Leqembi

Indicated For

Early Alzheimer's disease, mild cognitive impairment (MCI), mild dementia

About This Medication

# LEQEMBI Companion Program Patient Guide: How to Get Leqembi (lecanemab-irmb) at Low or No Cost Leqembi (lecanemab-irmb) is an FDA-approved intravenous infusion treatment for early Alzheimer's disease, specifically for patients with mild cognitive impairment or mild dementia due to Alzheimer's, confirmed by amyloid pathology.[1][2] The **LEQEMBI Companion program**, sponsored by **Eisai**, offers multiple support options including the **Copay Assistance Program** for commercially insured patients, the **Patient Assistance Program (PAP)** for uninsured or underinsured patients with financial need, and the **Temporary Supply Program** to bridge coverage gaps.[1][3][5] ## About Leqembi and Why Assistance Matters Leqembi works by targeting amyloid beta plaques in the brain, a key hallmark of Alzheimer's disease, to slow cognitive decline in its early stages.[1] Administered every two weeks via IV infusion in a clinical setting, treatment costs can exceed $26,000 annually without support, making Eisai's programs crucial for access.[3][7] These programs help reduce or eliminate out-of-pocket expenses, ensuring more patients can start and maintain therapy.[2] ## Who Qualifies? Eligibility varies by program: - **Copay Assistance Program**: For **commercially insured** patients (not Medicare, Medicaid, or government insurance). Covers up to **$10,000 per calendar year** for deductibles, copays, and coinsurance, potentially reducing costs to **$0 per treatment**.[3][5][7] - **Patient Assistance Program (PAP)**: For **uninsured** or **insured patients denied coverage** (after first-level appeal) who demonstrate **financial need**. Provides **Leqembi at no cost** with a valid prescription for FDA-approved use.[3][5][6] - **Temporary Supply Program**: For **commercially insured** new patients awaiting coverage decisions (after 5+ business days and first-level appeal). Offers up to **75 days of free supply**.[5][6] **Income eligibility** details for PAP are not publicly specified but require proof of financial hardship; call 1-833-453-7362 for personalized assessment.[1][3] No exact FPL percentages are listed, but programs target those unable to afford treatment.[5] ## Income Eligibility Breakdown | Household Size | Estimated Threshold | Notes | |---------------|---------------------|-------| | Individual | Financial need-based (call for details) | Proof of income/hardship required for PAP[3][5] | | Couple | Financial need-based (call for details) | Uninsured/underinsured only[3] | | Family of 3 | Financial need-based (call for details) | Coverage denial appeal needed if insured[5] | | Family of 4+ | Financial need-based (call for details) | Eisai assesses case-by-case[6] | Contact the program for precise criteria, as they evaluate holistically.[1] ## Insurance Requirements - **Commercial insurance** required for Copay and Temporary Supply Programs; government insurance (e.g., **Medicare Part B**, Medicaid) disqualifies from Copay.[3][5] - PAP accepts uninsured or those with denied coverage (submit appeal documentation).[3][6] - Program navigators help verify coverage and out-of-pocket estimates.[2] ## Step-by-Step Application Process 1. **Discuss with your healthcare provider**: Talk about Leqembi and program enrollment at your next visit. They select suitable programs and complete their form sections.[1] 2. **Complete enrollment**: Fill patient sections (signatures required). Do this in-office, digitally at **LEQEMBIEnrollment.com**, or with provider help.[1][4] 3. **Submit**: Provider faxes form to 1-833-770-7017. For Copay, expect a **16-digit virtual debit card** upon approval.[1][5][7] 4. **Call for support**: Dial **1-833-453-7362 (1-833-4-LEQEMBI)** Monday-Friday 8 AM-8 PM ET for navigators to assist.[1][7] 5. **Await contact**: Program reaches out with next steps and welcome.[1] For Copay claims, submit **CMS-1500/UB-04 form** and **EOB** within 365 days of treatment.[3][6] ## Timeline and Delivery - **Processing**: Varies; Temporary Supply acts quickly for urgent needs. Copay covers retroactively up to 180 days pre-enrollment.[5] - **Approval timeline**: Not specified; call for status updates. Once approved, PAP delivers free drug to pharmacy/specialty site; Copay card activates fast.[1][5] - **Delivery**: Leqembi is infused clinically. Programs coordinate with providers/pharmacies; no direct patient shipping.[3] ## Alternatives if Denied - Appeal insurance denial and reapply for PAP/Temporary Supply.[5] - Explore advocacy groups for Alzheimer's support listed in program resources.[1] - Check **biosimilar alternatives**: None available currently.[ ] - Contact navigators for other Eisai programs or general assistance resources.[2] ## Reauthorization and Refills Ongoing eligibility reviewed; PAP/Copay require annual recertification. Provider resubmits as needed. Copay resets yearly up to $10,000.[3][5] ## Required Documents - Valid Leqembi prescription. - Proof of income/insurance (for PAP). - EOB/claims forms (for Copay). - Provider signatures.[1][3][5] ## Disclaimer This guide is for informational purposes based on available program details as of 2026. Eligibility, terms, and benefits can change; Eisai reserves the right to amend/revoke.[5][6] Not a guarantee of coverage. Consult your provider and call 1-833-453-7362 for latest info. Always review full Prescribing Information and terms at EisaiPatientSupport.com/LEQEMBI.[1] (Word count: 942)

Program information last verified: March 30, 2026