← Medication Database
Other Specialties

Mytesi

Generic: crofelemer

Manufacturer: Jaguar Health  ·  Program: NapoCares Patient Assistance Program

Apply for Assistance

Eligibility Criteria

Insurance Requirement

Uninsured or no insurance coverage

Residency

US resident

Eligibility details not specified; for uninsured patients

Program Information

Processing Time

4–8 weeks

Delivery Method

shipped via specialty pharmacies

Application Method

Multiple

Reauthorization

Required — annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • PAP application form
  • Letter of Medical Necessity

Indicated For

noninfectious diarrhea in HIV/AIDS patients on antiretroviral therapy

About This Medication

# NapoCares Patient Assistance Program: How to Get Mytesi at No Cost ## About This Program The **NapoCares Patient Assistance Program** is designed to provide **Mytesi (crofelemer)** at no cost to eligible patients who cannot afford the medication and have no insurance coverage.[1] Mytesi is a prescription medication that provides symptomatic relief for certain intestinal conditions. This program is administered by Napo Pharmaceuticals, a company focused on developing essential prescription pharmaceuticals.[3] ## Who Qualifies for NapoCares To be eligible for the NapoCares program, you must meet all of the following criteria: - **US Resident**: You must be a US resident (excluding Puerto Rico and other US territories)[1] - **Uninsured or No Coverage**: You have no active insurance coverage or federally funded health benefit options that would allow you to access Mytesi[1] - **Financial Need**: Your annual household income falls below the maximum income threshold adjusted by household size[1] - **Medical Necessity**: Your prescribing healthcare provider has determined that Mytesi is medically appropriate for your condition[1] The program considers your financial situation based on your individual circumstances and, if applicable, your family or household members' combined income.[1] ## Income Eligibility While specific income thresholds are not publicly listed in standard materials, the program uses **income limits adjusted by household size** to determine eligibility.[1] To learn your household's specific income threshold, contact NapoCares directly at **(888) 527-6276** during business hours (Monday-Friday, 9am–5pm ET).[4] When calculating household income, include: - Your income - Income of all household members - Income of any person with legal responsibility for you (if you are a dependent adult)[1] ## Insurance Requirements NapoCares is specifically designed for **uninsured patients**. You are eligible only if you: - Have no active commercial insurance - Have no Medicare coverage - Have no Medicaid coverage - Have no other federally funded health benefit options[1] If you have any form of insurance coverage, you are not eligible for the free medication program. However, Mytesi offers a separate **Copay Savings Card Program** for patients with commercial insurance to help reduce out-of-pocket costs.[4] ## How to Apply: Step-by-Step **Step 1: Obtain the Application Form** Request the NapoCares application from your prescribing healthcare provider or contact NapoCares directly at (888) 527-6276 or napocares@napopharma.com.[1] **Step 2: Complete Your Section** Fill out the patient information section of the application, including: - Your full name and date of birth - Street address, city, state, and ZIP code - Phone number and email address - Authorization for NapoCares to access your medical and financial information[1] **Step 3: Provide Required Documentation** Submit the following with your application: - Completed NapoCares application form (signed by you or your legal representative) - Letter of Medical Necessity from your prescribing healthcare provider[1] **Step 4: Healthcare Provider Signature** Your prescribing healthcare provider must complete and sign the appropriate sections of the application form. Both you and your provider must sign for the application to be considered.[1] **Step 5: Submit Your Application** Send your completed application and documentation to: NapoCares Patient Assistance Program P.O. Box 7613 Overland Park, KS 66207 Or contact them at: - Phone: (888) 527-6276 - Fax: (415) 963-9830 - Email: napocares@napopharma.com[1] ## Timeline and Medication Delivery While specific processing times are not publicly detailed, NapoCares will review your application and contact you or your healthcare provider as needed.[1] Once approved, your medication is delivered through a network of **select specialty pharmacies**.[4] These specialty pharmacies handle the logistics of getting your prescription filled and shipped to you. ## Supply Limits Once approved, you can receive: - **1 initial prescription fill** plus **up to 11 refills** over a 12-month period[1] This means you can receive up to 12 fills (approximately one month's supply each) per year. **Important Timing Note**: If you enroll on or after November 1st, your benefits extend through the remainder of that calendar year plus the entire following calendar year. If you enroll before November 1st, your 12-month period runs through the end of that calendar year only.[1] ## Reauthorization and Renewal You must **reapply annually** if you need additional supplies of Mytesi beyond your initial 12-month period.[1] Contact NapoCares to submit your renewal application each year. ## What Happens If Your Application Is Denied If your application is denied, NapoCares will inform you of the reason. Common reasons for denial include: - Income exceeding the household threshold - Having active insurance coverage - Not meeting medical necessity criteria - Incomplete application or missing documentation If denied, ask NapoCares about: - Whether you can reapply after circumstances change - The Copay Savings Card Program if you have commercial insurance - Specialty pharmacy resources that may offer additional support options ## Additional Support Services Beyond the free medication program, NapoCares offers: - Linkage to in-network specialty pharmacies - Support understanding your insurance coverage - Assistance with prior authorizations and appeals - Mail-order pharmacy support - A patient call center to answer questions[4] ## Contact Information **NapoCares Patient Assistance Program** - Phone: **(888) 527-6276** (Monday-Friday, 9am–5pm ET) - Fax: (415) 963-9830 - Email: napocares@napopharma.com - Mailing Address: P.O. Box 7613, Overland Park, KS 66207 - Website: napocares.com[1][4] **Pharmacy Help Desk** (for prescription processing questions): - Phone: 1-800-800-7364 - Hours: Monday–Friday 8:30am–10pm CT, Saturday 9am–5pm CT[4] ## Important Disclaimer This guide provides general information about the NapoCares Patient Assistance Program based on publicly available materials. Program details, eligibility criteria, income thresholds, and benefits are subject to change at any time without notice. For the most current and accurate information, contact NapoCares directly using the contact information above. This guide is not a guarantee of coverage or approval. Always consult with your healthcare provider and NapoCares representatives regarding your specific situation and eligibility.

Program information last verified: March 25, 2026

Ready to apply for Mytesi assistance?

ProvisionRX manages the complete application process. Start your application in about 15 minutes.

Start My ApplicationBrowse All Medications