NIVESTYM

Pfizer Patient Assistance Program Patient Guide: How to Get NIVESTYM (filgrastim-aafi) at Low or No Cost

NIVESTYM (filgrastim-aafi) is a biosimilar to NEUPOGEN (filgrastim), used to help reduce the risk of infection during chemotherapy by boosting white blood cell production. The Pfizer Patient Assistance Program offers this medication at no cost to eligible uninsured or government-insured patients with limited income.[1][3]

About NIVESTYM (filgrastim-aafi)

NIVESTYM is an injectable prescription medicine given under the skin (subcutaneously) or into a vein (intravenously). It works like a natural protein in your body called granulocyte colony-stimulating factor (G-CSF), which stimulates your bone marrow to produce more neutrophils—white blood cells that fight infection. Doctors often prescribe it for patients undergoing chemotherapy for cancer, those with severe chronic neutropenia, or after bone marrow transplants to prevent infections.[1][biosimilarAlternatives]

Common uses include:

• Reducing infection risk after chemotherapy.
• Helping stem cell donors produce more cells.
• Treating persistent low white blood cell counts.

Always follow your doctor's instructions on dosing, which is typically based on your body weight and treatment needs. Side effects may include bone pain, fever, or injection site reactions—discuss these with your healthcare provider.[2]

Who Qualifies for the Program?

The Pfizer Patient Assistance Program helps U.S. patients who:

• Have a valid prescription from a U.S.-licensed healthcare provider for outpatient use.[3]
• Meet income guidelines (detailed below).
• Are uninsured or have government insurance like Medicare, Medicaid, CHAMPUS/TRICARE, or Veterans Affairs—but not commercial/private insurance.[3][insuranceRequirements]

Commercially insured patients are not eligible, even if the insurance doesn't cover NIVESTYM. However, commercially insured patients may qualify for separate co-pay assistance programs.[2][3]

Income Eligibility Breakdown

Eligibility is based on household income at or below 600% of the Federal Poverty Level (FPL) for oncology and specialty products like NIVESTYM. This is higher than standard (often 400-500%) due to the product's classification—500% or 600% FPL applies, varying by product and household size.[incomeThresholds]

Use the table below to check approximate guidelines (based on 2026 FPL; confirm current levels at www.pfizerrxpathways.com as they update annually):

Insurance Requirements

• Eligible: Uninsured, Medicare, Medicaid, CHAMPUS/TRICARE, VA.[insuranceRequirements]
• Not Eligible: Any commercial/private insurance (e.g., employer plans), even if NIVESTYM isn't covered.[3][7]
• Medicare Part D patients may need to enroll in the Medicare Prescription Payment Plan for applicable products.[3]

If you have commercial insurance, explore Pfizer's co-pay program instead, which can reduce costs to $0 per treatment (up to $25,000/year).[2]

Step-by-Step Application Process

1. Visit Pfizer RxPathways: Go to www.PfizerRxPathways.com and use the Program Finder. Enter "NIVESTYM" and follow instructions.[1][3]

2. Choose Application Method:

   • Online (Pfizer PAP Connect): For eligible products, complete digitally—upload documents and track status.[1][10]
   • Manual: Download/print enrollment form, fill patient section, have your doctor complete prescriber section.[6]

3. Gather Required Documents:[requiredDocuments][6]

   • Valid U.S. prescription.
   • Proof of income (W-2, 2 recent pay stubs, prior year tax return pages 1-2, SSA-1099).
   • Completed/signed enrollment form (all pages).[7]

4. Submit:

   • Online: Via PAP Connect.[10]
   • Mail: Pfizer Patient Assistance Program, P.O. Box 66585, St. Louis, MO 63166-6585.[6]
   • Fax: 866-470-1748 (prescriber fax with cover page).[6] Do not send medical records or unrequested docs—applications may be rejected.[6]

5. Call for Help: 1-866-706-2400.[3]

Timeline and Delivery

Expect notification within 2-3 weeks of submission. If approved, receive a letter with your enrollment term (typically 1 year) and next steps.[1][6]

Delivery: Medication ships to your physician's office or home.[deliveryMethod] Your doctor coordinates refills.

Alternatives if Denied or Ineligible

• Co-Pay Program (commercial insurance): $0 per treatment, up to $25,000/year. Call 1-877-744-5675.[2][8]
• Biosimilar Alternative: NEUPOGEN (filgrastim)—original reference product, may have similar assistance.[biosimilarAlternatives]
• Other Resources: State programs, NeedyMeds.org, or PAN Foundation. Reapply if circumstances change or check www.PfizerRxPathways.com for updates.[3]
• Reapply: Mark "reapplying" on form if previously enrolled.[7]

Disclaimer

This guide is for informational purposes only and based on program details as of available data. Eligibility, terms, and FPL levels can change—always verify at www.PfizerRxPathways.com or call 1-866-706-2400. Not medical advice; consult your doctor for treatment questions. Pfizer RxPathways and PAP are joint programs of Pfizer Inc. and Pfizer Patient Assistance Foundation.[1][3][6]