Nourianz
Generic: istradefylline
Manufacturer: Kyowa Kirin · Program: Kyowa Kirin Cares Patient Assistance Program
Apply for AssistanceEligibility Criteria
Insurance Requirement
Uninsured patients with no active medical or pharmacy benefit insurance
Residency
US residents
Income Threshold
Up to 400% FPL
Annual gross income ≤ 400% of the federal poverty level
Program Information
Processing Time
2–4 weeks
Delivery Method
shipped to patient or physician office
Application Method
Multiple
Reauthorization
Required — annual
Typically Required Documents
ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.
- Proof of income
- Proof of residency
- Prescription
- Physician verification of medical necessity
Indicated For
Parkinson's disease
About This Medication
# Kyowa Kirin Cares Patient Assistance Program Patient Guide: How to Get Nourianz at Low or No Cost Nourianz (istradefylline) is an FDA-approved medication that helps reduce "off" episodes in adults with Parkinson's disease when used alongside levodopa/carbidopa. The **Kyowa Kirin Cares Patient Assistance Program** offers this drug at low or no cost to eligible uninsured patients with financial need.[1] ## About Nourianz and Why It Matters **Nourianz** is the first and only adenosine A2A receptor antagonist approved in the U.S. for treating "off" episodes in Parkinson's disease (PD). Parkinson's disease causes motor symptoms like tremors, stiffness, and slowness due to low dopamine levels in the brain. Levodopa/carbidopa is a standard treatment, but over time, many patients experience "off" periods when symptoms return between doses. Nourianz works differently—it's a nondopaminergic option taken once daily by mouth. Clinical studies show it reduces "off" time and increases "on" time without causing troublesome dyskinesia (uncontrolled movements). It's available as 20 mg or 40 mg tablets. Always take it as prescribed by your doctor, and discuss any side effects like nausea, dyskinesia, or rare impulse control issues.[1][3] This guide explains how the **Kyowa Kirin Cares** program can make Nourianz accessible if cost is a barrier. The program provides **personalized support**, including access and reimbursement help for patients and caregivers.[1] ## Who Qualifies for the Program? To qualify, you must meet these key criteria: - Be a U.S. resident (proof required). - Have a valid prescription for Nourianz. - Be **uninsured** with no active medical or pharmacy benefit insurance. - Meet **income eligibility** based on household size and federal poverty level (FPL). - Have a doctor verify medical necessity. The program is designed for patients who can't afford their medication otherwise. It's not for those with insurance coverage or high incomes. ## Income Eligibility Breakdown Eligibility is based on **annual gross household income at or below 400% of the federal poverty level (FPL)**. FPL guidelines are updated yearly by the U.S. Department of Health & Human Services. Here's a breakdown for 2026 (check kyowakirincares.com or call for the latest): | Household Size | Max Annual Income (400% FPL) | |---------------|------------------------------| | 1 | $60,320 | | 2 | $81,760 | | 3 | $103,200 | | 4 | $124,640 | | +1 person | Add $21,440 each | *Notes: Income includes all sources before taxes. Some deductions may apply—call (833) 552-2737 for details. Provide recent tax returns, pay stubs, or benefit statements as proof.* ## Insurance Requirements You must be **completely uninsured**—no active medical or pharmacy benefits, including Medicare Part D, Medicaid, or private plans. If you have any coverage, explore other options like manufacturer copay cards first (if available via Kyowa Kirin Cares). The program targets those with zero prescription coverage.[1] ## Step-by-Step Application Process Applying is straightforward with **multiple methods**: phone, download form, or doctor assistance. Here's how: 1. **Get a Prescription**: Ask your neurologist or PD specialist to prescribe Nourianz and complete the physician section verifying medical necessity. 2. **Gather Documents**: - Proof of income (e.g., 2025 tax return, W-2s, pay stubs for 3 months, SSI/SSDI letters). - Proof of residency (utility bill, lease, driver's license). - Prescription copy. - Physician verification form (included in application). 3. **Submit Application**: - **Phone**: Call (833) 552-2737 for help starting. Staff guide you and may process verbally.[1] - **Online/Mail**: Visit kyowakirincares.com to download the form, or request by phone. Mail completed form with documents to the address provided. - Your doctor can submit on your behalf. 4. **Wait for Approval**: Processing time varies (typically 2-4 weeks). You'll get a call or letter. 5. **Receive Medication**: If approved, Nourianz ships **free to your home or doctor's office**. Tips: Apply early. Keep copies of everything. Call if you need language help or have questions. ## Timeline and Delivery - **Submission to Review**: 1-2 weeks for initial check. - **Full Processing**: 2-4 weeks total (call for status). - **Delivery**: Ships directly via mail or to physician—**at no cost**. First shipment covers your needs; refills require reauthorization. **Reauthorization is required** periodically (e.g., every 3-12 months). Your doctor resubmits verification. ## Alternatives if Denied or Ineligible - **Income Too High**: Check state programs, generic options, or patient access networks like NeedyMeds.org or PAN Foundation. - **Insured**: Ask about Kyowa Kirin copay savings (via Kyowa Kirin Cares).[1] - **Other PD Treatments**: Discuss with your doctor—e.g., other "off" reducers like entacapone or opicapone. No biosimilars for Nourianz. - **Appeal Denial**: Call (833) 552-2737 to review reasons and resubmit missing info. - **Low-Cost Clinics**: Federally Qualified Health Centers or PD support groups. ## Important Disclaimer This guide is for informational purposes only and based on program details as of 2026. Eligibility, terms, and FPL levels can change—**always verify with Kyowa Kirin Cares at (833) 552-2737 or kyowakirincares.com**. Not medical advice. Consult your doctor before starting Nourianz. Kyowa Kirin reserves the right to modify or end the program. Word count: 1028.
Program information last verified: March 30, 2026
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