Krystexxa

Indicated For

chronic refractory gout

About This Medication

# Amgen By Your Side Patient Guide: How to Get Krystexxa at Low or No Cost Krystexxa (pegloticase) is a prescription medication used to treat chronic gout in adults who haven't responded well to other treatments like xanthine oxidase inhibitors, or for whom those drugs aren't suitable.[1][2][4] The **Amgen By Your Side** program offers financial support, co-pay assistance, and personalized help to make treatment more affordable, especially for commercially insured patients aiming for $0 out-of-pocket costs.[1][2] ## About Krystexxa and Why You Might Need It Chronic gout causes painful flares from high uric acid levels building up as crystals in your joints. Standard oral medications like allopurinol or febuxostat (xanthine oxidase inhibitors) work for many, but if you've tried the highest appropriate dose and your uric acid levels stay high (above 6 mg/dL), or if those drugs cause issues, Krystexxa may be recommended.[1][4] It's given as an **intravenous (IV) infusion** every two weeks in a healthcare setting, like a doctor's office, hospital, or infusion center—not typically at home unless assessed safe by professionals.[3][4] **Important safety notes**: Before starting, get screened for G6PD deficiency, as it's contraindicated in those patients due to risk of serious reactions. You'll be premedicated with antihistamines and corticosteroids to reduce anaphylaxis risk, and uric acid levels must be monitored before each dose—if they rise above 6 mg/dL twice in a row, treatment stops.[1][4] Always report symptoms like breathing trouble, swelling, or hives immediately.[9] Krystexxa isn't for asymptomatic high uric acid; it's for uncontrolled gout symptoms.[4] Talk to your doctor about risks, benefits, and if it's right for you. ## Who Qualifies for Amgen By Your Side Assistance? This program primarily helps **commercially insured patients** with co-pay support for the drug and infusion costs, potentially reducing out-of-pocket to $0.[2] It's available for **94% of commercial lives** after appropriate prior treatments.[2] Uninsured patients or those needing more help should contact the program for options, including independent foundations.[1][2][7] **Medicare patients**: 100% of Medicare Fee-For-Service lives may be eligible, but no national coverage decisions exist—your doctor or the program can check.[2] Government-insured (Medicare/Medicaid) may access copay cards or foundations like Assistance Fund or HealthWell.[7] No strict income thresholds are listed; eligibility focuses on insurance status and financial need. Contact **(877) 633-9521** for personalized screening.[2][3] ## Income Eligibility Breakdown Amgen By Your Side doesn't publish fixed **Federal Poverty Level (FPL)** cutoffs like some programs. Instead, support tiers by insurance: | Patient Situation | Assistance Available | |--------------------------------|--------------------------------------------------------------------------------------| | **Commercially Insured** | $0 co-pay for medication + infusion via Amgen Commercial Co-Pay Program.[2] | | **Uninsured** | Explore options with Amgen By Your Side; possible foundation support.[1][2][7] | | **Insured, Not Co-Pay Eligible**| Independent foundations; call (877) 633-9521 for referrals.[2] | | **Medicare/Medicaid** | Copay cards/foundation aid possible (e.g., Assistance Fund: Gout).[7] | Notes: No income caps specified; case-by-case for uninsured. Third-party help like AmeriPharma may secure additional funding.[6][7] ## Insurance Requirements **Primarily for commercial insurance**—co-pay program covers most.[2] Uninsured: Contact for alternatives.[1] Medicare: Eligible but verify coverage, as no blanket policy exists.[2] Your Patient Access Liaison (PAL) investigates benefits upon enrollment.[3][8] ## Step-by-Step Application Process 1. **Get Prescribed**: Discuss with your rheumatologist if you've failed standard gout therapies.[1] 2. **Enroll in Amgen By Your Side**: Call **(877) 633-9521**, visit amgenbyyourside.com/krystexxa, or have your doctor submit.[2][3] Online form connects you to a Gout Nurse Advocate within 2 business days.[8] 3. **Assign a PAL**: Your dedicated Patient Access Liaison handles insurance checks, financial options, and logistics.[3][5][8] 4. **Benefits Investigation**: PAL summarizes your coverage—no medical advice, but educates on next steps.[3] 5. **Apply for Co-Pay/Assistance**: For commercial insurance, get $0 co-pay card.[2][7] Uninsured: PAL explores foundations.[2] 6. **Submit Forms**: Fax to 877-633-9522 or email GOUTABYS@amgen.com.[3] PAL coordinates prior authorizations if needed.[6] 7. **Start Infusions**: PAL helps find sites, schedule, and sends reminders.[3] Your PAL connects, coordinates, and champions you—plus access Peer Mentors (real patients) for support.[3][5] ## Timeline and Delivery - **Enrollment Contact**: Within 2 business days.[8] - **Benefits Summary**: Soon after enrollment.[3] - **Prior Auth/Assistance**: Varies; third-parties like AmeriPharma aim for 24-72 hours.[6] PAL streamlines. - **Infusions**: Every 2 weeks; PAL schedules at office/hospital/infusion center.[3] Delivery: Via infusion only, not pills—coordinated by PAL.[3] Expect reminders and check-ins.[3] ## Alternatives if Denied or Additional Help - **Independent Foundations**: Assistance Fund (Gout), HealthWell Gout Travel Fund (up to $2500/year).[7] - **Third-Party Services**: AmeriPharma for copay matching ($55M secured).[6] - **Peer Support**: Free patient mentors.[5] - **Doctor Discussion**: Explore other gout treatments or appeals. Re-enroll or call (877) 633-9521 for updates.[2] ## Disclaimer This guide is for informational purposes based on available program details as of latest data. Eligibility, terms, and availability can change—**always verify directly with Amgen By Your Side at (877) 633-9521**.[1][2] Not medical advice; consult your doctor. Amgen doesn't guarantee coverage. Program for US residents.[2][3] (Word count: 1028)

Program information last verified: March 30, 2026