Kloxxado
Generic: naloxone
Manufacturer: Emergent BioSolutions · Program:
Apply for AssistanceEligibility Criteria
Insurance Requirement
See program details
Residency
US residency required
Program Information
Processing Time
2–8 weeks
Delivery Method
Varies by program
Application Method
Online
Indicated For
opioid overdose
About This Medication
# Emergent BioSolutions Kloxxado Savings Card Patient Guide: How to Get Kloxxado at Low or No Cost Kloxxado (naloxone HCl) nasal spray 8 mg is a life-saving prescription medication used to reverse opioid overdoses, and Emergent BioSolutions offers a **Savings Card** that allows eligible patients to pay as little as $0 per box (up to 2 boxes per redemption) at participating pharmacies.[2][5][7] ## About Kloxxado **Kloxxado** is an opioid antagonist delivered as a higher-dose (8 mg) nasal spray for the emergency treatment of known or suspected opioid overdose in adults and children, addressing respiratory and central nervous system depression.[2][6][9] Unlike lower-dose options, its 8 mg dose is designed for situations where more naloxone may be needed, such as with potent opioids like fentanyl, though the clinical significance of the higher dose is still under study.[2][9] It's easy to use—no needles or special training required—and has a 3-year shelf life from manufacture.[2] **Important safety note**: Always call 911 immediately after administering Kloxxado, as its effects may wear off before the opioid does. Repeat doses every 2-3 minutes in alternating nostrils if needed until help arrives.[6] Kloxxado is available by prescription at retail pharmacies nationwide. If it's not in stock, pharmacies can order it within 1-2 days.[3] ## Who Qualifies for the Savings Card? The **Kloxxado Savings Card** is a manufacturer copay assistance program from Emergent BioSolutions, not a traditional patient assistance program (PAP) with strict income limits.[5][7] It's designed for quick access to reduce out-of-pocket costs. **Eligibility criteria**: - Must be 18 years or older. - Legal resident of the US or Puerto Rico. - Cannot be enrolled in government programs like **Medicare Part D, Medicaid, VA, TRICARE, FEHB, DOD, Medigap, or state pharmacy assistance programs**.[5] - Commercial insurance accepted (card used as secondary coverage); cash-paying patients also eligible.[5] - No other discounts can be combined.[5] This program prioritizes commercially insured or uninsured patients who need affordable access to naloxone for overdose reversal, especially those at risk: history of overdose/substance use disorder, high opioid doses (≥50 MME/day), or sleep apnea.[3][9] **No income thresholds** are specified, making it more accessible than many PAPs.[5] ## Income Eligibility Breakdown Unlike traditional PAPs, the Kloxxado Savings Card has **no income eligibility requirements**. Here's a comparison: | Category | Traditional PAPs (e.g., <400-500% FPL) | Kloxxado Savings Card | |-----------------------|-----------------------------------------|-----------------------| | **Income Limits** | Strict (e.g., 400% FPL for individual: ~$58,320) | **None** | | **Primary Focus** | Uninsured/low-income | Commercial/cash-pay | | **Gov't Insurance** | Often eligible | **Excluded** | | **Max Benefit** | Free meds for 1 year+ | $0 copay up to 2 boxes/redemption[5] | FPL = Federal Poverty Level (2026 guidelines vary by household; check HHS.gov for current). ## Insurance Requirements - **Commercial insurance**: Preferred. Pharmacists submit the card as secondary coverage using specific billing codes (RxBIN# 018844, PCN: 3F, Group: FCXXAD, Member ID: KLWB9137821). If rejected, retry with coverage code 03.[5] - **Medicare/Medicaid/TRICARE/VA/etc.**: **Not eligible** for the card. Kloxxado is covered by many plans, including most Medicaid—contact your insurer.[3] - **Uninsured**: Eligible; pay as little as $0 with card.[5] Kloxxado is widely covered, but the Savings Card bridges gaps for eligible patients.[3][5] ## Step-by-Step Application Process No formal application or income proof needed—the Savings Card acts as instant copay assistance.[5][7] 1. **Get a prescription**: Ask your doctor for Kloxxado 8 mg nasal spray if you're at overdose risk.[3][9] 2. **Download/print the Savings Card**: Available on kloxxado.com (search 'Savings Card').[5][7] 3. **Take to pharmacy**: Present prescription + card. Pharmacist processes via Change Healthcare (call 1-877-259-6893 for help).[5] 4. **Pay as little as $0**: Up to 2 boxes per use. Valid where permitted; not combinable.[5] **Pro tip**: Confirm state laws—some require prescriptions for naloxone.[3] ## Timeline and Delivery - **Access time**: Immediate at stocked pharmacies; 1-2 days if ordered.[3] - **Processing**: Pharmacy handles instantly with card—no pre-approval wait.[5] - **Delivery**: Pick up at pharmacy counter. No home delivery via this program.[3] Pharmacies keep it stocked as there's no generic equivalent.[3] ## Alternatives if Denied or Ineligible - **Insurance denied?** Appeal or use card if commercially eligible. Contact insurer.[3] - **Government insurance?** Check coverage—many Medicaid plans cover it. Explore state programs (e.g., free naloxone at pharmacies in some areas).[4] - **Community programs**: Harm reduction orgs distribute naloxone (ask for Kloxxado).[3] - **Other naloxone**: Narcan (4 mg), generics, or injectables like Zimhi. Some states offer free OTC/community access.[4][8] - **SAMHSA Helpline**: Free referral for treatment/resources: 1-800-662-HELP.[1] **No biosimilars** available—all are opioid antagonists.[6] ## Disclaimer This guide is for informational purposes based on publicly available data as of 2026.[2][5] Eligibility/terms may change—verify at kloxxado.com or with pharmacist. Savings Card void where prohibited/taxed. Not a substitute for medical advice. Always seek emergency care post-administration. Emergent BioSolutions not affiliated with this guide.
Program information last verified: March 30, 2026
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