Eylea

Indicated For

Wet Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Diabetic Macular Edema (DME), Macular Edema following Retinal Vein Occlusion (RVO), Retinopathy of Prematurity (ROP)

About This Medication

# Getting Eylea (Aflibercept) at No Cost Through the Regeneron Patient Assistance Program ## Who Qualifies for the Regeneron Patient Assistance Program? If you cannot afford Eylea (aflibercept), the **Regeneron Patient Assistance Program** may be able to provide it to you at no cost. This program is designed for patients who are uninsured, underinsured, or on Medicare and struggling to cover their out-of-pocket costs. To give you a quick benchmark: if you live alone, your household income generally needs to be **$75,300 or less per year** to qualify. Your insurance status also matters — you must either have no insurance, have insurance that does not cover Eylea, or be a Medicare patient who cannot afford your cost-share. If you meet these basic criteria, you may be a strong candidate for this program. --- ## About Eylea (Aflibercept) Eylea (aflibercept) is an FDA-approved injection used to treat several serious eye conditions, including **Wet Age-Related Macular Degeneration (AMD), Diabetic Retinopathy (DR), Diabetic Macular Edema (DME), Macular Edema following Retinal Vein Occlusion (RVO), and Retinopathy of Prematurity (ROP)**. It belongs to a class of drugs called VEGF inhibitors and works by blocking a protein that can cause abnormal blood vessel growth in the eye. Eylea is a biologic medication, meaning it is complex to manufacture, which contributes to its high cost. Without insurance or financial assistance, a single injection can cost several thousand dollars, making ongoing treatment financially out of reach for many patients. --- ## Income Eligibility: Full Breakdown The Regeneron Patient Assistance Program uses income thresholds based on **500% of the 2025 Federal Poverty Level (FPL)**. Here is the full breakdown by household size: | Household Size | Max Annual Income | |---|---| | 1 person | $75,300 | | 2 persons | $102,200 | | 3 persons | $129,100 | | 4 persons | $156,000 | If your household has more than four people, the income limit increases with each additional member. If your income is slightly above the limit, you are not automatically disqualified — Regeneron also considers **financial hardship** on a case-by-case basis. It is worth applying even if you are close to the cutoff. Your income is typically verified using your **most recent federal tax return, W-2 forms, or three months of recent pay stubs**. If you receive Social Security benefits, a Social Security Award Letter is also accepted. Make sure the documents you submit reflect your current household income as accurately as possible, since the review is based on your actual financial situation. --- ## Insurance Requirements Explained Your insurance status plays a key role in whether you qualify. Here is how different situations are handled: - **If you are uninsured:** You are likely eligible. Not having any insurance coverage is one of the primary qualifying conditions for this program. - **If you have Medicare Part D:** You may still qualify. The Regeneron Patient Assistance Program makes an exception for Medicare patients who cannot afford their cost-share, which is not the case with all manufacturer assistance programs. - **If you have private insurance that does not fully cover Eylea:** You may qualify if your plan either excludes the drug entirely or leaves you with a cost-share you cannot afford. Coverage that is partial or that comes with a very high deductible may still meet the program's "underinsured" standard. - **If you have Medicaid:** Patients with full Medicaid coverage are generally not eligible for manufacturer assistance programs, since Medicaid is designed to cover most or all of your drug costs. Contact the program directly at **(855) 395-3248** if you have questions about your specific Medicaid plan. --- ## Step-by-Step: How to Apply Follow these steps to apply for the Regeneron Patient Assistance Program: 1. **Gather your documents before you start.** You will need: a valid Eylea prescription from your doctor, proof of household income (tax return, W-2, pay stubs, or Social Security Award Letter), and your insurance information if applicable. 2. **Choose your application method.** You can apply online, by phone, or by fax. - **Online:** Visit [https://www.regeneronhealthcaresolutions.com/eylea](https://www.regeneronhealthcaresolutions.com/eylea) to complete a digital application. - **Phone:** Call **(855) 395-3248** to apply with a program representative or ask questions about your eligibility. - **Fax:** Submit a completed application by fax to **(844) 939-5324**. 3. **Complete the application with your prescriber.** Both you and your doctor must sign the application. Your prescriber's office can often help coordinate this, and many are familiar with the process. 4. **Submit your income documents** along with the signed application. Make sure all documents are legible and current. 5. **Wait for a determination.** Processing typically takes **2–3 business days** after Regeneron receives your complete application. 6. **Your prescriber's office will be notified** of the decision. If approved, medication is shipped directly to your prescriber's office, not your home. 7. **Schedule your injection appointment** as you normally would. Your doctor's office will have the medication ready when you arrive. --- ## What to Expect: Timeline and Delivery Once you submit a complete application, Regeneron typically processes it within **2–3 business days**. You or your prescriber's office will receive confirmation of approval. Eylea is **shipped directly to your prescriber**, so you do not need to pick it up at a pharmacy or make any separate arrangements. Simply attend your scheduled injection appointment as usual. To keep receiving Eylea at no cost, you will need to **reauthorize your enrollment once a year**. Regeneron will generally prompt your prescriber when it is time to renew. Be prepared to submit updated income documentation at that time to confirm you still meet the eligibility requirements. --- ## Alternatives If You Don't Qualify If you do not qualify for the Regeneron Patient Assistance Program, there are still options worth exploring: 1. **Biosimilar alternatives:** Two FDA-approved biosimilars to Eylea are available — **Opuviz (aflibercept-yszy)** and **Yesafili (aflibercept-jbvf)**. These may cost less and have their own assistance programs. Ask your doctor whether a biosimilar is appropriate for your condition. 2. **Savings card for insured patients:** If you have commercial insurance, Regeneron offers a **copay card** that may reduce your out-of-pocket costs. You can access it at [https://www.eylea.us/copay-card](https://www.eylea.us/copay-card). 3. **State Pharmaceutical Assistance Programs (SPAPs):** Many states offer their own drug assistance programs, especially for seniors and people with disabilities. Contact your state's department of health or aging to find out what is available in your area. 4. **NeedyMeds.org:** This free online database lists hundreds of patient assistance programs by drug name, condition, or manufacturer. Visit [NeedyMeds.org](https://www.needymeds.org) to search for additional resources. --- > *This guide is for informational purposes only and does not constitute medical or legal advice. Eligibility determinations are made solely by Regeneron. Program terms may change — verify current requirements at [https://www.eylea.us/patient-resources/insurance-and-financial-assistance](https://www.eylea.us/patient-resources/insurance-and-financial-assistance) before applying.* ---

Program information last verified: February 27, 2026