Nyvepria

Pfizer Patient Assistance Program Patient Guide: How to Get Nyvepria at Low or No Cost

About This Program

The Pfizer Patient Assistance Program (PAP) is designed to help uninsured and underinsured patients access Pfizer medications, including Nyvepria (pegfilgrastim-apgf), at no cost or reduced cost. Nyvepria is a biosimilar to Neulasta used to help prevent infections in cancer patients receiving chemotherapy. If you're struggling to afford this medication, this program may be able to help.

What is Nyvepria?

Nyvepria is a pegfilgrastim biosimilar—a medication that works the same way as the original Neulasta to boost white blood cell production during cancer treatment. It helps reduce the risk of serious infections that can occur when chemotherapy lowers your immune system. Your doctor may have prescribed Nyvepria as a more affordable alternative to brand-name Neulasta.

Who Qualifies for This Program?

To be eligible for the Pfizer Patient Assistance Program, you must meet ALL of the following requirements:

• Age: Be 18 years or older
• Residency: Reside in the U.S. or a U.S. territory
• Healthcare Provider: Be treated by a licensed healthcare provider in the U.S. or a U.S. territory
• Insurance Status: Be uninsured OR insured through a government program (Medicare, Medicaid, VA, etc.)
• Income: Meet the income limits (typically up to 500% of the federal poverty level for most Pfizer products; oncology products may go up to 600%)
• Valid Prescription: Have a current prescription from your doctor for Nyvepria
• FDA-Approved Diagnosis: Have a diagnosis approved by the FDA for which Nyvepria is indicated

Important: Patients with commercial insurance (insurance through an employer or Federal Employer Plan) are not eligible for this program, even if they cannot afford their medication.

Income Eligibility

Income limits are based on the federal poverty level (FPL). For Pfizer oncology products like Nyvepria, the income threshold is typically 500% of the federal poverty level. This means your household income cannot exceed a certain amount based on your family size.

Note: These figures are estimates based on 2026 federal poverty guidelines. Exact limits may vary. Contact Pfizer at (800) 505-4426 to confirm current income thresholds.

Insurance Requirements

You are eligible if you:

• Have no insurance coverage, OR
• Are insured through a government program (Medicare, Medicaid, Veterans Affairs, TRICARE, etc.) and cannot afford your out-of-pocket costs

You are NOT eligible if you have:

• Commercial insurance through an employer
• Insurance through a Federal Employer Plan
• Any private health insurance plan

If you have Medicare Part D or Medicare Advantage, you may still qualify, but you must first be enrolled in the Medicare Prescription Payment Plan before applying to Pfizer PAP.

How to Apply: Step-by-Step

Step 1: Gather Required Documents

Before starting your application, collect the following:

• Proof of Income: One of the following:

  • Previous year's federal tax return (Form 1040 or 1040-EZ, pages 1-2)
  • W-2 forms from your employer
  • Two recent paycheck stubs
  • Social Security, pension, or railroad retirement statements (SSA-1099 or similar)

• Proof of Residency: A document showing your current U.S. address

• Current Prescription: Written by your healthcare provider for Nyvepria

• Insurance Information: Details about your current insurance status (or proof of no insurance)

• Medicare Information (if applicable): Your Medicare ID number and Part D plan details

Step 2: Complete the Enrollment Form

You have two options:

Option A: Apply Online (Recommended)

• Visit Pfizer PAP Connect at www.pfizerpapconnect.com
• Create a new account or log in if you're already enrolled
• Complete the application form online
• Upload your eligibility documents
• Track your application progress in real-time

Option B: Apply by Mail or Fax

• Download the Pfizer Patient Assistance Program Enrollment Form
• Complete all required sections and sign the form
• Gather your supporting documents (see Step 1)
• Mail or fax to:
  • Mailing Address: Pfizer Patient Assistance Program, P.O. Box 66585, St. Louis, MO 63166-6585
  • Fax: 1-877-548-1734

Step 3: Submit Your Application

• If applying online: Submit through Pfizer PAP Connect
• If applying by mail/fax: Include a cover page with your contact information
• Keep copies of everything you submit for your records

Step 4: Wait for Approval

You will be notified of your enrollment status within 2 to 3 weeks of submitting your application. If approved, you'll receive a letter with your enrollment term and instructions on how to receive your medication.

Timeline and Medication Delivery

• Application Processing: 2-3 weeks from submission
• Approval Notification: You'll receive a letter with your enrollment details
• Medication Delivery: Nyvepria will be shipped directly to you or your physician's office, depending on what was arranged
• Enrollment Term: Your approval is valid for a specific period; you may need to reauthorize annually

What If Your Application Is Denied?

If your application is denied, you have options:

1. Ask Why: Contact Pfizer at (800) 505-4426 to understand the reason for denial
2. Reapply: If your circumstances have changed (income, insurance status), you can reapply
3. Consider Alternatives: Ask your doctor about:
   • Neulasta (the original pegfilgrastim product)
   • Other patient assistance programs
   • State pharmaceutical assistance programs
   • Hospital financial assistance programs
   • Clinical trials

Biosimilar Alternatives

If Nyvepria is not available through this program or you're denied, your doctor may consider:

• Neulasta (pegfilgrastim): The original brand-name medication that Nyvepria is based on; may also have its own patient assistance program

Talk to your oncologist about which option is best for your treatment plan.

Important Reminders

• Reauthorization: Your enrollment in the program may need to be renewed periodically. Pfizer will notify you when it's time to reapply.
• No U.S. Citizenship Required: You don't need to be a U.S. citizen, but you must have a U.S. address.
• Confidentiality: Your information is kept confidential and used only to determine eligibility and process your assistance.
• No Cost to Apply: There is no fee to apply for this program.

Contact Information

• Phone: (800) 505-4426 (Monday-Friday, 8 AM-8 PM ET)
• Online: www.pfizerpapconnect.com or www.PfizerRxPathways.com
• Fax: 1-877-548-1734

Disclaimer

This guide provides general information about the Pfizer Patient Assistance Program. Program eligibility, requirements, and benefits may change at any time. For the most current and accurate information, contact Pfizer directly or visit their official website. This guide is not a guarantee of eligibility or approval. Always consult with your healthcare provider about your treatment options and financial assistance programs.