Juxtapid

Indicated For

Homozygous Familial Hypercholesterolemia, HoFH

About This Medication

# Chiesi Juxtapid Patient Guide: How to Get Juxtapid at Low or No Cost Juxtapid (lomitapide) is a prescription medication used to treat **homozygous familial hypercholesterolemia (HoFH)** in adults, a rare genetic condition causing extremely high cholesterol levels. This guide explains the **Chiesi Total Care** support program, including the Copay Program and related assistance options from manufacturer Chiesi, to help eligible patients access Juxtapid at reduced or no cost.[1][2][4] ## About Juxtapid and HoFH **HoFH** is a serious inherited disorder where the body cannot remove LDL cholesterol (the 'bad' kind) effectively, leading to very high cholesterol levels and increased risk of heart disease.[2][9] Juxtapid works by inhibiting microsomal triglyceride transfer protein (MTP), reducing LDL cholesterol, total cholesterol, apolipoprotein B, and non-HDL cholesterol when used with a low-fat diet and other treatments like LDL apheresis.[2][9] **Important safety note**: Due to the risk of **hepatotoxicity** (liver damage), Juxtapid is only available through the **Juxtapid REMS Program**. Your doctor must be certified, and prescriptions are filled only by certified pharmacies. Patients need regular liver function tests.[4][5][6] Chiesi Total Care provides personalized support, including a Patient Education Liaison (PEL) for diet and education, a Nurse Case Manager for insurance navigation and refills, and help with financial assistance.[1][4] ## Who Qualifies for Assistance? Chiesi's programs target patients with commercial insurance facing high copays or coinsurance. Key eligibility: - **Diagnosis**: Confirmed clinical or lab diagnosis of HoFH in adults (18+).[2][4][9] - **Insurance**: Eligible for the Copay Program only if **not enrolled in government programs** like Medicare, Medicaid, Tricare, VA/DOD, or state assistance programs.[1] - **REMS Enrollment**: Doctor and pharmacy must be enrolled; patient authorizes support services.[4][5] Exact income thresholds for Chiesi's direct patient assistance are not publicly detailed; contact support for specifics. Independent programs like **Prescription Hope** offer broader access: - Individuals: Up to ~$50,000/year - Households: Up to $70,000/year (higher for larger families, up to $200,000).[7] These work alongside insurance and are not manufacturer-run.[7] ## Income Eligibility Breakdown Chiesi's Copay Program focuses on insurance status over strict income, but third-party options provide income-based help. Here's a comparison: | Household Size | Prescription Hope Max Income (Approx.) | Chiesi Copay Notes | |---------------|---------------------------------------|-------------------| | Individual | $50,000/year | Commercial insurance only; no government programs[1][7] | | Couple/HH2 | $70,000/year | Covers copay/coinsurance up to max; other requirements apply[1] | | Family of 3 | Increases toward $200,000 | N/A (call for details)[7] | | Family of 4+ | Up to $200,000/year | Excludes Medicare/Medicaid[1][7] | **Notes**: FPL % not specified. Always verify with (855) 898-2743. Guidelines can change.[1][7] ## Insurance Requirements - **Commercial Insurance**: Copay Program covers 100% of copay/coinsurance up to a maximum for eligible patients.[1] - **Government Insurance**: **Not eligible** for Copay Program (e.g., Medicare, Medicaid).[1][8] - **REMS Mandate**: All prescriptions require Juxtapid REMS Authorization Form, faxed to 1-855-898-2498.[4] - Nurse Case Manager helps verify benefits and prior authorizations.[1] If uninsured or underinsured, ask about independent financial assistance referrals.[1][3] ## Step-by-Step Application Process 1. **Confirm Diagnosis and REMS**: Ensure your doctor is REMS-certified (visit www.JUXTAPIDREMSProgram.com). Discuss if Juxtapid is right for you.[4][5] 2. **Get Prescribed**: Doctor completes and signs the Juxtapid REMS Authorization Form.[4] 3. **Enroll in Chiesi Total Care**: Doctor enrolls you for support services (insurance help, education, financial referrals). Authorize release of health info.[1][5] 4. **Contact Support**: Call **1-855-898-2743** (Mon-Fri, 8am-8pm ET) for Copay Program enrollment, copay card, or assistance referral. Nurse Case Manager coordinates.[1] 5. **Pharmacy**: Prescription goes to a certified REMS pharmacy. Support team handles prior auth and refills.[1][6] 6. **For Prescription Hope (alternative)**: Apply online or call; provide income proof, Rx, and insurance info. $60-70/month flat fee.[7] Your PEL will schedule in-person/phone sessions for diet and education.[1] ## Timeline and Delivery - **Initial Approval**: Varies by insurance; Nurse Case Manager helps expedite prior auth. Prescription Hope: 2-4 weeks after paperwork.[1][7] - **Delivery**: Direct from certified REMS pharmacies. Monthly refill coordination by Nurse Case Manager.[1][6] - **Ongoing**: Monthly check-ins for refills and monitoring.[1] Call support for exact timelines, as they depend on insurance.[1] ## Alternatives if Denied - **Appeal**: Work with Nurse Case Manager to appeal insurance denial.[1] - **Independent Programs**: Prescription Hope ($60/month, broad eligibility) or other copay/savings cards via sites like PrescriberPoint.[3][7] - **Other Treatments**: Discuss diet, LDL apheresis, or other lipid-lowering meds with your doctor.[2][9] - **Financial Aid Foundations**: Support refers to independent programs.[1] Chiesi may modify programs; check eligibility.[1] ## Disclaimer This guide is for informational purposes only and not medical or financial advice. Eligibility, terms, and availability can change. Consult your doctor and call (855) 898-2743 for personalized help. Juxtapid has serious risks; follow REMS requirements. Chiesi reserves rights to alter programs. Word count: 1028.

Program information last verified: March 30, 2026