Lorbrena

Indicated For

ALK-positive NSCLC, ROS1-positive NSCLC

About This Medication

# Pfizer Patient Assistance Program Patient Guide: How to Get Lorbrena (lorlatinib) at Low or No Cost Lorbrena (lorlatinib) is a prescription medication used to treat certain types of advanced lung cancer, specifically anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) in adults whose disease has progressed after prior treatments. The **Pfizer Patient Assistance Program** offers **Lorbrena for free** to eligible patients who meet income, residency, and insurance criteria, helping those facing high costs get access without financial strain[1][3]. ## Who Qualifies for the Program? This program is designed for patients struggling to afford their medication due to limited income or lack of insurance coverage. Key eligibility factors include: - **Residency**: You must live in the United States, Puerto Rico, or U.S. Virgin Islands[4]. - **Age and Treatment Setting**: Be 18 years or older and treated in an outpatient setting by a U.S.-licensed healthcare provider[6]. - **Income Limits**: Household income at or below **400% of the Federal Poverty Level (FPL)**, adjusted for family size. This threshold ensures the program targets those with the greatest financial need[program details][1]. - **Insurance Status**: Uninsured, or enrolled in government insurance like Medicare or Medicaid but not qualifying for other resources. **Commercially insured patients are not eligible** for this free medicine program[program details][3]. **Important Note**: Before enrolling, exhaust other options like Medicare Extra Help (Low-Income Subsidy), Medicaid, or co-pay assistance programs. Pfizer Oncology Together can help check these first[1][3]. ## About Lorbrena (lorlatinib) **Lorbrena** is an oral kinase inhibitor that targets specific genetic mutations in lung cancer cells, blocking enzymes that allow cancer to grow and spread. It's typically taken as tablets once daily, with or without food, but always follow your doctor's instructions. Common side effects include fatigue, swelling, mood changes, high cholesterol, and lung issues—report any severe symptoms immediately. This program provides the medication **free of charge** for eligible patients, covering a supply based on your prescription needs[1]. Always discuss with your oncologist how Lorbrena fits your treatment plan. ## Income Eligibility Breakdown Eligibility hinges on your total household income compared to the **Federal Poverty Level (FPL)**. The program uses **400% of FPL**, which changes annually. Here's a table with 2026 estimates (check www.PfizerRxPathways.com for exact current figures, as they adjust for family size and location): | Household Size | Annual Income Limit (400% FPL) | |----------------|-------------------------------| | 1 (Individual) | $60,240 | | 2 (Couple) | $81,760 | | 3 | $103,280 | | 4 | $124,800 | *Add about $21,520 per additional family member. Income includes wages, Social Security, pensions, etc. Provide proof like tax returns, W-2s, or pay stubs[4][9][program details].* ## Insurance Requirements - **Uninsured**: Fully eligible if other criteria are met. - **Government Insured (Medicare, Medicaid)**: Eligible if you don't qualify for coverage through these programs or other aid like Extra Help. Pfizer can verify this[3][program details]. - **Commercially Insured**: **Not eligible**—use Pfizer's co-pay savings card instead via Pfizer Oncology Together[1][5]. Patients must submit copies of insurance cards (front and back) and may need to show denial of coverage[6]. ## Step-by-Step Application Process Applying is straightforward with **multiple methods**: online, phone, or mail/fax. Work with your doctor[2]. 1. **Check Eligibility**: Call (800) 505-4426 or 1-844-989-PATH (7284) for a free consultation with a Pfizer Medicine Access Counselor[4][program details]. 2. **Gather Documents**: - Proof of income (e.g., 1040 tax pages 1-2, W-2, pay stubs, SSA-1099)[9]. - Proof of residency (e.g., utility bill). - Valid prescription signed by your doctor[program details][6]. - Insurance cards or denial letters. 3. **Start Application**: - **Online**: Visit www.PfizerRxPathways.com, use Program Finder, enter 'Lorbrena,' and complete via Pfizer PAP Connect[2]. - **Phone**: Call (800) 505-4426 to start[program details]. - **Mail/Fax**: Download form from PfizerRxPathways.com, have doctor complete sections, mail to P.O. Box 66585, St. Louis, MO 63166-6585 or fax 866-470-1748[9]. 4. **Sign and Submit**: Patient and doctor sign; include all docs. Opt for electronic income verification if available[6]. 5. **Wait for Approval**: Notified in **2-3 weeks**[2][4]. ## Timeline and Delivery - **Processing**: 2-3 weeks for decision[2]. - **Delivery**: Medicine **shipped directly to your home** free of charge[program details]. - **Supply Duration**: Typically 1-3 months per shipment; **reauthorization required** for refills—resubmit proof as needed[3][program details]. ## Alternatives if Denied or Ineligible - **Co-Pay Assistance**: For commercially insured, use Pfizer Oncology Together co-pay card (reduces out-of-pocket to $0 for many)[1][5]. - **Other Resources**: Apply for Medicaid/Extra Help; Pfizer helps with benefits verification, prior authorizations[3]. - **Patient Starter Kit**: Register on lorbrena.com for support[1]. - **No Biosimilars**: Lorbrena has no listed alternatives in this program[program details]. Contact Pfizer Oncology Together at 1-877-744-5675 for personalized help. ## Disclaimer This guide is for informational purposes only and based on program details as of March 2026. Eligibility rules, income limits, and processes can change—always verify at www.PfizerRxPathways.com or by phone. Not medical advice; consult your healthcare provider. Pfizer reserves the right to modify or end the program. Free medicine provided via Pfizer Patient Assistance Foundation[3][7]. (Word count: 1028)

Program information last verified: March 30, 2026