Mepsevii

Indicated For

Mucopolysaccharidosis VII (MPS VII, Sly syndrome)

About This Medication

# UltraCare Patient Assistance Program Guide: Getting Mepsevii at Low Cost ## Overview Mepsevii (vestronidase alfa-vjbk) is a specialized enzyme replacement therapy for mucopolysaccharidosis VII (MPS VII, also called Sly syndrome). Because Mepsevii is an orphan drug for a rare genetic condition, it's extremely expensive. Ultragenyx Pharmaceutical offers the UltraCare Patient Assistance Program to help eligible patients access this life-changing medication at reduced or no cost. ## Who Can Apply? You may qualify for UltraCare if you: - Have been prescribed Mepsevii by your doctor - Are a U.S. resident - Meet income eligibility requirements (see income table below) - Are uninsured, underinsured, or have commercial insurance with high out-of-pocket costs ### Income Eligibility Income limits vary by household size and are updated annually. The program uses federal poverty guidelines as a baseline but often allows income up to 400-500% of the federal poverty level. Contact UltraCare directly at **(844) 887-2273** to confirm your specific income threshold, as limits differ by individual circumstances. ## What the Program Covers **If you're uninsured:** Mepsevii is provided completely free with no out-of-pocket cost. **If you have commercial insurance:** You receive copay assistance, meaning the program pays your insurance copayment or coinsurance. You must be unable to afford your insurance's cost-sharing amounts. **Mepsevii Savings Card:** All eligible patients receive a savings card that can be used at the pharmacy to reduce out-of-pocket expenses. ## Documents You'll Need Prepare the following before applying: 1. **Valid prescription** for Mepsevii from your doctor 2. **Proof of income** (choose one): - Recent tax return (last 2 years) - Recent pay stubs (last 30 days) - W-2 or 1099 forms - Written statement of income from your employer - Proof of benefits (Social Security, disability, unemployment) 3. **Insurance information** (if applicable): - Insurance card copy (front and back) - Insurance member ID and group number 4. **Identification**: Valid photo ID (driver's license, state ID, or passport) ## How to Apply (4 Steps) **Step 1: Get Your Prescription** Your doctor must write a prescription for Mepsevii. Discuss your financial situation with them—they can provide supporting documentation if needed. **Step 2: Contact UltraCare** Call **(844) 887-2273** or visit **https://www.ultracaresupport.com/mepsevii/** to request an application. You can apply by: - Phone (fastest option) - Online application form - Mail or fax **Step 3: Submit Documents** Provide proof of income and your prescription. You can submit documents by: - Phone (read information to representative) - Online portal - Mail or fax **Step 4: Wait for Approval** UltraCare typically reviews applications within 5-7 business days. You'll receive written approval or denial with an explanation. ## After You're Approved **No re-authorization needed.** Once approved, your assistance continues as long as you remain eligible. Annual income re-verification may be required. **Getting your medication:** Your doctor will work with UltraCare and your pharmacy to coordinate delivery. Most patients receive their first dose within 2-3 weeks of approval. **Ongoing support:** UltraCare provides a patient support specialist who helps coordinate your infusions, answer questions, and manage any issues. ## What If You're Denied? If your application is denied, you'll receive a written explanation. Common reasons include: - Income exceeds program limits - Missing required documentation - Ineligible insurance type You can reapply if your circumstances change or if you can provide additional information. ## Important Notes - **Medicare/Medicaid patients:** Contact UltraCare to discuss options, as this program primarily serves uninsured and commercially insured patients. - **No biosimilars:** There are currently no generic or biosimilar versions of Mepsevii. - **Your privacy:** UltraCare maintains strict confidentiality of all patient information. ## Contact Information **UltraCare Patient Assistance Program** - Phone: **(844) 887-2273** (toll-free) - Website: **https://www.ultracaresupport.com/mepsevii/** - Hours: Monday-Friday, 8 AM-8 PM ET Don't let cost prevent you from accessing Mepsevii. Call today to learn if you qualify.

Program information last verified: March 25, 2026