MAVENCLAD

Indicated For

relapsing forms of multiple sclerosis (MS), relapsing-remitting disease, active secondary progressive disease

About This Medication

# MAVENCLAD Patient Guide: How to Get MAVENCLAD at Low or No Cost MAVENCLAD (cladribine) is a short-course oral therapy for adults with relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS (RRMS) and active secondary progressive MS (SPMS).[4][5] This guide explains the MS LifeLines patient support program from EMD Serono, which offers co-pay assistance and free medication for eligible patients.[2][3] ## About MAVENCLAD **MAVENCLAD** is the first and only short-course oral treatment approved by the FDA in March 2019 for adults with certain relapsing MS types.[4][5][8] Unlike daily MS medications, it involves just 20 days of dosing over two years: 3.5 mg per kg body weight total, split into two annual courses of 1.75 mg/kg, each with two treatment weeks.[4][5][8] It works by depleting certain lymphocytes (B and T cells) through DNA synthesis impairment, reducing MS relapses and disease activity.[4][8] Studies show sustained benefits, like cognitive improvement and high rates of No Evidence of Disease Activity (NEDA-3), even years after the initial course.[4][8] It's typically for patients with inadequate response to or intolerance of other MS drugs, not for clinically isolated syndrome (CIS).[4] **Important safety note:** Follow your doctor's instructions for cancer screening, contraception, and blood tests due to risks like infections or lymphopenia.[4][8] ## Who Qualifies for MS LifeLines Assistance? MS LifeLines, sponsored by EMD Serono, provides support including **co-pay help** (as low as $0 for commercial insurance) and **free medication** for eligible U.S. residents (including territories) with relapsing MS starting or taking MAVENCLAD.[2][3] Eligibility depends on financial need, insurance, and other criteria evaluated by the program.[1][3] Key exclusions: Patients on federal/state programs like **Medicare** or **Medicaid** cannot qualify—some limitations apply by law.[3] Uninsured or commercially insured patients may access free meds if they meet financial criteria.[2][3][5] ## Income Eligibility Breakdown Specific income thresholds (e.g., Federal Poverty Level percentages) are not publicly detailed; eligibility is determined case-by-case based on financial and other criteria.[1][3][9] Contact MS LifeLines for a personalized evaluation. | Household Size | Estimated Eligibility Notes | |---------------|----------------------------| | Individual | Financial need required; exact FPL % not specified[1][3] | | Couple | Same; program evaluates household income[1][3] | | Family of 3 | Case-by-case financial review[1][3] | | Family of 4+ | Broader household assessment[1][3] | **Notes:** No fixed FPL percent listed. Programs like EMD Serono's patient assistance offer free meds to those who can't afford them.[9] Commercial insurance often qualifies for co-pay aid.[2] ## Insurance Requirements - **Commercial insurance:** Eligible for MS LifeLines Co-Pay Program—pay $0 co-pay/co-insurance if qualified.[2][3] - **Government insurance (Medicare, Medicaid):** Not eligible for assistance.[3] - **Uninsured:** May get free medication if financially eligible.[2][3][5] Your Patient Support Specialist helps check coverage and benefits.[1][2] ## Step-by-Step Application Process 1. **Contact MS LifeLines:** Call **1-877-447-3243** (Mon-Fri, 8 AM-8 PM ET) or visit **mavenclad.com/support**.[2][3] Speak to a Patient Support Specialist or MS-certified nurse.[2] 2. **Discuss your situation:** Share insurance, income, and MS diagnosis. They'll explain options like co-pay or free medication.[1][2] 3. **Submit enrollment:** Provide required documents (e.g., proof of income, insurance details, prescription). Exact docs vary; specialist guides you.[1] 4. **Eligibility review:** Program evaluates based on criteria.[1][3] 5. **Approval and start:** If approved, get co-pay card or free meds via specialty pharmacy (e.g., limited network like Lumicera).[10][5] Your doctor may also enroll you or coordinate with MS LifeLines.[3] ## Timeline and Delivery Processing time isn't specified but aims to be quick—specialists help navigate promptly.[1] Free medication ships via nationwide delivery from specialty pharmacies, with refill coordination.[5] MAVENCLAD's short course (20 days over 2 years) means delivery aligns with your two treatment weeks per year.[5] Expect home delivery; track via MS LifeLines.[5] ## Alternatives if Denied - **Appeal:** Ask MS LifeLines for reasons and resubmit if possible.[1] - **Foundation grants:** Programs like QuickRx coordinate these.[5] - **Other MS assistance:** Check RxAssist for EMD Serono options or general MS foundations.[9] - **Specialty pharmacies:** Explore co-pay cards or savings.[5][6] - **Doctor discussion:** Ask about MS LifeLines alternatives or other therapies.[1] ## Disclaimer This guide is for informational purposes based on available program details as of public sources. Eligibility, terms, and availability can change—**always verify directly with MS LifeLines at 1-877-447-3243 or mavenclad.com/support**.[1][2][3] Not medical advice; consult your healthcare provider. EMD Serono programs have legal limits, and MAVENCLAD has risks—discuss with your doctor.[3][4]

Program information last verified: March 30, 2026