Mytesi
Generic: crofelemer
Manufacturer: Jaguar Health · Program: NapoCares Patient Assistance Program
Apply for AssistanceEligibility Criteria
Insurance Requirement
Uninsured or no insurance coverage
Residency
US resident
Eligibility details not specified; for uninsured patients
Program Information
Processing Time
2–4 weeks
Delivery Method
shipped via specialty pharmacies
Application Method
Multiple
Reauthorization
Required — annual
Typically Required Documents
ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.
- PAP application form
- Letter of Medical Necessity
Indicated For
noninfectious diarrhea in HIV/AIDS patients on antiretroviral therapy
About This Medication
# NapoCares Patient Assistance Program Guide: How to Get Mytesi at Low or No Cost ## About This Program The NapoCares Patient Assistance Program is a free program run by Napo Pharmaceuticals, Inc., the manufacturer of Mytesi (crofelemer). This program helps uninsured and underinsured patients get Mytesi at no cost or reduced cost when they cannot afford their medication. Mytesi is a prescription anti-diarrheal medication used to treat non-infectious diarrhea in people living with HIV/AIDS. If you've been prescribed Mytesi and are struggling to pay for it, this program may be able to help. ## Who Can Apply? You may qualify for the NapoCares Patient Assistance Program if you: - Have a valid prescription for Mytesi from your doctor - Are a U.S. resident - Do not have insurance coverage for Mytesi, OR have insurance but cannot afford your out-of-pocket costs - Do not receive benefits from federally funded health programs (like Medicare, Medicaid, VA, or TRICARE) that cover Mytesi - Meet the income eligibility requirements for your household size (see table below) Note: If you qualify for Medicare, Medicaid, or other federal health programs, you may need to apply through those programs first before applying to NapoCares. ## Income Eligibility Your household income must be at or below the following levels to qualify: | Household Size | Maximum Annual Income | |---|---| | 1 person | Varies | | 2 people | Varies | | 3 people | Varies | | 4 people | Varies | | 5 people | Varies | | 6 people | Varies | | 7+ people | Varies | *Income limits vary and are adjusted periodically. Contact NapoCares directly at (888) 527-6276 for current income thresholds.* ## Insurance Requirements To qualify for NapoCares: - You must be uninsured, OR - Your current insurance does not cover Mytesi, OR - Your insurance coverage is too limited to make the medication affordable If you have Medicare, Medicaid, or other government insurance, you may need to explore those options first. However, if those programs don't cover Mytesi or your costs are still too high, you may still qualify for NapoCares assistance. ## How to Apply: Step-by-Step Instructions **Step 1: Gather Required Documents** Before you start your application, collect the following: - A valid prescription for Mytesi from your doctor - Proof of income for all household members (recent pay stubs, tax returns, or benefit statements from the past 2 months) - Proof of residency (utility bill, lease agreement, or mortgage statement from the past 2 months) - A Letter of Medical Necessity from your doctor explaining why you need Mytesi **Step 2: Choose Your Application Method** You can apply in multiple ways: - **Online**: Visit https://napocares.com to start your application - **Phone**: Call (888) 527-6276 to speak with a program representative who can help guide you through the process - **Mail or Fax**: Ask about mailing in a paper application when you call **Step 3: Complete Your Application** Provide the following information: - Your name, date of birth, and contact information - Your doctor's name and contact information - Your prescription for Mytesi - Your household size and income information - Proof of residency - Your insurance status **Step 4: Submit Your Application** Submit all required documents through your chosen method. Keep copies for your records. **Step 5: Wait for Approval** The program typically processes applications in 4-8 weeks. You should receive notification of approval or denial by mail or phone. **Step 6: Receive Your Medication** Once approved, Mytesi will be shipped to you via a contracted specialty pharmacy distributor. Your medication will be delivered directly to you or your pharmacy. ## Timeline and Delivery **Processing Time**: 4-8 weeks from submission of completed application **Delivery Method**: Your approved Mytesi will be shipped through contracted distributors to a specialty pharmacy. The program will provide you with instructions on how to receive your medication. **Refills**: You will need to apply for reauthorization annually to continue receiving assistance. The program will contact you when it's time to renew. ## Savings Card Option If you don't qualify for the full patient assistance program, you may be eligible for a Mytesi Savings Card that can help reduce your out-of-pocket costs. Visit https://napocares.com to see if you qualify. ## What If Your Application Is Denied? If your application is denied, you have options: - **Ask why**: Contact the program at (888) 527-6276 to understand the reason for denial - **Reapply**: If your circumstances have changed (income, insurance status), you can reapply - **Try a Savings Card**: You may still qualify for discounted pricing through the Mytesi Savings Card - **Contact your doctor**: Ask if there are alternative medications that may be more affordable - **Seek other assistance**: Look into state pharmaceutical assistance programs or organizations like NeedyMeds.org ## Annual Reauthorization Once you're approved for assistance, you must reauthorize your eligibility every year. NapoCares will contact you when it's time to renew. You'll need to provide updated proof of income and residency to continue receiving free or reduced-cost Mytesi. ## Contact Information **NapoCares Patient Assistance Program** - Phone: (888) 527-6276 - Website: https://napocares.com - Hours: Call during business hours for assistance ## Legal Disclaimer This guide is for informational purposes only and does not constitute medical advice or a guarantee of eligibility or approval. Requirements, income limits, and program policies are subject to change. Verify all information directly with NapoCares by visiting https://napocares.com or calling (888) 527-6276. Always consult with your healthcare provider about your treatment options and medication needs.
Program information last verified: March 25, 2026
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