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Nplate

Generic: romiplostim

Manufacturer: Amgen  ·  Program: Amgen SupportPlus Co-Pay Program

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Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Commercial or private insurance (employer-sponsored or self-purchased); uninsured patients referred to independent nonprofit foundations

Residency

US resident

Income Threshold

Up to 500% FPL

Individual Income Limit

$72,900/year

Program Information

Processing Time

1–2 weeks

Delivery Method

shipped to patient

Application Method

Multiple

Indicated for

Immune thrombocytopenic purpura (ITP)

About This Medication

Amgen SupportPlus Co-Pay Program Patient Guide: How to Get Nplate (romiplostim) at Low or No Cost

Nplate (romiplostim) is a prescription medication used to treat low platelet counts in adults and children with immune thrombocytopenia (ITP), a condition where the immune system attacks platelets, leading to increased bleeding risk. The Amgen SupportPlus Co-Pay Program helps eligible patients with commercial insurance reduce out-of-pocket costs for Nplate, potentially paying as little as $0 per dose.[1][2][3]

Who Qualifies for the Program?

This program is designed for patients taking Amgen medications like Nplate who have commercial or private insurance, such as employer-sponsored plans or self-purchased policies. Key eligibility points include:

  • No income eligibility requirement—unlike many assistance programs, your household income does not factor in.[1][3]
  • Must have private or commercial insurance; Medicare, Medicaid, or other government insurance typically do not qualify.[2][6]
  • Approximately 7 in 10 patients pay $0 out-of-pocket, but eligibility criteria and program maximums apply.[1]

Uninsured patients or those with government insurance are referred to independent nonprofit foundations for help.[6]

About Nplate (romiplostim)

Nplate is a man-made protein (thrombopoietin receptor agonist) given as a weekly subcutaneous injection to stimulate platelet production in the bone marrow. It's FDA-approved for:

  • Chronic ITP in adults who have not responded to other treatments like corticosteroids, immunoglobulins, or splenectomy.
  • Chronic ITP in pediatric patients 1 year and older.

Common side effects include headache, joint pain, dizziness, and injection-site reactions. Serious risks involve blood clots, bone marrow changes, or progression to aplastic anemia—discuss with your doctor. Always follow your healthcare provider's instructions for dosing, usually starting at 1-10 mcg/kg weekly, adjusted based on platelet counts.[1][2]

Income Eligibility Breakdown

This program stands out because there are no income thresholds. Eligibility focuses on insurance type rather than finances. Here's a simple table:

Household SizeIncome LimitNotes
IndividualNoneNo income requirements; based on insurance and manufacturer criteria.
CoupleNoneApproximately 7 in 10 patients pay $0 out-of-pocket.
Family of 3NoneProgram maximums apply.
Family of 4+NoneCheck terms at enrollment.

View full terms at AmgenSupportPlus.com/copay.[1][3]

Insurance Requirements

  • Eligible: Commercial/private insurance (e.g., through employer or marketplace).[1][2]
  • Not Eligible: Medicare Part D, Medicaid, VA, Tricare, or other federal programs. Uninsured patients get referrals to nonprofits.[6]
  • The co-pay card covers deductibles, co-insurance, and co-payments for Nplate.[1][3]

Have your insurance card ready when applying.[1]

Step-by-Step Application Process

Enrollment is quick and easy—online or by phone. Follow these 4 simple steps:[4]

  1. Check Eligibility: Visit AmgenSupportPlus.com/copay or call (866) 264-2778 (Mon-Fri, 9 AM-8 PM ET). Confirm your commercial insurance covers Nplate.[1][2]
  2. Enter Personal Information: Provide your name, contact details, date of birth, and insurance info (member ID, group number).[1]
  3. Add Doctor and Site of Care: Include your prescribing doctor's name, contact, and where you'll receive Nplate (e.g., doctor's office, specialty pharmacy).[4]
  4. Get Your Co-Pay Card: If eligible, create an account for virtual card details. You'll receive a welcome letter by mail. Enroll for up to 5 Amgen products at once.[3]

Phone Enrollment: Call (866) 264-2778—staff assist Monday-Friday, 9 AM-8 PM ET.[1][2]

No faxed documents or lengthy forms needed upfront; insurance info is key.[1]

Timeline and Delivery

  • Processing Time: Immediate eligibility check; virtual card available right after enrollment. Welcome letter arrives in days. Full activation may take up to 4 weeks in some cases.[1]
  • Using the Card: Give card details to your doctor's office or specialty pharmacy at fill time. They process it like a credit card to cover your costs.[1][3][7]
  • Delivery of Nplate: Shipped to your home, doctor's office, or pharmacy via your provider—not directly by the program. Program focuses on co-pay reduction.[1]

Refills: Use the card each time; reminders sent for re-enrollment.[8]

Alternatives If Denied or Ineligible

  • Government Insurance/Uninsured: Amgen SupportPlus refers you to independent foundations like Patient Access Network (PAN) Foundation or HealthWell Foundation, which may cover Nplate based on income (often up to 400-500% FPL).[6]
  • Appeal Denial: Contact (866) 264-2778 to review eligibility or explore benefits verification.[5]
  • Other Options: Ask your doctor about generic alternatives (none currently), patient assistance programs via NeedyMeds.org, or state programs. Biosimilars for Nplate are not yet available.
  • Re-enroll: Programs like this often require annual renewal—check mail reminders.[8]

Important Disclaimer

This guide is for informational purposes only and based on program details as of March 2026. Eligibility, benefits, and terms can change—always verify at AmgenSupportPlus.com/copay or by calling (866) 264-2778. This is not medical advice; consult your healthcare provider for treatment decisions. Program maximums apply (e.g., annual caps); see full Terms & Conditions. Amgen reserves the right to modify or end the program.[1][2][3]

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Program information last verified: March 30, 2026

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