Entresto

Indicated For

HFrEF, HFpEF

About This Medication

# Novartis Patient Assistance Foundation Patient Guide: How to Get Entresto (sacubitril valsartan) at Low or No Cost Entresto (sacubitril/valsartan) is a prescription medication used to treat heart failure in adults and children. The **Novartis Patient Assistance Foundation (NPAF)** offers Entresto at no cost to eligible patients who are uninsured or underinsured and meet specific income guidelines[1][2][3]. This guide explains everything you need to know to apply and get support. ## About Entresto **Entresto** is a combination drug containing sacubitril (a neprilysin inhibitor) and valsartan (an angiotensin II receptor blocker). It helps reduce the risk of hospitalization and death in people with certain types of heart failure by relaxing blood vessels, reducing blood pressure, and easing the heart's workload. It's typically prescribed when other heart failure treatments aren't enough. Always follow your doctor's instructions for use, as it may cause side effects like low blood pressure, high potassium levels, or kidney issues. Discuss with your healthcare provider (HCP) if Entresto is right for you[1][3]. ## Who Qualifies for NPAF? To qualify for free Entresto through NPAF, you must: - Live in the United States or a U.S. territory. - Have limited or no prescription insurance coverage (uninsured or underinsured). - Meet income guidelines based on 400% of the Federal Poverty Level (FPL) or less. - Have a valid prescription from a licensed U.S. HCP for outpatient treatment. Medicare patients may qualify if they meet income guidelines and provide proof, such as Extra Help denial if required. NPAF does not cover patients with certain alternative funding insurance[1][2][3][5]. ## Income Eligibility Breakdown Eligibility is based on household income at or below **400% of the FPL**. Household size is determined by your tax return (Form 1040). Provide proof like the first two pages of your most recent 1040, W-2, 1099, pay stubs, or Social Security statements if you don't file taxes. Here's a table of approximate annual income thresholds (adjusts yearly; confirm current FPL at application): | Household Size | Max Annual Income | |---------------|-------------------| | 1 (Individual) | $30,000 | | 2 (Couple) | $40,500 | | 3 | $51,000 | | 4 | $61,500 | *Add about $10,500 per additional family member. These are estimates; visit www.PAP.Novartis.com for exact figures for Entresto[1][2][5].* ## Insurance Requirements - **Uninsured**: No prescription coverage? You're likely eligible if income qualifies. - **Underinsured**: Limited coverage OK, but submit front/back copies of all insurance cards (primary, secondary, prescription). Include prior authorization (PA) or appeal denials if your insurance requires them. - **Medicare**: Possible if income-eligible; may need Extra Help denial proof. - Exclusions: No coverage if insurance ties to alternative funding programs that adjust based on PAP enrollment[1][2][3]. ## Step-by-Step Application Process 1. **Check Eligibility**: Go to www.PAP.Novartis.com or call (800) 277-2254 (Mon-Fri, 9am-6pm EST) to confirm Entresto qualifies and review your situation[2][3][4]. 2. **Gather Documents**: - Proof of income (e.g., tax return pages 1-2). - Proof of residency (e.g., utility bill). - Valid prescription for Entresto. - Proof of insurance status (cards front/back; PA denials if applicable). - Patient authorization signature[1][2][5]. 3. **Complete the Application**: - Download from https://www.patientassistance.novartis.com/application or PAP.Novartis.com. - Fill patient section (personal info, income, insurance, authorization). - Have your HCP complete their section (diagnosis, prescription, authorization). - Ensure everything is complete—missing info causes delays or denial[1][2][4]. 4. **Submit**: - **Online**: Via application portal. - **Phone**: (800) 277-2254 for help. - **Fax**: 1-855-817-2711. - **Mail**: Novartis Patient Assistance Foundation, PO Box 2529, Columbus, OH 43216 (or current address on form)[1][3][5]. Applications must be accurate; incomplete ones are rejected[1][2]. ## Timeline and Delivery - **Processing**: 2-4 weeks. You'll get a letter (and text if opted in) with next steps if more info needed, or final decision[3]. - **Approval**: Medication shipped free directly to you (not pharmacy). - **Duration**: Typically 1 year; reauthorization required annually with updated docs[1][3][8]. ## Alternatives if Denied - Review denial letter for reasons (e.g., income too high, incomplete app). - Resubmit with corrections. - Contact NPAF at (800) 277-2254 for guidance. - Explore other options: Novartis co-pay programs (if insured), state assistance, generic alternatives (none for Entresto currently), or RxHope.org for more PAPs. - No biosimilars available[3][5][6]. ## Refills and Reauthorization Approved patients get refills shipped. **Reauthorization** is required yearly—submit new app with updated income/insurance proof before supply ends[1][8]. ## Important Disclaimer This guide is for informational purposes based on available program details as of latest updates. Eligibility, guidelines, and processes can change; always verify at www.PAP.Novartis.com or by calling (800) 277-2254. NPAF reserves the right to modify/discontinue the program. Not legal/medical advice—consult your doctor and review full terms. Income thresholds approximate 400% FPL; actuals vary by year/location. Novartis not liable for application errors[1][2][3]. (Word count: 1028)

Program information last verified: March 30, 2026