Gamifant

Indicated For

Primary hemophagocytic lymphohistiocytosis (HLH), Macrophage activation syndrome (MAS)

About This Medication

# Gamifant Cares Patient Guide: How to Get Gamifant (emapalumab-lzsg) at Low or No Cost Gamifant Cares, offered by Sobi, Inc., is a comprehensive patient support program that helps eligible patients access **Gamifant (emapalumab-lzsg)**, a prescription medication used to treat primary hemophagocytic lymphohistiocytosis (HLH) in adults and children, including newborns. This guide explains eligibility, application steps, and support options in simple terms to empower you or your loved one on this treatment journey. ## About Gamifant (emapalumab-lzsg) **Gamifant** is an intravenous medication that neutralizes interferon gamma (IFN-γ), a protein driving the dangerous hyperinflammation in primary HLH—a rare, life-threatening immune disorder where the body attacks its own cells, leading to organ damage, fever, and infections. Approved by the FDA, it's given in a hospital or clinic setting under medical supervision, typically twice weekly after an initial test dose. Common side effects include infections, high blood pressure, and fever; always discuss risks with your doctor. Gamifant can reduce the need for high-dose steroids, offering hope for better disease control. The Gamifant Cares program goes beyond medication access. It connects you with dedicated Care Managers, nurse educators, and financial help to navigate insurance, treatment education, and costs. Whether you have commercial insurance, are underinsured, or uninsured, the program tailors support to your needs. ## Who Qualifies for Gamifant Cares? Gamifant Cares offers two main tracks: **Copay Assistance** for those with commercial insurance and **Patient Assistance** for uninsured or non-covered patients. Qualification is determined on a **case-by-case basis**—there's no fixed income threshold like a percentage of the Federal Poverty Level (FPL). Factors include financial need, insurance status, U.S. residency (including Puerto Rico), and a valid prescription for Gamifant. - **Copay Assistance**: For commercially insured patients facing high out-of-pocket costs. - **Patient Assistance**: For uninsured patients or those without Gamifant coverage; provides free medication if eligible. Contact Gamifant Cares at **(833) 597-6530** (Monday-Friday, 8:30 AM–7:00 PM ET) for a personalized eligibility review. A Care Manager will guide you. ## Income Eligibility Breakdown Unlike many programs with strict cutoffs, Gamifant Cares evaluates finances individually. No public household size limits (e.g., individual, couple, family of 3 or 4) or FPL percentage are specified—eligibility hinges on demonstrated need via income proof. | Household Type | Income Threshold | Notes | |---------------|------------------|-------| | Individual | Case-by-case | Submit recent tax returns, pay stubs, or W-2s for review. | | Couple | Case-by-case | Program prioritizes financial hardship. | | Family of 3 | Case-by-case | Larger families may qualify with higher but proportionate income. | | Family of 4+ | Case-by-case | Contact for details; no upper FPL limit published. | **Tip**: Even if your income is above typical program limits, apply—exceptions occur for high medical costs or rare disease burdens. ## Insurance Requirements The program is flexible: - **Commercial Insurance**: Required for copay help; covers deductibles, copays, or coinsurance up to program limits. - **Any Coverage**: Works with Medicare, Medicaid, or other plans for benefit investigations and appeals. - **Uninsured/Non-Covered**: Qualify for free drug via Patient Assistance. Gamifant Cares performs a **benefits investigation** upon enrollment, summarizing your coverage and out-of-pocket estimates. They assist with prior authorizations or appeals if needed. ## Step-by-Step Application Process Applying is straightforward—start by phone, as there's no online form listed. 1. **Get a Prescription**: Ask your healthcare provider (HCP) for Gamifant. They complete the Prescription and Enrollment Form. 2. **Call Gamifant Cares**: Dial **(833) 597-6530**. Provide your details; a Care Manager assigns support. 3. **Submit Documents**: Fax (1-866-895-7204) or email (GamifantCares@pharmacord.com) the form with: - Prescription. - Insurance cards/info. - Income docs (tax returns, pay stubs). 4. **Eligibility Review**: Care Manager assesses finances and insurance. 5. **Approval & Start**: If approved, medication ships; copay card issued if applicable. Your HCP and you sign the form. Enroll in the optional Nursing Support Program for HLH education from Sobi nurses. ## Timeline and Delivery - **Processing**: Typically **2-4 weeks** from submission, including benefits check and eligibility. - **Delivery**: Medication **shipped directly to you** or your provider; specialty pharmacy handles refills. - **Reauthorization**: Required for ongoing treatment—your doctor resubmits proof of need periodically. Track status by calling your Care Manager. ## Alternatives if Denied If ineligible: - Appeal with more financial docs. - Explore Sobi's other supports or general HLH resources. - Check independent programs like RxAssist or PAN Foundation. - Discuss generics/biosimilars (none currently) or clinical trials with your doctor. - State assistance or hospital charity care may help. Gamifant Cares can suggest options. ## Important Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility, benefits, and terms can change; contact Gamifant Cares for current details. Always consult your healthcare provider. Sobi, Inc. reserves rights to modify/discontinue the program. Medication risks exist—review full Prescribing Information and Patient Medication Guide.

Program information last verified: March 30, 2026