Exondys 51

Indicated For

Duchenne muscular dystrophy

About This Medication

# SareptAssist Patient Guide: How to Get Exondys 51 at Low or No Cost ## About This Program The SareptAssist Patient Assistance Program is designed to help patients with Duchenne muscular dystrophy (DMD) access Exondys 51 (eteplirsen) when cost is a barrier to treatment. This program is managed by Sarepta Therapeutics, the manufacturer of Exondys 51, and can provide the medication at reduced or no cost for eligible patients. ## About Exondys 51 Exondys 51 is an FDA-approved antisense oligonucleotide medication used to treat Duchenne muscular dystrophy, a rare genetic condition that causes progressive muscle weakness and degeneration. Exondys 51 works by helping the body produce a form of the dystrophin protein, which is missing or defective in people with DMD. This medication is administered by intravenous infusion, typically on a weekly basis. It's designed to slow the progression of muscle weakness in eligible patients. ## Who Can Qualify? You may qualify for the SareptAssist program if you: - Have been diagnosed with Duchenne muscular dystrophy (DMD) by a healthcare provider - Are currently uninsured or underinsured (meaning your insurance doesn't cover Exondys 51 or you have high out-of-pocket costs) - Meet the income eligibility requirements based on your household size - Are a U.S. resident The program is designed to help patients at all income levels, with flexibility for those who demonstrate financial need. ## Income Eligibility While specific income thresholds vary based on individual circumstances, the SareptAssist program considers household size and income when determining eligibility. The program uses a sliding scale approach, which means: | Household Size | General Income Range* | |---|---| | 1 person | Varies | | 2 people | Varies | | 3 people | Varies | | 4 people | Varies | | 5+ people | Varies | *Income thresholds are flexible and reviewed on a case-by-case basis. Even if your income is above certain guidelines, you may still qualify based on your specific financial situation, including medical expenses, debt, and other factors. **Contact the program directly at (888) 727-3782 to discuss your specific financial situation—many patients who think they won't qualify actually do.** ## Insurance Requirements The SareptAssist program is available for: - **Uninsured patients**: Those with no health insurance coverage - **Underinsured patients**: Those with insurance that doesn't cover Exondys 51 or requires high copayments, coinsurance, or deductibles If you have Medicare, Medicaid, or commercial insurance, you may still qualify for assistance with copayments and coinsurance costs. Contact the program to discuss your specific insurance situation. ## How to Apply: Step-by-Step Instructions ### Step 1: Gather Required Documents Before applying, collect the following documents: - **SareptAssist START Form** (or Sarepta Gene Therapy Enrollment Form if applicable), completed by your healthcare provider - **FDA-approved diagnosis confirmation** from your doctor's office (a letter confirming your DMD diagnosis) - **Proof of income** (recent tax return, pay stubs, or benefit statements) - **Proof of insurance status** (insurance card, denial letter, or documentation showing you're uninsured) - **Identification** (copy of driver's license or state ID) ### Step 2: Work with Your Healthcare Provider Contact your doctor's office and ask them to complete the **SareptAssist START Form**. This form requires your healthcare provider's signature and confirmation of your DMD diagnosis. Your provider's office can: - Complete the form during your visit - Submit it directly to the program on your behalf - Fax it to the program - Give you a completed copy to submit yourself ### Step 3: Submit Your Application You have multiple ways to submit your application: **Online**: Visit the program website at https://www.sarepta.com/sareptassist and submit your application through their secure online portal. **By Phone**: Call the SareptAssist program at **(888) 727-3782** to discuss your situation and submit information verbally. Program coordinators can guide you through the application process and answer questions. **By Fax**: Send your completed forms and supporting documents to **(800) 621-5203**. Include a cover letter with your name, date of birth, and contact information. **By Mail**: Mail your application materials to the address provided on the START Form. ### Step 4: Wait for Approval Once your application is received, the SareptAssist team will review it. **The typical processing time is 4-8 weeks**. During this time: - The program may contact you or your healthcare provider if additional information is needed - You'll be notified by mail or phone of the outcome - If approved, you'll receive instructions on how to access your medication ## What Happens After Approval? Once approved, medication delivery varies by program option. You'll receive detailed instructions on: - How to receive your medication (home delivery, specialty pharmacy pickup, etc.) - How often you'll need to refill your prescription - Who to contact with questions about your medication - How your approval works with your healthcare provider **Important**: Keep the SareptAssist program updated if your address, phone number, or insurance status changes. ## What If Your Application Is Denied? If your application is denied, you have options: 1. **Ask why**: Request a specific reason for the denial. Common reasons include missing documents or income exceeding guidelines. 2. **Appeal**: Ask if you can submit additional information or appeal the decision. Circumstances can change, and new information may affect the outcome. 3. **Reapply**: If your situation changes (income decreases, insurance coverage changes), you can reapply. 4. **Explore alternatives**: Ask your healthcare provider or the program about other assistance options. ## Alternative Resources If the manufacturer program doesn't work for you, explore these options: - **Patient advocacy organizations**: The Muscular Dystrophy Association (MDA) and other DMD organizations may have additional resources - **State pharmaceutical assistance programs**: Your state may have programs to help with prescription costs - **Hospital financial assistance**: If Exondys 51 is administered at a hospital or infusion center, ask about their financial aid programs - **Disease-specific foundations**: Organizations focused on muscular dystrophy may offer additional support ## Important Information - **This program is free to use**—never pay fees to apply for patient assistance - **Privacy is protected**—your information is kept confidential - **No obligation**—applying doesn't obligate you to use the medication if approved - **This is not insurance**—this program supplements or replaces insurance coverage for eligible patients ## Contact Information **SareptAssist Patient Assistance Program** - **Phone**: (888) 727-3782 - **Fax**: (800) 621-5203 - **Website**: https://www.sarepta.com/sareptassist - **Hours**: Contact the program for available support hours ## Legal Disclaimer This guide provides general information about the SareptAssist Patient Assistance Program and is not a substitute for official program information. Eligibility requirements, income thresholds, and program benefits may change. For the most current and accurate information about the program, visit the official website or contact the program directly at the phone number listed above. Always consult with your healthcare provider about whether Exondys 51 is appropriate for your treatment plan.

Program information last verified: March 25, 2026