HepaGam B

Indicated For

Hepatitis B virus (HBV) prevention post-liver transplant, post-exposure prophylaxis

About This Medication

# Saol Therapeutics HepaGam B Patient Guide: How to Get HepaGam B at Low or No Cost HepaGam B (Hepatitis B Immune Globulin Intravenous (Human)) is a specialized medication from **Saol Therapeutics** used to prevent Hepatitis B recurrence after liver transplantation or for post-exposure prophylaxis in high-risk situations. Unfortunately, no dedicated patient assistance program (PAP) for free or low-cost HepaGam B was identified from available sources, but patients can explore general hepatitis resources, insurance options, and contact the manufacturer directly for support.[1][2][4] ## About HepaGam B **HepaGam B** is an FDA-approved immune globulin derived from human plasma, containing high levels of antibodies against the Hepatitis B virus (HBV). It is administered intravenously (IV) or intramuscularly (IM) and serves two main purposes:[3][7] - **Prevention of HBV recurrence** in HBsAg-positive patients following liver transplantation. Dosing starts high post-transplant (e.g., 10,000 International Units) and adjusts based on anti-HBs antibody levels (>500 IU/L target).[3][5] - **Post-exposure prophylaxis** for acute exposure to HBsAg-positive blood, perinatal exposure in infants of HBsAg-positive mothers, sexual exposure, or household contact with acute HBV infection.[3][5] Common side effects are rare but include hypotension and nausea (2% of trial patients). Report issues to Saol at 1-833-644-4216 or FDA at 1-800-FDA-1088.[3] Always use under medical supervision due to potential infection risks from plasma sourcing.[3] ## Who Qualifies for Assistance? No specific **Saol Therapeutics PAP** exists for HepaGam B based on current data. Searches across databases like RxAssist and manufacturer sites show no income-based free medication program.[4][6] However, eligibility for help may come from: - **General hepatitis B programs** covering immune globulins or related meds (e.g., Patient Advocate Foundation for insured patients under 400% FPL).[2] - **Insurance coverage** (Medicare Part B often covers injectables like HepaGam B; check prior authorization).[5] - **Manufacturer inquiry**: Contact Saol directly, as they manage expanded access for other products and may offer case-by-case support.[1] ## Income Eligibility Breakdown Without a formal PAP, there are **no set income thresholds** for HepaGam B. For reference, general hepatitis programs use these Federal Poverty Level (FPL) guidelines (2026 estimates; verify current HHS figures): | Household Size | 400% FPL (e.g., Co-Pay Programs) | Notes | |---|---|---| | Individual | ~$60,000 | Common cap for nonprofit aid.[2] | | Couple | ~$81,000 | Adjusts annually. | | Family of 3 | ~$102,000 | Patient Advocate Foundation example.[2] | | Family of 4 | ~$123,000 | Covers insured/underinsured. | **No Saol-specific limits found.** Uninsured patients may qualify for broader aid via Prescription Hope (~$50/month for some HBV meds).[2] ## Insurance Requirements HepaGam B (J-code J1573) is typically covered by **Medicare Part B** (injectables), Medicaid (with criteria like transplant documentation), and commercial plans.[4][5] Requirements include:[5] - Proof of HBsAg-positive status and transplant or exposure. - Prior authorization for continuation (e.g., 12 months for transplant prevention). - Monitoring anti-HBs levels. **No PAP insurance exclusions noted**, but uninsured patients lack direct manufacturer free drug access.[4] Contact your plan or use copay cards from nonprofits.[2] ## Step-by-Step Application Process 1. **Consult your doctor**: Discuss HepaGam B need; they handle requests (patients cannot apply alone).[1] 2. **Check insurance**: Submit prior auth with transplant/exposure proof.[5] 3. **Contact Saol Therapeutics**: Call 1-833-644-4216 for adverse events or potential unreported aid; ask about compassionate use.[3][1] 4. **Explore general programs**: - Patient Advocate Foundation (Copays.org): For insured <400% FPL.[2] - Prescription Hope: 877-296-4673 for $50/month options.[2] - RxAssist.org: Search broader databases.[6] 5. **Provider coordination**: Use specialty pharmacies like ASD Healthcare (800-746-6273).[8] ## Timeline and Delivery **No PAP processing time** specified, as none exists. Insurance prior auth: 1-2 weeks typically. Expanded access analogs aim for 7-day response.[1] Delivery via specialty pharmacy (IV/IM administration in clinic/hospital).[4][8] Track anti-HBs levels weekly post-transplant.[3] ## Alternatives if Denied - **Switch programs**: Gilead Support Path (for antivirals, not IG), or mail-order discounts.[2] - **Biosimilars**: None listed for HepaGam B.[program data] - **Discount cards**: GoodRx or similar for partial savings (check J1573 pricing).[4] - **Appeal insurance**: Provide more docs (e.g., test results).[5] - **Clinical trials**: Check ClinicalTrials.gov for HBV studies.[1] ## Disclaimer This guide is for informational purposes only and not medical/financial advice. No guaranteed assistance program exists for HepaGam B; details based on 2026 data and may change. Consult healthcare providers, verify eligibility, and contact Saol at 1-833-644-4216. Risks include infection from plasma products. Always follow prescribing info.[3][4]

Program information last verified: March 30, 2026