can help investigate benefits, prior authorizations, or appeals before applying for patient assistance. ## Step-by-Step Application Process 1. **Confirm Eligibility**: Use the income quiz on organonhelps.com or call **(888) 727-0015** (Mon-Fri, 8 AM-8 PM ET) to check if you qualify. 2. **Get Your Prescription**: Ask your doctor for a prescription for ONTRUZANT. 3. **Download or Request Enrollment Form**: Visit the ONTRUZANT-specific Organon Access Program page (organonaccessprogram-ontruzant.com) or call **(888) 727-0015** to get the form. Complete it with your doctor. 4. **Gather Required Documents**: - Completed **Enrollment Form** (signed by you and your prescriber). - **Prescription** for ONTRUZANT. - **Proof of income** (e.g., tax returns, pay stubs, W-2s). - **Proof of residency** (e.g., utility bill, lease). 5. **Submit Application**: - **Phone**: Call **(888) 727-0015** to start. - **Fax/Mail**: Fax to the number on the form (e.g., 800-538-5812 or 833-520-1491) or mail to Organon Patient Assistance Program, P.O. Box 991624, Louisville, KY 40269. - Electronic submission may be available via CoverMyMeds. 6. **Follow Up**: A representative will contact you and your doctor's office. You'll receive a letter or text on approval/denial. ## Timeline and Delivery - **Processing**: Expect contact within days to weeks; exact time varies. - **Approval Duration**: Up to **12 months** from enrollment date (shorter for government insurance). - **Delivery**: Medication is **shipped free directly to you** or your doctor's office for administration. - **Reauthorization**: Required annually or before enrollment ends; program notifies you with your last refill. ## Alternatives if Denied - **Appeal**: Contact the program for reasons and next steps. - **Organon Co-pay Assistance**: For commercially insured patients to reduce out-of-pocket costs. - **Biosimilar Alternative**: Herceptin (trastuzumab)—check other manufacturer programs. - **Other Resources**: State programs, non-profits like PAN Foundation, or NeedyMeds.org. - **Doctor's Help**: Ask about samples, payment plans, or generic/biosimilar switches. ## Important Disclaimer This guide is for informational purposes only and based on publicly available program details as of 2025. Eligibility, terms, and income limits can change—**always verify with the program at (888) 727-0015**. Not affiliated with Organon. Consult your healthcare provider before starting treatment. Organon reserves the right to modify or end the program. Free medication is not contingent on future purchases.

Program information last verified: March 30, 2026