NERLYNX

Indicated For

HER2-positive breast cancer

About This Medication

# Puma Patient Lynx Patient Assistance Program Guide: How to Get NERLYNX (neratinib) at Low or No Cost This patient-friendly guide explains the **Puma Patient Lynx Patient Assistance Program** from Puma Biotechnology, Inc., designed to help eligible patients access **NERLYNX (neratinib)** tablets free of charge if they meet financial and insurance criteria. NERLYNX is an oral medication used to treat certain types of **HER2-positive breast cancer**, often after prior treatments like trastuzumab, and sometimes for other HER2-positive cancers like cervical cancer[1][4][10]. ## About NERLYNX (neratinib) **NERLYNX** is a prescription medicine taken as **6 tablets (240 mg total) once daily** for up to 1 year in early-stage HER2-positive breast cancer to reduce recurrence risk after surgery and other therapies. It's also used for advanced HER2-positive breast cancer or recurrent/metastatic cervical cancer as second-line or later treatment[4][6][10]. Common side effects include **diarrhea** (managed via Puma's free Antidiarrheal Support Program with vouchers for up to 3 months of free products), nausea, fatigue, and rash. Always take it with food and follow your doctor's dose escalation for the first month using the 133-tablet package[2][6]. Puma Patient Lynx offers nurse support at **1-855-816-5421** (Mon-Fri, 9 AM-6 PM ET) for education and questions[2][7]. ## Who Qualifies for the Program? The **Puma Patient Lynx Patient Assistance Program (PAP)** provides **free NERLYNX** to **uninsured or underinsured patients** who meet **certain financial qualifications** and are **not eligible for other public health insurance programs** (e.g., Medicaid, Medicare Part D if applicable). You must have a valid prescription for NERLYNX from your healthcare provider (HCP). Patients with commercial insurance may qualify for other Puma programs like copay assistance or NERLYNX Quick Start (3-week free supply during delays), but PAP is primarily for those without coverage for NERLYNX[1][3][5]. ## Income Eligibility Breakdown Specific income thresholds (e.g., Federal Poverty Level percentages) are **not publicly detailed**; eligibility is determined case-by-case based on **proof of income** and financial need. Call **1-855-816-5421** for a pre-screening. Here's a general overview: | Household Size | Estimated Threshold | Notes | |---------------|---------------------|-------| | Individual | Meets financial need (TBD) | Based on income proof; no exact FPL % listed[5] | | Couple | Meets financial need (TBD) | Household income considered | | Family of 3 | Meets financial need (TBD) | Includes dependents | | Family of 4+ | Meets financial need (TBD) | Call for details | **Notes**: Provide recent tax returns, pay stubs, or W-2s. Program reserves right to change eligibility[1][5]. ## Insurance Requirements - **Uninsured**: No health insurance at all. - **Underinsured**: Insurance doesn't cover NERLYNX or high copays, and you're not eligible for public programs like Medicaid/Medicare. - **Not eligible** if enrolled in government programs covering NERLYNX or if insurer has final non-coverage denial (other Puma programs may apply)[1][5]. Puma Patient Lynx verifies benefits and assists with prior authorizations/appeals before PAP[1][4]. ## Step-by-Step Application Process 1. **Get Prescribed**: Ask your doctor for NERLYNX. Discuss diagnosis (e.g., HER2+ breast cancer post-trastuzumab)[4]. 2. **Contact Puma Patient Lynx**: Call **1-855-816-5421** (Mon-Fri, 9 AM-6 PM ET) for intake, insurance verification, and PAP eligibility check. Nurses guide you[1][2]. 3. **Download Enrollment Form**: Available at NERLYNX HCP site or via phone. Includes patient demographics, insurance details (attach card copy), clinical info (diagnosis ICD-10 like C50 for breast cancer), allergies, prior treatments[1][4]. 4. **Gather Required Documents**: - **Enrollment Form** (signed by patient and prescriber). - **Proof of Income** (tax returns, pay stubs). - **Proof of Residency** (utility bill, lease). - **Proof of Insurance Status** (insurance card or denial letter; confirm uninsured/underinsured)[1][5]. 5. **Fax Everything**: Send to **844-276-5153**. Incomplete forms delay processing[1][4]. 6. **HIPAA Authorization**: Sign to allow Puma to contact insurers and handle your info[1]. Your specialty pharmacy (e.g., Accredo) coordinates after approval[3][4]. ## Timeline and Delivery **Processing time** not specified; submit complete info to avoid delays. Expect a call from an unrecognized number to confirm prescription and delivery once approved. Medication is **shipped directly to your home** via specialty pharmacy, which also provides refill support and education[3]. For urgent access delays, ask about **NERLYNX Quick Start** (3-week supply + possible 21-day refill for commercial patients pursuing coverage)[9]. ## Alternatives if Denied - **Copay/Coinsurance Program**: For commercial insurance; reduces out-of-pocket costs. - **NERLYNX Quick Start**: Free 3-week supply during prior auth delays[3][9]. - **Prior Auth/Appeal Support**: Puma helps appeal denials[1]. - **Other Resources**: RxAssist.org, NeedyMeds, or state programs. Call Puma for referrals[5][8]. - **Biosimilars/Alternatives**: None listed for NERLYNX[program data]. ## Important Disclaimer This guide is for informational purposes based on available program details as of 2026. **Puma Biotechnology reserves the right to amend, revoke, or rescind the program without notice**. Limitations apply; full terms at 1-855-816-5421. Not a substitute for medical/financial advice—consult your doctor and call Puma Patient Lynx. Eligibility not guaranteed. Puma doesn't guarantee coverage or supply[2][5]. (Word count: 942)

Program information last verified: March 30, 2026