Kanuma

Indicated For

Lysosomal Acid Lipase Deficiency (LAL-D)

About This Medication

# **Alexion OneSource CoPay Program** Patient Guide: How to Get **Kanuma (sebelipase alfa)** at Low or No Cost Kanuma (sebelipase alfa) is an enzyme replacement therapy used to treat lysosomal acid lipase (LAL) deficiency, a rare genetic condition that can lead to serious liver and heart problems if untreated. The **Alexion OneSource CoPay Program** from Alexion Pharmaceuticals helps eligible patients with **commercial insurance** reduce out-of-pocket costs for Kanuma, potentially to as little as $0, without income restrictions.[1][2][4][5][6] ## **Who Qualifies for the Program?** This program is designed for patients who need financial help with Kanuma costs. Key eligibility points include: - **Reside in the US or Puerto Rico** and be **18 years or older** (or have a financially responsible person who is).[4][6][8] - **Have commercial (private) insurance** covering Kanuma—not government programs like Medicare, Medicaid, or any federal/state-funded healthcare.[1][4][6] - **Valid prescription** for an FDA-approved use of Kanuma.[4] - **Enrollment in Alexion OneSource**, Alexion's free patient support program, which is required for co-pay assistance.[1][3][6][7] **Important:** No income check is required, making it accessible to a wide range of commercially insured patients. However, there may be an **annual maximum benefit** that varies by patient, after which you'll pay full out-of-pocket costs for the year.[4][6] ## **About Kanuma (Sebelipase Alfa)** Kanuma is a **biologic enzyme replacement therapy** infused intravenously, typically every two weeks, to replace the deficient LAL enzyme. It's approved for all ages with LAL deficiency, including rapidly progressive forms in infants. Treatment can improve liver function, reduce cholesterol buildup, and prevent life-threatening complications. Always follow your doctor's dosing instructions, as it's administered in a clinical setting.[3] **Why use the co-pay program?** Kanuma can be expensive, but this program covers eligible copays, coinsurance, and sometimes infusion costs, helping you focus on your health.[2][5][6] ## **Income Eligibility Breakdown** Great news: **Eligibility is not based on income**. There's no Federal Poverty Level (FPL) limit or household size requirements. As long as you meet the insurance and other criteria, you qualify.[1][4] For clarity, here's a table summarizing: | Household Size | Income Threshold | Eligible? | |---------------|------------------|-----------| | Individual | None | **Yes** (commercial insurance required) | | Couple | None | **Yes** (commercial insurance required) | | Family of 3 | None | **Yes** (commercial insurance required) | | Family of 4+ | None | **Yes** (commercial insurance required) | **Notes:** Program covers US residents only. Annual caps apply.[4][6] ## **Insurance Requirements** - **Must have commercial insurance** (e.g., employer-sponsored, marketplace plans) that covers Kanuma.[1][4][6] - **Not eligible** if on Medicare, Medicaid, VA, Tricare, or other government programs.[6] - Provide **front/back copies of insurance cards** with enrollment.[7] - The program **cannot be submitted to any third-party payer**—it's for out-of-pocket costs only.[6] ## **Step-by-Step Application Process** Applying is straightforward with **multiple options**. Expect personalized support from OneSource coordinators.[1][4] 1. **Discuss with your doctor**: Get a valid prescription for Kanuma.[4] 2. **Enroll in OneSource** (required for co-pay): - **Online**: Visit https://alexiononesource.com/kanuma/get-started, fill out the patient enrollment form, and submit.[1][4] - **Download form**: Get English (or other languages via phone), complete, **sign it** (allows health info sharing), and send.[1][3][7] - **Email**: OneSource@alexion.com[1][4][7] - **Fax**: 1-800-420-5150[1][4][7] 3. **Include required documents**: - Patient enrollment form (signed).[1][3][7] - Proof of commercial insurance (front/back cards).[7] - Prescription.[4] 4. **Call for help**: (888) 765-4747 (M-F, 8:30am-8pm ET). They offer interpreters.[1][4] 5. **OneSource reviews eligibility** and activates benefits.[4] **Tip**: Complete all red/required fields to avoid delays.[3][7] ## **Timeline and Delivery** - **Processing**: Not specified, but submit fully completed forms for fastest enrollment. OneSource starts support upon receipt.[1][3][7] - **Claims**: Submit within **365 days** of service date with proof of payment/EOB for reimbursement.[6] - **Delivery**: Co-pay card or reimbursement for out-of-pocket at pharmacy/infusion site. Medication via your pharmacy or specialty provider.[2][6] - Benefits renew yearly; track your annual max.[6] ## **Alternatives if Denied or Ineligible** - **If denied**: Appeal via OneSource (call 888-765-4747). Check if issue is insurance-related.[1] - **Government insurance**: Explore state programs or Alexion's patient assistance (separate from co-pay; may have income rules).[8] - **No biosimilars** available for Kanuma.[ ] - **Other options**: Independent foundations, state aid, or doctor for samples. Contact OneSource for guidance.[5] ## **Disclaimer** This guide is for informational purposes based on available program details as of 2026. Eligibility, terms, and benefits can change—always verify with Alexion OneSource at (888) 765-4747 or https://alexiononesource.com/kanuma. Not a substitute for medical/financial advice. Program not health insurance. Alexion reserves rights to modify/amend.[6] Word count: 962.

Program information last verified: March 30, 2026