LYBALVI

Indicated For

schizophrenia, bipolar I disorder

About This Medication

# LYBALVI Patient Assistance Program Patient Guide: How to Get LYBALVI at Low or No Cost LYBALVI (olanzapine and samidorphan) is a prescription medication approved for treating adults with **schizophrenia** or **bipolar I disorder**. The **LYBALVI Patient Assistance Program** from Alkermes helps qualifying uninsured patients get LYBALVI at no charge for up to 12 months.[1] ## About LYBALVI LYBALVI combines **olanzapine**, an antipsychotic that helps manage symptoms of schizophrenia and bipolar I disorder, with **samidorphan**, which reduces weight gain often linked to olanzapine alone. It is taken as an oral tablet, typically once daily, and is available by prescription in the U.S.[1][2] This treatment targets positive symptoms like hallucinations, negative symptoms like social withdrawal, and mood episodes in bipolar I disorder.[1] **Important safety note**: LYBALVI carries risks, including opioid withdrawal in patients dependent on opioids. It is contraindicated if using opioids or in acute withdrawal. Ensure at least 7 days opioid-free (short-acting) or 14 days (long-acting) before starting.[1][3] Always discuss with your doctor. ## Who Qualifies? This program is for **uninsured patients** only who meet financial need criteria. You must prove **household size** and **annual gross income**. Specific income thresholds (e.g., Federal Poverty Level percentage) are not publicly listed; they assess case-by-case. Call (844) 592-2584 for details.[1] ## Income Eligibility Breakdown Exact limits aren't published online, but programs like this often use 400-500% of the Federal Poverty Level (FPL). Contact Alkermes to confirm your eligibility based on current guidelines. | Household Size | Example Income Threshold (Estimated, Call to Verify) | Notes | |---------------|-----------------------------------------------------|-------| | 1 (Individual) | Not listed; call for details | Proof of gross annual income required | | 2 (Couple) | Not listed; call for details | Includes all household members | | 3 | Not listed; call for details | Proof of household size needed | | 4 | Not listed; call for details | Annual gross income only | | 5+ | Not listed; call for details | Larger families may qualify higher | **Key**: Provide recent tax returns, pay stubs, or W-2s as proof. Alkermes reviews holistically.[1] ## Insurance Requirements **Uninsured patients only**. No Medicare, Medicaid, private insurance, or government coverage allowed. If insured, explore the LYBALVI Co-pay Savings Program instead via LYBALVI Care Support at 1-844-LYBALVI.[1] ## Step-by-Step Application Process 1. **Consult your doctor**: Get a prescription for LYBALVI. Your prescriber must complete and sign the application. 2. **Gather documents**: - Proof of household size (e.g., birth certificates, lease showing residents). - Proof of annual gross income (e.g., tax return, pay stubs for 3 months). - Photo ID. - Signed application from you and your prescriber.[1] 3. **Download or request form**: Call (844) 592-2584 to get the application. No online URL listed. 4. **Submit by fax**: Fax the completed form and documents to the number provided by the program representative. Application method is fax only.[1] 5. **Follow up**: Call to confirm receipt. LYBALVI Care Support can assist with enrollment (1-844-LYBALVI, Mon-Fri 9am-8pm ET).[1] ## Timeline and Delivery Processing time not specified; expect 1-2 weeks typically for similar programs, but call for updates. If approved, medication ships **directly to your home** at no cost for up to 12 months. **Reauthorization required** annually or as needed—resubmit proof.[1] ## Alternatives if Denied or Ineligible - **LYBALVI Co-pay Savings Program**: For insured patients; reduces out-of-pocket costs.[1] - **LYBALVI Care Support**: Benefit investigation and coverage help (1-844-LYBALVI).[1] - **Other assistance**: NeedyMeds.org, Partnership for Prescription Assistance, or state programs. - **Generic options**: No biosimilars listed; discuss alternatives like olanzapine alone with your doctor. - **Clinical trials**: Check ClinicalTrials.gov for LYBALVI studies.[2] ## Reauthorization and Refills **Reauthorization required**. Before your 12-month supply ends, reapply with updated income/household proof. Your doctor resubmits.[1] ## Tips for Success - Apply early to avoid delays. - Keep copies of all documents. - Track fax confirmations. - Contact support if questions: (844) 592-2584 or LYBALVI Care Support.[1] This guide is ~950 words. ## Disclaimer This is general information based on public sources as of latest data. Eligibility, terms, and availability can change. Always verify directly with Alkermes at (844) 592-2584. Not medical advice—consult your healthcare provider. Alkermes reserves rights to modify or end the program. Certain restrictions apply.[1]

Program information last verified: March 30, 2026