Metopirone
Generic: metyrapone
Manufacturer: HRA Pharma Rare Diseases · Program:
Apply for assistanceFree to apply. Service from $40/month, payable only when your application is ready to submit.
Eligibility Criteria
Insurance Requirement
See program details
Residency
US residency required
Contact Direct Success for financial assistance details
Program Information
Processing Time
2–4 weeks
Delivery Method
shipped to patient via Walgreens Specialty Pharmacy
Application Method
Online
Indicated for
Cushing's syndrome diagnostic, adrenal insufficiency diagnostic
About This Medication
HRA Pharma Patient Assistance Program Patient Guide: How to Get Metopirone (metyrapone) at Low or No Cost
About This Program
The HRA Pharma Rare Diseases Patient Assistance Program helps eligible patients access Metopirone (metyrapone) at reduced or no cost. Metopirone is a diagnostic medication used, in combination with other tests, to diagnose adrenal insufficiency in adults and pediatric patients. If you're struggling to afford this medication, this program may help you get the treatment you need.
About Metopirone (metyrapone)
Metopirone is a specialized diagnostic agent used to evaluate how well your pituitary gland functions. It's typically prescribed as a single-use diagnostic test rather than ongoing therapy. Because it's a rare disease medication, it's often available through specialty pharmacy channels, which is why the assistance program is structured through a specialty pharmacy partner.
Who Qualifies for This Program?
While specific income thresholds are not publicly listed, the program is designed for patients with demonstrated financial need. This typically includes:
- Patients without prescription drug coverage
- Patients with insurance who cannot afford their copayments or coinsurance
- Patients whose insurance denies coverage for Metopirone
- Both insured and uninsured patients experiencing financial hardship
To determine your specific eligibility, you'll need to contact the program directly. Income limits and family size considerations are evaluated on a case-by-case basis.
Income Eligibility
The program does not publish specific income thresholds. However, most pharmaceutical patient assistance programs use federal poverty level (FPL) guidelines, typically ranging from 100% to 400% of FPL depending on family size. The table below shows approximate 2026 federal poverty levels for reference:
| Family Size | 100% FPL | 200% FPL | 300% FPL | 400% FPL |
|---|---|---|---|---|
| Individual | ~$15,000 | ~$30,000 | ~$45,000 | ~$60,000 |
| Couple | ~$20,000 | ~$40,000 | ~$60,000 | ~$80,000 |
| Family of 3 | ~$25,000 | ~$50,000 | ~$75,000 | ~$100,000 |
| Family of 4 | ~$30,000 | ~$60,000 | ~$90,000 | ~$120,000 |
Note: These are estimates. Your actual eligibility depends on your specific circumstances. Contact Direct Success at the number below for exact income thresholds that apply to your situation.
Insurance Requirements
The program serves patients with various insurance situations:
- Uninsured patients: Eligible to apply
- Patients with commercial insurance: Eligible if they cannot afford copayments or if their insurance denies coverage
- Medicare patients: Eligible to apply; the program can work alongside Medicare Part D coverage
- Medicaid patients: Eligible to apply
You do not need to have insurance to qualify, though having insurance information available during application can be helpful.
How to Apply: Step-by-Step
Step 1: Gather Your Information
Before calling, have the following ready:
- Your full name and date of birth
- Household income information
- Number of dependents
- Current insurance information (if applicable)
- Your healthcare provider's name and contact information
- Your prescription details
Step 2: Contact Direct Success
Call 1-844-597-6373 to speak with a program representative. This is the official contact number for HRA Pharma Rare Diseases patient financial assistance.
Hours: Monday-Friday, 8:00 AM - 5:00 PM EST
Step 3: Complete Your Application
The representative will guide you through the application process over the phone. They can help you with pre-screening to determine if you likely qualify before completing the full application.
Step 4: Submit Required Documentation
While specific documentation requirements are not publicly detailed, most programs require:
- Proof of income (recent tax return, pay stubs, or benefit statements)
- Proof of household size (birth certificates or tax documents)
- Insurance information (insurance card or denial letter)
- Prescription from your healthcare provider
The program representative will tell you exactly what documents to submit.
Step 5: Await Approval
Once your application is complete, the program will review your information and notify you of approval status.
Timeline and Delivery
Processing Time: Specific processing timelines are not publicly available. Contact the program at 1-844-597-6373 for an estimate based on your situation.
Delivery Method: Once approved, your Metopirone prescription will be processed and delivered to you through Walgreens Specialty Pharmacy. Here's what to expect:
- Walgreens Specialty Pharmacy receives your prescription from your healthcare provider
- They verify your insurance benefits and obtain any needed authorizations
- A Walgreens representative contacts you to schedule delivery
- Your medication is filled and shipped directly to you
Delivery is typically quick and convenient, though exact timeframes depend on your location and prescription complexity.
What If Your Application Is Denied?
If you don't qualify for the HRA Pharma program, consider these alternatives:
- Medicare Extra Help Program: If you have Medicare Part D, you may qualify for the Low-Income Subsidy (LIS) program, which reduces copayments and deductibles
- Medicare Prescription Payment Plan: Allows you to spread prescription costs over the year instead of paying upfront
- GoodRx: You can use GoodRx discount codes instead of insurance if it results in a lower price
- State Pharmaceutical Assistance Programs: Many states offer additional cost-saving programs for residents
- PAN Foundation: Offers copay assistance grants for certain rare disease medications (up to $11,600 per year for some conditions)
- Discuss with your provider: Your healthcare provider may know of additional resources or alternative diagnostic approaches
Reauthorization and Refills
Since Metopirone is typically used as a single diagnostic test rather than ongoing therapy, reauthorization requirements are minimal. However, if you need additional doses or repeat testing, contact Direct Success at 1-844-597-6373 to discuss your needs.
Important Disclaimer
This guide provides general information about the HRA Pharma Rare Diseases Patient Assistance Program for Metopirone. Program details, eligibility requirements, and benefits may change. For the most current and accurate information, always contact the program directly at 1-844-597-6373 or visit the official Metopirone website. This guide is not a guarantee of eligibility or assistance. Your healthcare provider should always be involved in decisions about your diagnostic testing and medication access.
Program information last verified: March 30, 2026
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