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Neurology

Oleptro

Generic: trazodone hydrochloride

Manufacturer: Angelini Pharma Inc.  ·  Program:

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Eligibility Criteria

Insurance Requirement

See program details

Residency

US residency required

Program Information

Processing Time

2–4 weeks

Delivery Method

Varies by program

Application Method

Online

Indicated For

Major Depressive Disorder (MDD)

About This Medication

# Angelini Pharma Inc. Patient Assistance Program Guide: How to Get Oleptro (Trazodone Hydrochloride) at Low or No Cost Oleptro (trazodone hydrochloride extended-release tablets) is a prescription medication used to treat **major depressive disorder (MDD)** in adults, offering an extended-release formulation that can be taken once daily, typically in the evening.[1][5][6] This patient-friendly guide explains how to access potential assistance for Oleptro through Angelini Pharma Inc., though specific program details are limited as no dedicated patient assistance program (PAP) is prominently listed in current resources—contact the manufacturer directly for eligibility and application support.[1][3][6] ## About Oleptro Oleptro is an antidepressant classified as a serotonin modulator that helps restore balance in brain chemicals to alleviate symptoms of depression, such as persistent sadness, loss of interest, and sleep disturbances.[5][7] Unlike immediate-release trazodone, Oleptro uses proprietary Contramid technology for controlled release over 24 hours, available in **150 mg** (yellowish-beige, scored) and **300 mg** (beige-orange, scored) bisectable tablets that maintain extended-release properties even when split.[1][5][6] **Key dosing info**: Start at 150 mg once daily, increasing by 75 mg every 3 days if needed, up to a maximum of 375 mg/day. Take at the same time each evening.[1] It's not approved for pediatric use, and patients should be monitored for worsening depression or suicidal thoughts, especially early in treatment.[1][5] **Common side effects** include drowsiness, dizziness, constipation, and blurred vision. Report serious issues to Angelini Pharma at 1-877-345-6177 or FDA at 1-800-FDA-1088.[1] Always consult your doctor before starting or changing doses, as Oleptro interacts with certain drugs like MAOIs and requires caution in patients with heart conditions or hypotension.[1][9] Treatment often continues for months after symptom improvement at the lowest effective dose, with periodic reassessment.[1] ## Who Qualifies for Assistance? Angelini Pharma Inc., the manufacturer of Oleptro, may offer support for uninsured or underinsured patients facing financial hardship, similar to other pharmaceutical PAPs.[1][4] However, no specific **income thresholds**, program name, or detailed eligibility criteria are publicly detailed in available sources.[3] Typical PAPs target those at or below **300-400% of the Federal Poverty Level (FPL)**, but confirmation is needed from Angelini. **General eligibility factors** (based on standard PAP practices): - U.S. resident with a valid prescription for Oleptro. - Household income meeting guidelines (often adjusted for family size). - Lack of sufficient insurance coverage or high copays. - Not enrolled in federal programs like Medicaid (though some allow Medicare Part D 'Extra Help').[4] **Note**: Oleptro's status appears 'dormant' in some databases as of 2017, which may impact availability—verify with your pharmacy or manufacturer.[3] Contact Angelini at **1-877-345-6177** (from product labeling) for current program status.[1][6] ## Income Eligibility Breakdown Specific thresholds for Angelini are unavailable. Below is a generalized table based on common PAP structures (e.g., 400% FPL). **Always confirm directly with Angelini**, as guidelines change. | Household Size | Max Annual Income (400% FPL, 2026 est.) | Notes | |---------------|-----------------------------------------|-------| | 1 (Individual) | ~$60,000 | Entry-level eligibility; proof required. | | 2 (Couple) | ~$81,000 | Common for spouses/partners. | | 3 | ~$102,000 | Includes dependents. | | 4 | ~$123,000 | Adds ~$21,000 per additional member. | *Estimates based on 2026 FPL projections; actuals vary. Some programs go up to 500% FPL or include deductions for medical expenses.*[4] ## Insurance Requirements Most PAPs, including those like Angelini's potential program, require patients to be uninsured or underinsured—meaning commercial insurance with high copays/deductibles, but often exclude those on government programs like Medicaid.[4] Medicare patients may qualify if enrolled in Extra Help but face restrictions. Provide proof of insurance denial or copay assistance need. Angelini details unavailable—call to confirm.[1] ## Step-by-Step Application Process 1. **Get a prescription**: Ask your doctor for Oleptro and discuss if PAP assistance is needed. 2. **Contact Angelini**: Call **1-877-345-6177** or visit www.oleptro.com (if active) to inquire about PAP, request application.[1][6] 3. **Gather documents**: Typically include proof of income (tax returns, pay stubs), prescription, ID, insurance info.[4] 4. **Complete application**: Doctor/patient submits via mail, fax, or online (methods TBD by Angelini). 5. **Submit and follow up**: Track status via phone. ## Timeline and Delivery Processing typically takes **2-4 weeks** for standard PAPs, with initial approval granting 1-12 months' supply shipped to your doctor or pharmacy.[4] Refills may require reapplication. Expect free or low-cost delivery via mail. ## Alternatives if Denied or Ineligible - **Generic trazodone HCl**: Cheaper immediate-release option; ask your doctor about switching.[1] - **Other PAPs**: Check PAN Foundation or RxAssist for depression meds.[4] - **State programs**: 340B clinics, Medicaid, or coupons via GoodRx. - **Manufacturer samples**: Request from your doctor. - No biosimilars listed for Oleptro.[ ] ## Disclaimer This guide is for informational purposes only and not medical or financial advice. Program details may have changed; **contact Angelini Pharma Inc. at 1-877-345-6177 directly** for accurate, current info.[1][6] Consult your healthcare provider for treatment decisions. Availability of Oleptro may be limited due to dormant status in some markets.[3] Word count: 942.

Program information last verified: March 30, 2026

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