Lokelma

Indicated For

hyperkalemia

About This Medication

# AstraZeneca Patient Assistance Program Guide: How to Get Lokelma at Low or No Cost Lokelma (sodium zirconium cyclosilicate) is a prescription medication used to treat high potassium levels in the blood, a condition known as hyperkalemia. This guide explains how to access AstraZeneca's patient assistance program (PAP), which can provide Lokelma for free or at a very low cost to eligible patients. If you're struggling with the cost of your medication, this program might be able to help. We'll cover everything from eligibility to the application process in simple terms. ## About Lokelma Lokelma works by binding to excess potassium in your digestive system, helping your body remove it through stool. It's typically taken as a powder mixed with water, once daily for ongoing treatment or as needed for acute episodes. Common side effects include constipation, nausea, or stomach pain, but it's generally well-tolerated. Always follow your doctor's instructions and report any unusual symptoms. Hyperkalemia can be serious, especially if you have kidney disease, heart failure, or diabetes. Lokelma is not a cure but helps manage potassium levels alongside diet changes and other treatments. If you're prescribed Lokelma, affordability shouldn't stand in the way of your health. ## Who Qualifies for the Program? AstraZeneca's PAP is designed for patients who are uninsured, underinsured, or facing financial hardship. Key qualifications include: - **US residency**: You must live in the United States (including territories). - **Prescription requirement**: A valid prescription from a US-licensed doctor. - **Income limits**: Household income typically up to 400-500% of the Federal Poverty Level (FPL), though exact thresholds vary and are not publicly detailed—contact the program for your situation. - **Age**: Open to all ages, but Medicare patients may have separate options (see below). The program prioritizes those without prescription insurance or with high copays/deductibles. It's not for patients with government insurance like Medicare Part D in most cases, but exceptions exist. ## Income Eligibility Breakdown Income eligibility is based on household size and annual gross income compared to the Federal Poverty Level (FPL). AstraZeneca does not publish fixed thresholds online, but programs like this often cover up to 400-600% FPL. Use the table below as a general guide (2026 FPL estimates; verify current figures at ASPE.hhs.gov). | Household Size | 100% FPL | 400% FPL | 500% FPL | |---------------|----------|----------|----------| | 1 (Individual) | $15,060 | $60,240 | $75,300 | | 2 (Couple) | $20,440 | $81,760 | $102,200| | 3 | $25,820 | $103,280| $129,100| | 4 | $31,200 | $124,800| $156,000| **Notes**: Add ~$5,380 per additional person. Income includes wages, Social Security, etc. Assets may be considered. Call to confirm your eligibility—many qualify even above these levels if medically necessary. ## Insurance Requirements - **Uninsured**: Fully eligible. - **Private insurance**: Eligible if copays exceed 10% of income or if denied coverage. - **Medicare**: Generally ineligible for free drug, but AstraZeneca offers a Medicare Extra Help bridge or copay cards. Check Medicare Part D low-income subsidy first. - **Medicaid**: Usually ineligible. Provide proof of insurance status and any denial letters. ## Step-by-Step Application Process 1. **Get your prescription**: Ask your doctor to prescribe Lokelma and complete the PAP form (available online or by phone). 2. **Gather documents**: Proof of income (tax returns, pay stubs, SSI letters), prescription, doctor's info, proof of residency/insurance. 3. **Apply**: Call 1-800-424-3727 (AstraZeneca PAP hotline) or download the form from astrazeneca-us.com/access. Submit via mail, fax, or online portal. 4. **Doctor involvement**: Your prescriber must sign and submit clinical info. 5. **Wait for approval**: Processing takes 2-4 weeks. 6. **Receive medication**: Shipped to your home or doctor's office. Applications are free and confidential. ## Timeline and Delivery - **Submission to review**: 1-2 weeks. - **Approval/denial notice**: 2-4 weeks total. - **Delivery**: 7-10 business days after approval via mail (free shipping). First shipment covers 1-3 months; refills automatic. Track status by calling the hotline. ## Alternatives if Denied - **Appeal**: Submit additional docs within 30 days. - **Copay savings cards**: AstraZeneca's Lokelma Savings Card for commercially insured (up to $225/month off). - **Other PAPs**: Partnership for Prescription Assistance (pparx.org) or NeedyMeds.org. - **Generic alternatives**: None yet; closest is sodium polystyrene sulfonate (Kayexalate), but less preferred. - **State programs**: Check your state's drug assistance. - **Patient Access Network (PAN) Foundation**: Grants for copays. ## Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Program details can change; always verify with AstraZeneca at 1-800-424-3727 or their website. Not medical advice—consult your doctor. AstraZeneca reserves the right to modify eligibility. Word count: 942.

Program information last verified: March 30, 2026