Lyfgenia

Indicated For

sickle cell disease

About This Medication

# My Bluebird Support Patient Guide: How to Get Lyfgenia at Low or No Cost ## About This Program My bluebird support is a free, personalized patient assistance program offered by bluebird bio to help patients and families access Lyfgenia (lovotibeglogene autotemcel), a one-time gene therapy for sickle cell disease. This program is designed to support you throughout your treatment journey, from initial consideration through treatment and beyond. ## What is Lyfgenia? Lyfgenia is a one-time ex-vivo gene therapy approved by the FDA for treating sickle cell disease in patients ages 12 and older with a history of vaso-occlusive events (VOEs)—painful episodes that are a hallmark of sickle cell disease. As a gene therapy, Lyfgenia works differently from traditional medications and offers the potential for long-term, transformative benefits in reducing or eliminating pain crises. The list price for Lyfgenia is $3.1 million. However, bluebird bio recognizes that cost can be a significant barrier to accessing this life-changing treatment, which is why my bluebird support exists to help connect patients with financial assistance options. ## Who Qualifies for My Bluebird Support? My bluebird support is available to eligible residents of the United States and its territories who are considering Lyfgenia treatment. You do not need to have insurance or meet specific income thresholds to enroll in my bluebird support—the program is designed to help all patients explore their options. However, specific financial assistance programs may have income eligibility requirements. Your dedicated Patient Navigator will review your individual situation and help determine which financial assistance options may be available to you. ## Income Eligibility and Financial Assistance While my bluebird support itself has no income restrictions, the financial assistance programs that your Patient Navigator can connect you with may have specific eligibility criteria. These programs are designed to help patients who cannot afford their treatment costs. Your Patient Navigator will: - Conduct a benefits verification to outline your full range of coverage and costs - Review available financial assistance options - Determine which programs you may qualify for based on your individual circumstances - Help you understand your out-of-pocket costs ## Insurance Requirements You do not need to have insurance to access my bluebird support or to be considered for Lyfgenia treatment. However, if you have insurance coverage, your Patient Navigator can help you navigate the authorization process and understand your coverage. Bluebird bio has entered into outcomes-based agreements with major payers, and discussions are underway to ensure coverage under Medicaid. Your Patient Navigator can provide information about coverage options specific to your insurance situation. ## How to Apply: Step-by-Step Process ### Step 1: Enroll in My Bluebird Support Enrollment is simple and free. Complete the Program Enrollment Form available at mybluebirdsupport.com or contact the program directly: - **Phone:** 1-833-888-6378 - **Email:** mybluebirdsupport@bluebirdbio.com Enrollment does not obligate you to move forward with treatment—it simply starts the conversation with a Patient Navigator. ### Step 2: Connect with Your Patient Navigator Once enrolled, you will be assigned a dedicated Patient Navigator—a patient support specialist trained to help you through the decision-making process. Your Patient Navigator will: - Answer your questions about Lyfgenia and gene therapy - Help locate Qualified Treatment Centers (QTCs) in your area - Conduct benefits verification - Connect you with financial assistance programs - Provide education about the treatment process - Support you through the insurance authorization process ### Step 3: Explore Financial Assistance Options Your Patient Navigator will review available financial assistance programs and help determine your eligibility. Be prepared to discuss your financial situation, insurance coverage, and any barriers to accessing treatment. ### Step 4: Work with Your Care Team If you decide to move forward with treatment, you will work with your care team at a Qualified Treatment Center (QTC)—a specialized hospital trained to administer bluebird bio gene therapies. The treatment process involves three main phases: 1. **Consultation** - Meet with your treatment team 2. **Apheresis** - Cell collection procedure 3. **Treatment** - Gene therapy administration ## Timeline and Delivery The specific timeline for approval and treatment varies based on individual circumstances, insurance authorization, and your treatment center's schedule. Your Patient Navigator will provide guidance on what to expect and help coordinate the authorization process with your insurance company. Lyfgenia is only available through a national network of Qualified Treatment Centers. Your Patient Navigator will help you locate a QTC near you and coordinate your care. ## What Happens If Your Application Is Denied If you are denied financial assistance through one program, your Patient Navigator can help you explore alternative options. My bluebird support is committed to working with you to find solutions that make treatment accessible. Do not hesitate to discuss your specific barriers with your Patient Navigator—they may be able to identify additional resources or programs you qualify for. ## Important Considerations - **No obligation to treat:** Enrolling in my bluebird support does not commit you to treatment. It is simply a way to get information and support as you make decisions with your doctor. - **Personalized support:** Every patient's situation is unique. Your Patient Navigator will tailor their assistance to your specific needs and circumstances. - **Ongoing support:** My bluebird support is available throughout your treatment journey, not just during the application process. ## Contact Information **My Bluebird Support:** - **Phone:** 1-833-888-6378 - **Email:** mybluebirdsupport@bluebirdbio.com - **Website:** mybluebirdsupport.com **For Cancer-Related Concerns:** - **Phone:** 1-833-999-6378 ## Disclaimer This guide provides general information about my bluebird support and Lyfgenia. It is not a substitute for medical advice or professional consultation. Please speak with your healthcare provider about whether Lyfgenia is appropriate for your individual situation. Financial assistance eligibility and program details are subject to change. For the most current and accurate information, contact my bluebird support directly using the contact information provided above.

Program information last verified: March 30, 2026