Hepzato Kit

Indicated For

uveal melanoma with unresectable hepatic metastases

About This Medication

# HEPZATO KIT Access 360 Patient Guide: How to Get Hepzato Kit at Low or No Cost HEPZATO KIT Access 360 is a copay assistance program from Delcath Systems, Inc., that helps eligible commercially insured patients in the US get **Hepzato Kit (melphalan)** for as little as $0 out-of-pocket, up to a $10,000 annual benefit.[1][3] This guide explains eligibility, the drug, application steps, and more to make your treatment journey smoother.[1][2] ## About Hepzato Kit **Hepzato Kit** is an FDA-approved liver-directed treatment for adults with **uveal melanoma** (a rare eye cancer) that has spread to the liver in ways that cannot be surgically removed.[3][4][5] It targets **unresectable hepatic metastases** affecting less than 50% of the liver, with no or limited spread to other areas like bone, lymph nodes, skin, or lungs (where those can be treated surgically or with radiation).[3][8] The kit uses a **unique 3-step system** during a procedure called **Percutaneous Hepatic Perfusion (PHP)**. Small catheters temporarily isolate the liver's blood supply from the rest of your body. High-dose **melphalan** (a chemotherapy drug) is then delivered directly to liver tumors over 30 minutes, followed by a washout period. An extracorporeal filter captures the drug-laden blood to minimize side effects elsewhere in the body.[3][7][9] Treatments occur every 6-8 weeks, up to 6 times, based on recovery and doctor judgment.[8] **Important safety note**: Hepzato Kit is only available through the **HEPZATO KIT REMS** program due to risks like hemorrhage, liver injury, clots, and myelosuppression (low blood counts).[2][5][6] It must be given at **REMS-certified facilities** by trained teams.[1][2] ## Who Qualifies for HEPZATO KIT Access 360? This is a **copay assistance program**, not free drug for uninsured patients. You may qualify if you meet **all** these criteria:[1] - Have **commercial insurance** (not Medicare, Medicaid, or government insurance).[1] - Live in the **US** and receive treatment at a **Delcath REMS-certified facility** (use their Healthcare Setting Locator).[1] - Are prescribed **Hepzato Kit** for eligible uveal melanoma as described above.[3] No specific **income thresholds** are required, making it accessible for many insured patients regardless of earnings.[1] It's not insurance and can change or end anytime.[1] ## Income Eligibility Breakdown HEPZATO KIT Access 360 does **not use income limits** like many programs tied to Federal Poverty Levels (FPL). Instead, eligibility focuses on insurance type and treatment location. Here's a simple table: | Eligibility Factor | Requirement | Details | |--------------------|-------------|---------| | **Insurance** | Commercial only | Excludes Medicare, Medicaid, VA, Tricare, etc.[1] | | **Residency** | US resident | Treated in US at certified site.[1] | | **Income** | None | No FPL or household size limits.[1] | | **Medical** | Doctor prescribed | For eligible uveal melanoma; REMS facility required.[1][3] | | **Benefit** | Up to $10,000/year | Covers copays for as low as $0.[1] | This broad approach helps more patients focus on health, not costs.[1] ## Insurance Requirements **Commercial insurance is required**—the program covers your copays, coinsurance, or deductibles for Hepzato Kit.[1] It does **not** work with: - Medicare Part D or Medicare Advantage. - Medicaid. - Uninsured or underinsured patients. If you have commercial coverage but high out-of-pocket costs, this program can reduce them significantly.[1] Confirm your plan qualifies via the program's navigator.[3] ## Step-by-Step Application Process 1. **Talk to your doctor**: Ensure Hepzato Kit is right for you and your facility is REMS-certified.[1][2] 2. **Visit hepzatokitaccess.com**: Click **Enroll Now** to start.[1] 3. **Complete the form**: Provide your info, insurance details, and prescription.[1] 4. **Get personalized help**: A **clinical navigator** guides you, answers questions, and handles paperwork.[1][3] 5. **Approval**: If eligible, use your benefit card at pharmacy or infusion for copay help.[1] The process is patient-friendly with support every step.[1] ## Timeline and Delivery - **Processing**: Quick enrollment; navigators assist promptly.[1] - **Approval**: Often same-day or within days, but varies.[1] - **Delivery**: Hepzato Kit is administered **only at REMS-certified facilities** via PHP procedure—not shipped home.[2][7] Your team handles infusion every 6-8 weeks.[8] - **Refills**: Benefit renews per calendar year (up to $10,000); reauthorization may apply per treatment cycle.[1] ## Alternatives if Denied or Ineligible - **Switch insurance**: If Medicare, explore Extra Help or state programs (not covered here).[1] - **Manufacturer exceptions**: Contact navigator for case-by-case review.[1] - **Financial aid**: General cancer funds like CancerCare or Patient Access Network (check eligibility separately). - **Clinical trials**: Search ClinicalTrials.gov for uveal melanoma studies. - **Other therapies**: Best alternative care (BAC) like immunotherapy; discuss with oncologist.[6][8] - **No biosimilars**: Hepzato Kit is unique; no direct alternatives listed.[ ] ## Disclaimer This guide is for informational purposes based on available program details as of latest updates. Eligibility, benefits, and terms can change; always verify at hepzatokitaccess.com or with Delcath.[1] Not insurance. Consult your doctor for medical advice. Delcath not liable for decisions based on this guide. Word count: 952.

Program information last verified: March 30, 2026