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Myfembree

Generic: relugolix, estradiol, and norethindrone acetate

Manufacturer: Myovant Sciences / Pfizer  ·  Program: Myfembree Copay Assistance Program

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Eligibility Criteria

Insurance Requirement

Commercial prescription insurance required; not valid for Medicare, Medicaid, or other government healthcare programs; not valid for cash-paying patients

Residency

US resident, Puerto Rico, or US Territories

Program Information

Processing Time

2–4 weeks

Delivery Method

shipped to patient

Application Method

Online

Reauthorization

Required — calendar year

Indicated For

Moderate to severe pain associated with endometriosis

About This Medication

# Myfembree Copay Assistance Program Patient Guide: How to Get Myfembree at Low or No Cost Myfembree (relugolix, estradiol, and norethindrone acetate) is a prescription medication used to treat moderate to severe symptoms of uterine fibroids in premenopausal women. The **Myfembree Copay Assistance Program**, offered by Myovant Sciences and Pfizer through TrialCard (Mercalis), helps eligible commercially insured patients pay as little as **$5 per prescription** for up to an 84-day supply, with a maximum annual savings of **$5,000 per calendar year**[1][2][4][5]. ## About Myfembree **Myfembree** combines three hormones—relugolix (a GnRH antagonist), estradiol (an estrogen), and norethindrone acetate (a progestin)—to reduce heavy menstrual bleeding and pain caused by uterine fibroids. It's taken as one tablet daily and is typically prescribed for up to 24 months. Common side effects include hot flashes, hair loss, and mood changes; always discuss with your doctor if it's right for you[2][4]. Without assistance, Myfembree can cost over $1,700 per month, making this program a game-changer for many[8]. ## Who Qualifies? This is a **copay assistance program**, not a free drug program, so eligibility focuses on insurance type rather than income. Key requirements include: - **Commercial prescription insurance** (private plans from employers or marketplaces)[2][5]. - A **valid prescription** for an FDA-approved use of Myfembree[2]. - Age **18 years or older**[2]. - Residency in the **U.S., Puerto Rico, or U.S. Territories**[2][5]. **Not eligible:** Patients with Medicare, Medicaid, other government programs, or cash-paying (uninsured) patients[1][2][5][8]. No income requirements apply, making it accessible regardless of household earnings[5]. ## Income Eligibility Breakdown There are **no income thresholds** for this copay program—eligibility is based solely on commercial insurance and residency. Here's a simple table summarizing: | Eligibility Factor | Requirement | Details | |--------------------|-------------|---------| | **Income** | None | Open to all income levels with commercial insurance[5] | | **Insurance** | Commercial only | Excludes Medicare, Medicaid, government programs[2][5] | | **Age** | 18+ | Must be adult resident of U.S./territories[2] | | **Prescription** | Valid for FDA indication | Uterine fibroids treatment[2] | | **Annual Cap** | N/A | Up to $5,000 savings per calendar year[2][4][5] | After reaching $5,000 in savings, you'll pay full out-of-pocket costs until the new year[2]. ## Insurance Requirements **Commercial insurance is required**—this program covers copays, coinsurance, or deductibles for Myfembree prescriptions filled at participating pharmacies[1][2][5]. It's **invalid for**: - Medicare Part D, Medicaid, VA, Tricare, or other federal/state programs[2][5][8]. - Cash-paying patients without insurance[2][5]. - Pharmacy benefit managers or third-party payers cannot assist with enrollment[2]. If your plan covers Myfembree as a **covered benefit**, you may pay $5 per fill; for **non-covered**, similar terms often apply but confirm via the portal[3][10]. Program activates at the pharmacy—present your digital or physical copay card[1]. ## Step-by-Step Application Process Applying is quick and **online**—no paperwork needed upfront[1][5]. Follow these steps: 1. **Visit the enrollment portal**: Go to [https://portal.trialcard.com/myovant/myfembree/copay/](https://portal.trialcard.com/myovant/myfembree/copay/) and click 'Sign up' or 'Get Copay Card'[1][2]. 2. **Provide basic info**: Enter your name, email, phone, date of birth, insurance details, and pharmacy choice. No income proof required[1][5]. 3. **Get your copay card instantly**: Receive a digital card via email or text; print or save to your phone. Physical cards may ship[1]. 4. **Fill prescription**: Take your Rx and copay card to any participating pharmacy. Pay **$5** for up to 84 days (about 3 months)[1][2][5]. 5. **Track benefits**: Log into your portal account to monitor savings used (max $5,000/year, up to 12 fills)[5][10]. Redeem no more than once every 21 days[5]. **Phone support**: Call **(833) 693-3627** (Mon-Fri, 8 AM-8 PM ET) for help enrolling or questions[2][5]. Your doctor or pharmacist can guide you too[6]. ## Timeline and Delivery - **Approval/activation**: Instant upon online enrollment—no processing wait[1]. - **First use**: Use at pharmacy immediately; savings apply per fill[1]. - **Refills**: **Reauthorization required** periodically—program tracks via card; renew online or by phone as needed[program details]. Up to 12 fills/year[5][10]. - **Delivery**: Medication is **shipped to patient**? No—standard pharmacy pickup/delivery; copay card covers at counter[1]. Savings valid through calendar year. Expect seamless use for 84-day supplies every 21+ days[5]. ## Alternatives if Denied or Ineligible If denied (e.g., wrong insurance), explore: - **Switch insurance**: Confirm commercial coverage; appeal denials[5]. - **Other programs**: HealthWell Foundation (income <400% FPG, insured), PAN Foundation, or Pfizer RxPathways for uninsured/low-income[6][7]. Myovant Patient Assistance for uninsured (income-based)[8]. - **Discount cards**: GoodRx/SingleCare for cash-pay (~$1,150/month)[8]. - **Medicare patients**: Extra Help LIS via SSA (1-800-772-1213)[7]. Contact (833) 693-3627 for denial reasons and next steps[5]. ## Important Disclaimer This guide is for informational purposes only and based on publicly available program details as of 2026. Terms can change—always verify at the official portal or by calling (833) 693-3627. Not medical advice; consult your healthcare provider. Program excludes government insurance; max $5,000/year savings. Myovant/Pfizer reserves rights to modify/amend[2][5]. (Word count: 1028)

Program information last verified: March 30, 2026

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