EYLEA

Indicated For

Age-related macular degeneration (AMD), diabetic macular edema, retinal vein occlusion

About This Medication

# EYLEA4U Patient Assistance Program Patient Guide: How to Get EYLEA (aflibercept) at Low or No Cost EYLEA (aflibercept) is an injectable medication used to treat serious eye conditions like wet age-related macular degeneration (AMD), diabetic macular edema (DME), and retinal vein occlusion (RVO) by blocking abnormal blood vessel growth in the eye. The **EYLEA4U Patient Assistance Program** from **Regeneron Pharmaceuticals** helps eligible **uninsured or underinsured patients** get EYLEA at low or no cost if you meet income guidelines based on the federal poverty level (FPL). ## Who Qualifies for EYLEA4U? This program is for patients facing financial hardship due to lack of insurance or inadequate coverage. Key qualifications include: - Being **uninsured** (no prescription insurance) or **underinsured** (insurance doesn't cover enough of the cost). - **Household income** at or below a certain percentage of the **Federal Poverty Level (FPL)**. Exact percentages aren't publicly detailed, but programs like this often use 400-500% FPL—call (855) 395-3248 to confirm your eligibility. - **U.S. resident** (program serves U.S. patients only). - **Valid prescription** from a licensed physician for EYLEA. **Important note**: Patients with **Medicare Part D** are **not eligible**. If you have Medicare, explore other options like Extra Help or manufacturer copay cards through EYLEA4U's reimbursement support. ## About EYLEA (aflibercept) **EYLEA** is a prescription eye injection given every 4-8 weeks by an ophthalmologist in a clinic. It works by inhibiting vascular endothelial growth factor (VEGF), reducing swelling and vision loss from leaking blood vessels. Common side effects include eye pain, floaters, or increased eye pressure—discuss risks with your doctor. Treatment is ongoing, so assistance programs help manage repeat costs, which can exceed $10,000 per year without support. ## Income Eligibility Breakdown Eligibility hinges on **household income** compared to the **2026 Federal Poverty Level (FPL)**. While exact FPL percentages aren't specified, here's a general table based on typical patient assistance thresholds (confirm with program via phone): | Household Size | Estimated Max Income (400% FPL example) | Notes | |---------------|-----------------------------------------|-------| | 1 person | ~$60,000/year | Adjusts annually; includes all income sources. | | 2 people | ~$81,000/year | Household = you + spouse/dependents. | | 3 people | ~$102,000/year | Proof like tax returns required. | | 4 people | ~$123,000/year | Add ~$21,000 per additional person. | *Table is illustrative—**call (855) 395-3248** for your exact threshold.* ## Insurance Requirements - **Uninsured**: No private insurance or government coverage? You're likely eligible if income qualifies. - **Underinsured**: High copays/deductibles? Program may cover gaps, but **Medicare Part D patients are excluded**. - **No dual eligibility** with certain plans—verify during application. If insured, check EYLEA4U's reimbursement support for copay assistance instead. ## Step-by-Step Application Process 1. **Get a prescription**: Ask your eye doctor to confirm EYLEA is right for you. 2. **Check eligibility**: Call (855) 395-3248 or visit https://www.eylea4ueportal.com/ to pre-screen. 3. **Gather documents**: - Completed enrollment form (download from portal). - Proof of income (tax return, pay stubs, W-2s). - Proof of residency (utility bill, ID). - Physician-completed section (doctor submits prescription details). 4. **Submit application**: Online at https://www.eylea4ueportal.com/, mail, or fax. Physician often handles submission. 5. **Wait for approval**: Processing varies (weeks typical—see FAQ for details). 6. **Receive medication**: Shipped free to your home or doctor's office. **Tip**: Apply early—supply chain issues can delay. ## Timeline and Delivery - **Processing**: 2-4 weeks typically, but call for status. - **Delivery**: Free shipping to patient or physician office. Track via portal. - **Reauthorization**: Required periodically (e.g., annually)—doctor resubmits. ## Alternatives if Denied or Ineligible - **Biosimilars**: Aflibercept biosimilars expected 2026-2027—cheaper versions may lower costs. - **Other programs**: NeedyMeds, RxAssist, or PAN Foundation for eye conditions. - **Copay cards**: EYLEA4U reimbursement support for insured patients. - **State programs**: Check your state's pharmaceutical assistance. - **Generic VEGF inhibitors**: Discuss with doctor (none exact yet). ## Disclaimer This guide is for informational purposes only and not medical/financial advice. Eligibility, terms, and availability can change—**contact EYLEA4U at (855) 395-3248 or https://www.eylea4ueportal.com/ for latest details**. Consult your doctor before starting/stopping EYLEA. Regeneron not liable for application errors. Word count: ~950.

Program information last verified: March 29, 2026