IDHIFA

Indicated For

Relapsed or refractory acute myeloid leukemia (AML) with IDH2 mutation

About This Medication

# Bristol Myers Squibb Patient Assistance Foundation (BMSPAF) Patient Guide: How to Get IDHIFA (enasidenib) at Low or No Cost IDHIFA (enasidenib) is a prescription medication used to treat adults with relapsed or refractory acute myeloid leukemia (AML) with an isocitrate dehydrogenase-2 (IDH2) mutation, as confirmed by an FDA-approved test. The **Bristol Myers Squibb Patient Assistance Foundation (BMSPAF)** offers this drug at no cost to eligible patients who meet income and insurance criteria, providing a 90-day supply shipped directly to your home or doctor's office.[1][2][4][5] ## About IDHIFA (enasidenib) **IDHIFA** targets a specific genetic mutation in AML cancer cells. It works by blocking the IDH2 enzyme, which helps cancer cells grow, leading to their death and promoting normal blood cell production. Common side effects include nausea, vomiting, diarrhea, and differentiation syndrome (a serious condition requiring prompt medical attention). Always consult your doctor for personalized advice on usage, monitoring, and risks. This program helps make treatment accessible when costs are a barrier.[1] ## Who Qualifies for BMSPAF? BMSPAF is designed for U.S. residents (including Puerto Rico) aged 18+ facing financial hardship. Key eligibility factors include: - **Low household income** below the Foundation's guidelines (specific Federal Poverty Level percentages not publicly detailed; proof required).[1][2] - **Limited or no prescription coverage**, or high out-of-pocket costs (e.g., Medicare Part D patients who spent at least 3% of annual income on prescriptions).[1] - Uninsured, underinsured, Medicare, Medicaid, or commercially insured patients may qualify if they can't afford copays.[1][5] Meeting these doesn't guarantee approval, as BMSPAF reviews cases individually and may audit finances.[1][4] ## Income Eligibility Breakdown Exact income thresholds aren't specified in program materials, but eligibility ties to household income limits with required proof. Provide documents like federal tax returns (1040), W-2s, 1099s, pay stubs, Social Security statements, or pension info. For non-filers, use IRS Form 4506-T.[1][2] Here's a general guide based on typical patient assistance programs (consult BMSPAF for your situation): | Household Size | Estimated Max Annual Income (e.g., ~400-500% FPL)* | |----------------|---------------------------------------------------| | 1 (Individual) | $60,000 - $75,000 | | 2 (Couple) | $80,000 - $100,000 | | 3 | $100,000 - $125,000 | | 4 | $120,000 - $150,000 | | 5+ | Add ~$20,000 - $25,000 per additional member | *These are illustrative; actual limits vary and require verification. Medicare Part D adds a 3% income spend threshold for out-of-pocket costs.[1] Always call 1-800-736-0003 for current guidelines.[3][6] ## Insurance Requirements - **Uninsured**: Fully eligible if income-qualified.[1] - **Underinsured/Commercially Insured**: Qualify if unable to afford copays.[1][5] - **Medicare Part D**: Eligible if you've spent ≥3% of household income on prescriptions (pharmacy printout required).[1] - **Medicaid/Medicare A/B/VA**: May qualify if no/low coverage for IDHIFA or high costs.[1] List all insurances on the form. BMSPAF coordinates with providers but can't override coverage.[1][4] ## Step-by-Step Application Process 1. **Gather Documents**: Proof of income (tax return, pay stubs, etc.), residency (utility bill/ID), current prescription for IDHIFA, provider notes.[1][2] 2. **Download Form**: Visit BMSPAF.org or call 1-800-736-0003 / 1-800-861-0048.[1][3][6] 3. **Complete Sections**: - **Patient (Section I)**: Name, SSN (optional), address, DOB, income, household size, insurance, meds list, sign consent.[1] - **Provider (Sections II/III)**: Treatment details, prescription (attach separately), shipping info, sign certification.[1][2] 4. **Submit**: Mail to PO Box 220769, Charlotte, NC 28222-0769 or P.O. Box 1058, Somerville, NJ 08876; Fax: 1-800-736-1611 or 888-776-2370. No email.[1][2][3][4] 5. **Track**: Note case # if assigned. Incomplete apps delay processing.[1] Applications are free; no charge to apply.[1] ## Timeline and Delivery Processing time isn't specified but expect review upon receipt, with mail notification of decision. Approved patients get a **90-day supply** shipped to home/PO Box or provider's office.[2][4][5] Enrollment lasts up to 1 year; **reauthorization required annually** (or January for Medicare).[3][5] Refills need new full application with updated proof.[2][4] ## Alternatives if Denied or Ineligible - **Appeal**: Contact BMSPAF for reasons and resubmit corrected docs.[1] - **Other BMS Programs**: BMS Access Support for copay help (bmsaccesssupport.com).[7][8] - **General Resources**: RxHope.com, NeedyMeds.org, or state programs.[2][4] - **No biosimilars** for IDHIFA listed.[provided] - Doctor may explore generics, trials, or 340B clinics. ## Disclaimer This guide is for informational purposes based on available sources as of 2026. Program rules change; verify with BMSPAF at 1-800-736-0003 or bmspaf.org. Not medical/financial advice—consult professionals. Approval not guaranteed; false info may disqualify. BMS not liable for errors.[1][3][6]

Program information last verified: March 25, 2026