Granix

GRANIX Patient Guide: How to Get Granix (tbo-filgrastim) at Low or No Cost

Granix (tbo-filgrastim) is a prescription injection used to reduce the duration of severe neutropenia in patients receiving chemotherapy for non-myeloid cancers, helping to shorten the time neutrophils (key white blood cells that fight infection) are dangerously low.[2][10] This guide explains Teva Pharmaceuticals' GRANIX Patient Savings Program, a copay assistance option primarily for commercially insured patients facing high out-of-pocket costs, along with other pathways for broader access.[1][4]

About Granix (tbo-filgrastim)

Granix is a granulocyte colony-stimulating factor (G-CSF) that stimulates bone marrow to produce more neutrophils after chemotherapy damages it.[2][10] It's FDA-approved for adults and children 1 month and older with non-myeloid malignancies (cancers not originating in bone marrow, like breast, lung, or ovarian cancer) undergoing myelosuppressive chemotherapy.

• How it's given: Subcutaneous injection, typically daily for a few days starting 24 hours after chemotherapy, until neutrophil counts recover. Dosage aims to keep absolute neutrophil count (ANC) from exceeding 10,000/mm³.[1][10]
• Why it's important: Chemotherapy often causes neutropenia, increasing infection risk. Granix can shorten severe neutropenia by about 1 day, potentially reducing hospitalization needs.[10]

Key safety notes (discuss with your doctor):

• Contraindicated if allergic to filgrastim or pegfilgrastim.[1][2]
• Rare but serious risks: splenic rupture (watch for upper abdominal/shoulder pain), sickle cell crises, aortitis, ARDS, or alveolar hemorrhage.[1][10]
• Monitor blood counts twice weekly; effects reverse quickly upon stopping.[1]

Granix is often administered in a doctor's office or hospital (medical benefit), not always retail pharmacy.[8]

Who Qualifies for Assistance?

Teva's GRANIX Patient Savings Program targets commercially insured patients (private insurance, not government plans like Medicare/Medicaid) with a valid Granix prescription.[1][4] It reduces copays but has limitations (e.g., no substitutions allowed).[4]

• Primary eligibility: Commercial insurance covering Granix; high copays or deductibles.[1][4]
• Not for: Uninsured, Medicare/Medicaid, or government-insured patients.[4][7]
• Income-based programs: No specific Teva PAP with FPL thresholds listed; third-party options like Prescription Hope offer Granix for $70/month after pre-qualification (income/insurance reviewed).[6] Independent foundations (e.g., PAN Foundation, HealthWell) may help Medicare patients.[7][9]

Income Eligibility Breakdown

Teva's program lacks public income caps, focusing on insurance type.[4] For broader PAPs, eligibility often ties to 400% Federal Poverty Level (FPL) or less. Here's a general table (2026 estimates; verify current FPL):

Table illustrative; Teva program income-agnostic for commercial patients. Always check program sites.[1][4][6]

Insurance Requirements

• Commercial insurance required for Teva Savings Card; fills at pharmacy with card.[1][4]
• Medicare/Medicaid: Ineligible for Teva program. Use independent copay foundations (e.g., Patient Access Network, HealthWell) or PAPs like Prescription Hope ($70/month).[6][7][9]
• No/low insurance: Third-party services or competitor-inspired safety nets (e.g., Amgen model for Neupogen).[7]
• Granix often medical benefit (in-office), so copays vary by plan.[8][9]

Step-by-Step Application

1. Get prescribed: Confirm Granix suitability with oncologist.[2][10]
2. Check eligibility: Commercial? Download/print GRANIX Savings Card from granixrx.com/resources or granixhcp.com.[1][2][4]
3. Fill prescription: Take card to pharmacy. Pharmacist reviews terms.[4]
4. For non-commercial: Enroll in Prescription Hope (prescriptionhope.com; pre-qualify online/phone) or call foundations (e.g., 1-888-4ASSIST for Amgen Assist referrals).[6][7]
5. Submit if needed: No formal app for Teva card; instant at pharmacy. Others may require forms/docs.[5][6]

Timeline and Delivery

• Teva Savings: Immediate copay reduction at pharmacy fill.[1][4]
• Third-party PAPs: Processing 1-4 weeks; delivery via mail or pharmacy.[5][6]
• Refills: Use card each fill; reauthorization per treatment cycle (monitor ANC).[1][10]
• Expect 1-2 day neutrophil drop if stopped; resume as prescribed.[1]

Alternatives if Denied

• Switch biosimilars: Zarxio (filgrastim-sndz), Nivestym, Releuko (some no PA).[8]
• Foundations: PAN, HealthWell, Patient Advocate.[7][9]
• Other PAPs: RxAssist.org lists forms; Prescription Hope ($70/mo).[5][6]
• Competitor programs: Neupogen Safety Net (no-cost for qualifying uninsured).[7]
• GoodRx/copay cards: Check for Granix discounts.[9]

Disclaimer

This guide synthesizes public info as of 2026; programs change. Not medical/financial advice. Consult doctor, pharmacist, or program directly (e.g., granixrx.com).[1][2][4] Teva not affiliated. Verify eligibility/terms. Risks exist; report side effects to FDA 1-800-FDA-1088.