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Neurology

OCREVUS

Generic: ocrelizumab

Manufacturer: Genentech  ·  Program: OCREVUS Co-pay Program

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Eligibility Criteria

Insurance Requirement

Eligible commercially insured patients; not valid for patients whose prescriptions are reimbursed under federal or state government programs

Residency

US resident

Individual Income Limit

$150,000/year

Income cap ~$150,000/year regardless of household size; varies by drug

Program Information

Processing Time

2–3 weeks

Delivery Method

shipped to patient or physician office

Application Method

Multiple

Reauthorization

Required — annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • OCREVUS Start Form
  • Patient Consent Form
  • Proof of FDA-approved indication

Indicated For

Relapsing Multiple Sclerosis (RMS), Primary Progressive Multiple Sclerosis (PPMS)

About This Medication

# OCREVUS Co-pay Program Patient Guide: How to Get OCREVUS at Low or No Cost OCREVUS (ocrelizumab) is a prescription medication used to treat certain forms of **multiple sclerosis (MS)**, including relapsing forms of MS and primary progressive MS. The **OCREVUS Co-pay Program** from Genentech helps eligible commercially insured patients reduce out-of-pocket costs for OCREVUS or OCREVUS ZUNOVO (ocrelizumab & hyaluronidase-ocsq), potentially as low as $0 for drug and/or administration costs, up to $20,000 annually.[1][7] ## About OCREVUS OCREVUS is given as an infusion by a healthcare professional, typically every 6 months after initial doses. It's FDA-approved for adults with relapsing MS (including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease) or primary progressive MS. OCREVUS ZUNOVO is a newer subcutaneous option that may shorten administration time. This guide focuses on the co-pay program, which covers costs related to the drug and infusion/administration if you're insured privately.[1][4][5] ## Who Qualifies? **Eligibility is strict:** You must have **commercial (private) insurance**, not government programs like Medicare, Medicaid, or VA benefits. Your prescription must be for an **FDA-approved use**, and you must be 18+ or have a caregiver. The program assists with co-pays, co-insurance, or deductibles—not full medication costs for uninsured patients. Benefit limits apply, up to $20,000 per year, and it's not available where prohibited by law or your insurer.[1][5][7][8] ## Income Eligibility This co-pay program **does not have fixed income thresholds** like free drug programs. Instead, **income requirements vary by insurance status**—uninsured or underinsured patients may qualify for other Genentech options via referral, but this program targets commercially insured patients facing high out-of-pocket costs. No specific FPL (Federal Poverty Level) limits are listed; eligibility focuses on insurance type and prescription validity.[6] Here's a simple breakdown: | Category | Details | Notes | |----------|---------|-------| | **Commercially Insured** | Primary group; up to $20,000/year help | Must cover OCREVUS; program pays co-pay/co-insurance[7] | | **Government Insured (e.g., Medicare, Medicaid)** | **Not eligible** | Use Patient Navigator for foundation referrals[1][5] | | **Uninsured** | Not for this program | Try Genentech Patient Foundation (income-based)[6] | | **Income Thresholds** | Vary; no fixed FPL % | Depends on program type/insurance[6] | Always check OCREVUSCopay.com for your situation. ## Insurance Requirements - **Must have commercial/private insurance** covering OCREVUS. - **Invalid for federal/state programs**: Medicare (including Advantage/Medigap), Medicaid, TRICARE, VA, etc. - Your insurer can't prohibit co-pay assistance. - Program covers **drug costs and/or administration** (e.g., infusion fees), but total out-of-pocket depends on your plan. Some states (e.g., MA, RI) restrict administration help.[5][10] ## Step-by-Step Application Process 1. **Confirm Eligibility**: Verify commercial insurance and FDA-approved diagnosis with your doctor. 2. **Gather Documents**: - **OCREVUS Start Form** (completed by prescriber). - **Patient Consent Form**. - **Proof of FDA-approved indication** (e.g., medical records/chart notes). - Insurance details, pharmacy info.[8] 3. **Apply**: Multiple methods—call **(844) 627-3887** or visit [apply online](https://www.ocrevus.com/patient/financial-support/apply.html). HCPs can enroll via OCREVUSCopay.com/HCP.[1][3] 4. **Doctor Submits**: Prescriber often handles enrollment, linking providers to your account. 5. **Approval**: If approved, get a co-pay card for pharmacy/infusion center use. 6. **Use It**: Present card at specialty pharmacy or infusion site—covers eligible costs instantly.[4] ## Timeline and Delivery - **Processing Time**: Not specified; call for status. Many approvals are quick for co-pay programs. - **Delivery**: Via **specialty pharmacy** network. Medication ships to your provider or designated site for infusion. Track via program portal.[3] - **Re-enrollment**: Automatic annually if eligible; removed after 3 years inactivity.[5] - **Refills**: **Reauthorization required** periodically—doctor resubmits proof of ongoing need.[program details] ## Alternatives if Denied or Ineligible - **Independent Foundations**: OCREVUS Patient Navigator refers you (Genentech doesn't control approval).[6] - **Genentech Patient Foundation**: Free medicine for low-income uninsured/insured without coverage (separate income rules).[6] - **Biosimilars**: **OCREVUS ZUNOVO** (ocrelizumab & hyaluronidase-ocsq)—same program applies![4][7] - Call (844) 627-3887 for other options. ## Important Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. **Program terms can change**—visit OCREVUSCopay.com or call for latest details. **Not legal/medical advice**. Eligibility, benefits, and coverage vary. Genentech reserves rights to modify/discontinue. Consult your doctor/insurer. Patients may still owe co-pays based on plan.[1][5] *(Word count: 912)*

Program information last verified: March 30, 2026

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