MEKTOVI

Indicated For

Melanoma, Non-Small Cell Lung Cancer

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get MEKTOVI (binimetinib) at Low or No Cost MEKTOVI (binimetinib) is a prescription medication used in combination with BRAFTOVI (encorafenib) to treat certain types of advanced cancer, and the **Pfizer Patient Assistance Program** can provide it free to eligible patients who meet income and insurance criteria. This guide explains everything you need to know about qualifying for and applying to the program in simple terms. It's designed for patients like you navigating cancer treatment costs. Always consult your doctor or healthcare team for personalized advice. ## About MEKTOVI (binimetinib) **MEKTOVI** is an oral targeted therapy that works by blocking enzymes called MEK proteins, which can fuel cancer growth in specific genetic mutations. It's FDA-approved for: - Unresectable or metastatic melanoma with a **BRAF V600E or V600K mutation**. - Metastatic non-small cell lung cancer (NSCLC) with a **BRAF V600E mutation**.[2][5] The standard dose is **45 mg taken orally twice daily**, always with encorafenib (BRAFTOVI) 450 mg once daily, until disease progression or side effects require changes. Common side effects include fatigue, nausea, diarrhea, vomiting, and skin issues—your doctor will monitor these closely.[5] MEKTOVI can be expensive without assistance (often thousands per month), but programs like Pfizer's help make it accessible. This program provides the medication **at no cost** for qualifying patients.[1][3][6] ## Who Qualifies? The **Pfizer Patient Assistance Program** is for patients who: - Are **uninsured** or have **government insurance** (like Medicare or Medicaid) without adequate coverage for MEKTOVI. - Meet strict **income guidelines** based on 400% of the Federal Poverty Level (FPL). - Have a valid prescription for an FDA-approved use.[1][6] You must live in the U.S. and not have commercial insurance covering the drug adequately. If you're underinsured (high copays after exhausting other options), you may qualify after denial from other resources.[3][6] ## Income Eligibility Breakdown Eligibility is based on household income and size, up to **400% of the FPL**. Here's a table with current approximate thresholds (these adjust yearly; confirm with Pfizer as FPL updates annually): | Household Size | Maximum Annual Income | |----------------|-----------------------| | 1 (Individual) | $40,000 | | 2 (Couple) | $54,000 | | 3 | $68,000 | | 4 | $82,000 | *Add about $14,000 per additional family member. These are based on 400% FPL guidelines.*[1] **Notes**: Income includes wages, Social Security, etc. Assets may be reviewed. Dual eligibles (Medicare + Medicaid) or those in the Medicare Donut Hole may still qualify if coverage is inadequate.[1] ## Insurance Requirements - **Uninsured**: Fully eligible if income-qualified. - **Underinsured**: Possible after exhausting copay cards, prior authorizations, or appeals. - **Medicare/Medicaid**: Eligible if no/low coverage for MEKTOVI and after trying Extra Help (Low-Income Subsidy) or state programs. Provide denial letters.[1][3][6] - **Commercial Insurance**: Generally not eligible; try Pfizer's Co-Pay Savings Program first (up to $10,000/year, as low as $0/fill for eligible patients).[4][8] Pfizer Oncology Together helps verify benefits and find options.[3][8] ## Step-by-Step Application Process 1. **Get Your Prescription**: Ask your oncologist for a prescription specifying MEKTOVI for an FDA-approved use. 2. **Gather Documents**: - Proof of income (tax returns, pay stubs, W-2s, SSI/SSDI letters). - Proof of residency (utility bill, lease). - Prescription. - Insurance info (card, denial letter if applicable).[1] 3. **Contact Pfizer**: Call **(855) 242-2038** (Pfizer Oncology Together) to start. They offer multiple methods: phone, download forms online, or provider submission.[3][8] 4. **Submit Application**: Mail/fax/upload with documents. Your doctor may assist. 5. **Wait for Approval**: Processing takes **2-4 weeks**. You'll get a letter.[1] 6. **Receive Medication**: Shipped free to your home or doctor's office.[1] **Tip**: Apply early—don't wait until you run out. Pfizer's team can expedite urgent cases.[3] ## Timeline and Delivery - **Processing**: 2-4 weeks from complete submission.[1] - **Delivery**: Direct ship to patient or provider; one-year supply initially, with reauthorization. - **Reauthorization**: Required annually or if changing providers/dosing. Submit updated income/residency proof; no progressive disease evidence needed per some guidelines.[1][2] Track status by calling (855) 242-2038. ## Alternatives if Denied Don't give up—other options exist: - **Pfizer Co-Pay Program**: For commercial insurance, pay $0-$10 max/fill.[4][8] - **Patient Access Network (PAN)**: Income <400% FPL, Medicare, U.S. resident.[1] - **HealthWell Foundation**: Copays/deductibles, income <400-500% FPL.[1] - **Patient Advocate Foundation**: Insured patients, income <400% FPL, call 866-512-3861.[1] - **Medicaid/Extra Help**: Apply via HealthCare.gov or SSA (1-800-772-1213).[1] - **State Programs**: Check for NSCLC/melanoma-specific aid.[1] Call Pfizer for personalized guidance.[3][6] ## Important Disclaimer This guide is for informational purposes only and based on publicly available program details as of 2026. Eligibility, income limits, and rules can change—**always verify directly with Pfizer at (855) 242-2038**. Not medical advice; consult your healthcare provider. Pfizer disclaims liability for application outcomes. Word count: 1028.

Program information last verified: March 25, 2026