Nextstellis

Indicated For

contraception, pregnancy prevention

About This Medication

# Nextstellis (drospirenone and estetrol) Patient Guide: How to Get Nextstellis at Low or No Cost Nextstellis is an oral contraceptive combining **drospirenone** and **estetrol**, manufactured by Mayne Pharma, which offers a **Co-pay Savings Card** program to help eligible patients reduce out-of-pocket costs to as low as $0, primarily for those with commercial insurance.[1][2] This guide explains eligibility, application steps, and alternatives since no traditional income-based patient assistance program with specific income thresholds exists for Nextstellis. ## About Nextstellis **Nextstellis** is a combined oral contraceptive pill used to prevent pregnancy in adults. It contains **drospirenone**, a progestin that helps prevent ovulation and thicken cervical mucus, and **estetrol**, a natural estrogen that supports the contraceptive effect with potentially fewer side effects on certain proteins compared to synthetic estrogens.[1] It's taken daily, typically for 28 days per cycle (24 active pills + 4 inactive). Common side effects may include headache, nausea, breast tenderness, and mood changes—always consult your healthcare provider for personalized advice. Nextstellis is prescription-only and covered by many commercial insurance plans, but costs can be high without assistance.[1] ## Who Qualifies for the Mayne Pharma Co-pay Card? The primary assistance from Mayne Pharma for Nextstellis is the **Co-pay Savings Card**, not a free medication program based on income.[1][2] Qualification focuses on insurance status rather than household income: - **Commercial insurance**: You must have a private/commercial plan (including healthcare exchange plans) that covers Nextstellis.[1][2] - **Pay as low as $0**: Most eligible, covered patients pay $0 copay, though some may have minimal out-of-pocket costs depending on coverage.[1][2][5] - **Exclusions**: - Not valid for government programs like **Medicare, Medicaid, TRICARE, VA, or state assistance**.[1][2][6] - Not for cash-paying (uninsured) patients in standard use, though some Mayne programs allow uninsured for specific drugs.[4] - Not for those with HMO/indemnity plans that fully reimburse or Medicare-eligible in employer/retiree plans.[1] No specific **income thresholds** apply, as this is a copay assistance program, not needs-based PAP. Everyone with qualifying commercial insurance can potentially benefit, with maximum savings limits (details at pharmacy).[1] ## Income Eligibility Breakdown Since the Co-pay Card has **no income requirements**, here's a simple table summarizing eligibility: | Category | Eligible? | Details | |-----------------------|-----------|-------------------------------------------------------------------------| | **Commercial Insurance** | **Yes** | Pay $0 copay if covered; present card at pharmacy.[1][2] | | **Medicare/Medicaid** | **No** | Excluded; see Medicare Part D Alternative below.[1][3] | | **Uninsured/Cash-pay**| **No** | Standard card invalid; check pharmacy discounts.[4] | | **Income-based** | N/A | No FPL limits; open to all qualifying insured patients.[1] | For Medicare patients, a separate **Medicare Part D Alternative Coupon** may apply if your plan denies coverage or costs exceed thresholds (e.g., >$50 for 30-day supply for similar drugs).[3][8] ## Insurance Requirements - **Must have commercial prescription coverage** covering Nextstellis at fill time.[1][2] - **No government insurance**: Cannot use if on Medicare Part D, Medicaid, etc.[1][6] - Pharmacist processes primary insurance first, then applies card as secondary.[6] - For Medicare: Opt-out of Part D for this drug via special coupon (not standard for Nextstellis, but similar to Bijuva/Imvexxy).[3][8] ## Step-by-Step Application 1. **Get Prescribed**: Ask your doctor for Nextstellis if appropriate. 2. **Obtain Co-pay Card**: - Visit **maynepharma.com/co-pay-card/** or search "Nextstellis copay card Mayne Pharma".[1] - Download/print the card or get digitally.[2] - Call **1-888-927-3499 (InfinityRx)** for questions or activation.[1] 3. **Fill Prescription**: - Present valid prescription + card at participating pharmacy. - Pharmacist submits primary insurance claim, then secondary via card (BIN varies; e.g., 610020).[1][6] - If initial claim rejected, resubmit as OCC 3.[6][7] 4. **For Medicare Patients** (if applicable): - Check **maynepharmacoupon.com** for Part D Alternative.[3] - Complete form, opt-out of Part D via letter, use coupon at pharmacy.[8] No mailed applications or documents needed beyond prescription/card—it's instant at pharmacy.[1] ## Timeline and Delivery - **Instant activation**: Card works immediately upon presentation.[1][2] - **Processing**: Pharmacy handles in minutes during fill; reimbursement to pharmacy later.[1][6] - **Delivery**: Standard pharmacy pickup/delivery; no special shipping. - **Expiration**: Cards expire (e.g., 12/31/2025 for some); check current terms as programs change.[1] - **Refills**: Use card each fill; no reauthorization typically needed, but confirm coverage.[1] ## Alternatives if Denied or Ineligible - **Insurance denial**: Ask prescriber for prior authorization or appeal.[7] - **Government insurance**: Explore state PAPs, 340B clinics, or generic alternatives via NeedyMeds.org. - **Uninsured**: Pharmacy discounts, GoodRx, or manufacturer cash-pay options (if available).[4] - **Biosimilars/Generics**: No biosimilars listed; consider other drospirenone/estrogen combos like Yaz (consult doctor).[ ] - **Other Resources**: Partnership for Prescription Assistance (PPARx.org), NeedyMeds, or RxAssist.org for broader PAPs. ## Disclaimer This guide is for informational purposes based on available Mayne Pharma program details as of latest data. Programs can change, expire, or be amended without notice—verify current eligibility/terms at maynepharma.com or by calling 1-888-927-3499.[1] Not health/insurance advice; consult your doctor/pharmacist/insurer. Not valid where prohibited. Mayne Pharma not liable for misuse. Word count: 942.

Program information last verified: March 30, 2026