← Find a medication
Autoimmune

Inflectra

Generic: infliximab-dyyb

Manufacturer: Pfizer  ·  Program: Pfizer enCompass Co-Pay Assistance Program

Apply for assistance

Free to apply. Service from $40/month, payable only when your application is ready to submit.

Eligibility Criteria

Insurance Requirement

Commercial prescription drug insurance coverage required; government beneficiaries not eligible

Residency

US resident

Income Threshold

Up to 300% FPL

Individual Income Limit

$43,740/year

Must be uninsured or publicly insured; commercial insurance ineligible

Program Information

Processing Time

2–4 weeks after complete application received

Delivery Method

shipped to patient

Application Method

Multiple

Reauthorization

Required, annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • Proof of insurance
  • Enrollment form

Indicated for

Crohn’s Disease, Ulcerative Colitis, Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Plaque Psoriasis

About This Medication

Pfizer enCompass Co-Pay Assistance Program Patient Guide: How to Get INFLECTRA at Low or No Cost

About INFLECTRA (Infliximab-dyyb)

INFLECTRA is a biosimilar medication used to treat inflammatory conditions including rheumatoid arthritis, Crohn's disease, ulcerative colitis, ankylosing spondylitis, psoriasis, and psoriatic arthritis. As a biosimilar, it works similarly to the original biologic drug but may be more affordable. The Pfizer enCompass Co-Pay Assistance Program helps eligible patients access INFLECTRA by reducing out-of-pocket costs through co-pay support and financial assistance.

Who Qualifies for This Program

To be eligible for the Pfizer enCompass Co-Pay Assistance Program, you must meet ALL of the following criteria:

  • Have commercial prescription drug insurance that covers INFLECTRA
  • NOT be enrolled in Medicare, Medicaid, or other state or federally funded health insurance programs
  • NOT be an active duty military member
  • NOT be a cash-paying patient (you must have insurance)
  • Be a U.S. resident

Important: There are no income limits for this program. Your eligibility is based solely on your insurance type, not your income level.

Insurance Requirements

This program is designed exclusively for patients with commercial insurance. The following insurance types are NOT eligible:

Insurance TypeEligible?
Commercial health insurance with prescription drug coverageYes
Medicare (including Medicare Advantage)No
MedicaidNo
TRICARE or VA benefitsNo
State-funded health programsNo
Self-pay/cash patientsNo

Your commercial insurance must cover INFLECTRA for your condition. If you're unsure whether your insurance qualifies, call Pfizer enCompass at 1-844-722-6672 (Monday-Friday, 8 AM-8 PM ET) to verify.

How to Apply

There are multiple ways to enroll in the Pfizer enCompass Co-Pay Assistance Program:

Option 1: Online Self-Enrollment (Fastest)

Visit www.PfizerCopay.com and complete the enrollment form directly. Your co-pay card will be activated in real time during enrollment. This option works best if you don't need additional support like benefit verification or prior authorization assistance.

Option 2: Provider Portal

Your healthcare provider can enroll you through the provider portal at www.pfizerencompassonline.com. Your provider will complete the enrollment form and submit it to Pfizer enCompass.

Option 3: Phone Enrollment

Call 1-844-722-6672 (Monday-Friday, 8 AM-8 PM ET) to speak with a Pfizer enCompass Access Counselor who can help you enroll and answer questions about the program.

Option 4: Mail or Fax

Your healthcare provider can mail or fax the completed enrollment form to:

  • Pfizer enCompass Co-Pay Assistance Program
  • P.O. Box 220040
  • Charlotte, NC 28222
  • Fax: 1-877-847-3291

Required Documents

When applying, you'll need to provide:

  • Proof of commercial insurance (insurance card or policy information)
  • Completed enrollment form (available online or by mail)
  • Patient demographic information (name, date of birth, contact information)
  • Prescription information (medication name, prescribing provider)

If you're applying through your healthcare provider, they may help gather some of this information.

What Happens After You Apply

Approval and Co-Pay Card

Once approved, you'll receive an approval letter containing your co-pay card numbers. If you enrolled online, your card is activated immediately. Your healthcare provider will also receive notification of your approval.

Co-Pay Support

The program will help reduce your out-of-pocket costs for INFLECTRA. The exact amount of assistance depends on your specific insurance plan and co-pay amount.

Additional Support Available

If you need help with:

  • Prior authorization from your insurance company
  • Benefit verification to understand your coverage
  • Insurance appeals if your claim is denied
  • Device and starter kits (where appropriate)

Pfizer enCompass can provide this support at no additional cost.

Submitting Co-Pay Claims

After you receive INFLECTRA, you can submit co-pay claims to get reimbursed for your out-of-pocket costs:

Timeline for Submission

Submit your claim within 180 days of the date of service shown on your Explanation of Benefits (EOB).

How to Submit

Online (Recommended): Visit www.PfizerCopay.com and submit your claim through the portal.

By Fax: Fax your completed claim form along with your EOB to 1-877-847-3291.

What to Include

  • Completed Pfizer Co-Pay Claim Form (or CMS-1500 or UB-04 form)
  • Copy of your Explanation of Benefits (EOB) or dated pharmacy receipt
  • Your patient group number and member ID (from your approval letter)
  • Your out-of-pocket amount paid for INFLECTRA

Claim Approval

Once your claim is approved, you'll receive a confirmation email notifying you that payment will be sent.

Timeline and Delivery

  • Enrollment: Immediate (if applying online) to several business days (if mailing/faxing)
  • Co-pay card activation: Real-time upon online enrollment
  • Claim processing: Varies; you'll receive email confirmation when approved
  • Reimbursement delivery: Sent after claim approval (method depends on your submission)

Program Terms and Renewal

This program's terms and offers expire at the end of each calendar year. You'll need to reauthorize your enrollment annually to continue receiving co-pay assistance in the following year. Pfizer enCompass will contact you about renewal before your current enrollment expires.

What If Your Application Is Denied?

If you're denied enrollment, possible reasons include:

  • You don't have commercial insurance
  • Your insurance is government-funded (Medicare, Medicaid, etc.)
  • You're a cash-paying patient
  • Your insurance doesn't cover INFLECTRA

Next steps:

  1. Call Pfizer enCompass at 1-844-722-6672 to understand why you were denied
  2. Ask if you qualify for other Pfizer patient assistance programs
  3. Explore alternative biosimilars like Remicade (infliximab), which may have different assistance programs
  4. Contact your healthcare provider to discuss other treatment options or insurance alternatives

Alternative Medications

If you don't qualify for this program or need additional options, ask your healthcare provider about:

  • Remicade (infliximab) - The original biologic that INFLECTRA is based on; may have its own assistance programs
  • Other TNF inhibitors or biologic medications for your condition

Important Disclaimer

This guide provides general information about the Pfizer enCompass Co-Pay Assistance Program as of March 2026. Program eligibility, benefits, and terms may change. For the most current and complete information, visit www.PfizerCopay.com or call 1-844-722-6672. Always consult with your healthcare provider and insurance company about your specific coverage and eligibility. This program is not insurance and does not replace your health insurance coverage.

Contact Information

Pfizer enCompass Co-Pay Assistance Program

  • Phone: 1-844-722-6672 (Monday-Friday, 8 AM-8 PM ET)
  • Website: www.PfizerCopay.com
  • Mailing Address: P.O. Box 220040, Charlotte, NC 28222
  • Fax: 1-877-847-3291

Program information last verified: March 30, 2026

Ready to apply for Inflectra assistance?

ProvisionRX manages the complete application process. Start your application in about 15 minutes.

Start My ApplicationBrowse All Medications

Need help finding a program?