Itovebi

Indicated For

Hormone receptor-positive, HER2-negative breast cancer with PIK3CA mutation

About This Medication

# Genentech Patient Foundation and Itovebi Access Solutions Patient Guide: How to Get Itovebi at Low or No Cost Itovebi (inavolisib) is a prescription medication developed by Genentech for treating certain types of advanced breast cancer, specifically PIK3CA-mutated, hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer in adults after prior endocrine therapy. This guide explains the **Genentech Patient Foundation and Itovebi Access Solutions** program, which offers **free Itovebi** for eligible patients based on income and insurance status, or co-pay help for those with coverage.[1][7] ## Who Qualifies for the Program? The program helps U.S. residents prescribed Itovebi by a licensed U.S. physician. Eligibility falls into groups based on insurance and finances: - **Uninsured patients**: Qualify if household income is under **$150,000** (adjusted for household size) and no coverage for Itovebi.[7][9] - **Insured patients**: Qualify if covered for Itovebi but out-of-pocket maximum exceeds **7.5% of yearly income**, or unable to afford cost-sharing.[7] - **Exclusions**: Not for government programs like Medicare, Medicaid, VA, or plans requiring AFP vendors, Maximizer/Accumulator programs.[5][7] **Note**: Exact FPL percentages aren't public; use the online eligibility tool or call (888) 941-3331.[4] ## About Itovebi (Inavolisib) **Itovebi** is a **PI3Kα inhibitor** tablet taken once daily with food, combined with palbociclib and fulvestrant. It targets genetic mutations driving cancer growth. Common side effects include high blood sugar (monitor levels), diarrhea, rash, mouth sores, and fatigue. Serious risks: severe hyperglycemia, lung issues, infections. Your doctor will guide dosing and monitoring. Always take as prescribed.[1] ## Income Eligibility Breakdown Specific thresholds vary by insurance status. Insured need income proof showing high OOP burden; uninsured have stricter limits. | Household Size | Uninsured Max Income (est. under $150k) | Insured (OOP >7.5% income) | |----------------|---------------------------------------|-----------------------------| | 1 | Under $150,000[7] | OOP >7.5% income[7] | | 2 | Adjusted under $150k* | OOP >7.5% income[7] | | 3 | Adjusted under $150k* | OOP >7.5% income[7] | | 4 | Adjusted under $150k* | OOP >7.5% income[7] | | 5+ | Call for details | OOP >7.5% income[7] | *Household size/income criteria apply; confirm via (888) 941-3331 or form.[7][8] No citizenship required.[7] ## Insurance Requirements - **Co-pay assistance** (Itovebi Access Solutions): Commercial or public insurance (not government-reimbursed).[program details] - **Free medicine** (Patient Foundation): Uninsured, or insured without Itovebi coverage/unable to afford costs. Invalid for federal/state programs (e.g., Medicare Part D).[7][program details] Check coverage first; Foundation helps if denied or unaffordable.[5] ## Step-by-Step Application Process Applications via **multiple methods**; both forms required: **Patient Consent Form** (you complete) and **Prescriber Foundation Form** (doctor completes).[1][7] 1. **Check eligibility**: Use online tool at gene.com/patients/patient-foundation/see-if-you-qualify or call (888) 941-3331 (M-F, 6am-5pm PT).[4][2] 2. **Complete Patient Consent Form**: Online (English/Spanish), sign/date. Include household size, DOB, ZIP.[1][7] 3. **Doctor completes Prescriber Form**: Page 2 details prescription, eligibility.[7] 4. **Submit together**: - **Online**: eSubmit or My Patient Solutions (doctor's portal).[1][3] - **Text photo**: 650-877-1111.[1] - **Fax**: 833-999-4363.[1][7] - **Phone help**: (888) 249-4918 or (888) 941-3331.[program details][2] 5. **Or apply via Itovebi site**: itovebi.com/financial-support/apply.html.[program details] **Tip**: Submit both forms at once for fastest processing.[1][7] ## Timeline and Delivery - **Processing**: 5 business days after receiving both forms. Office contacted with outcome/next steps.[1][9] - **Approval**: 1 year free medicine if eligible; no reenrollment if still qualify.[9] - **Delivery**: Shipped directly to patient (or pharmacy).[program details] - **Contact**: You'll hear from Foundation Specialist.[1] ## Alternatives if Denied - **Appeal insurance denial**: Apply to Foundation during appeal (no proof needed).[5] - **Other Genentech support**: Co-pay cards via Access Solutions for insured.[6] - **Local aid**: Foundation Specialists suggest area resources.[5] - **Independent foundations**: Search PAN Foundation, HealthWell. - **Doctor samples** or generic alternatives (none for Itovebi currently).[program details] ## Disclaimer This guide is for informational purposes, based on available program details as of 2026. Eligibility/rules change; confirm with Genentech at (888) 941-3331. Not medical/financial advice. Consult your doctor/insurer. Genentech not liable for errors. Program for U.S. only; exceptions possible.[1][7][9]

Program information last verified: March 30, 2026