ENSPRYNG

Indicated For

Neuromyelitis optica spectrum disorder (NMOSD)

About This Medication

# Genentech Patient Foundation and ENSPRYNG Co-pay Program Patient Guide: How to Get ENSPRYNG (satralizumab-mwge) at Low or No Cost ENSPRYNG (satralizumab-mwge) is a prescription medication used to treat certain autoimmune conditions like neuromyelitis optica spectrum disorder (NMOSD) in adults and children. The **Genentech Patient Foundation** and **ENSPRYNG Co-pay Program** help eligible patients access this important drug at low or no cost, depending on insurance status and financial need.[1][2][6] ## About ENSPRYNG and Why Assistance Matters **ENSPRYNG** is a biologic therapy given by subcutaneous injection, typically every 4 weeks after initial doses, to reduce relapses in NMOSD, a rare disease affecting the optic nerves and spinal cord. Treatment costs can exceed tens of thousands of dollars annually without help, making patient assistance programs essential for many.[6] Genentech, the manufacturer, offers two main programs: - **Genentech Patient Foundation**: Provides **free medication** for up to one year (renewable) to uninsured, underinsured, or insured patients with high out-of-pocket costs.[1][7] - **ENSPRYNG Co-pay Program**: Covers co-pays, deductibles, and co-insurance for commercially insured patients, reducing costs to as low as $0 per fill (up to program limits).[program details] These programs ensure continuity of care, especially since **reauthorization is required annually**.[program details][7] ## Who Qualifies? Eligibility varies by insurance and income. There are **no strict federal poverty level (FPL) cutoffs** listed; instead, requirements are tailored:[program details][6] - **Uninsured patients**: Qualify based on household income typically under $150,000 (exceptions apply) and financial need.[6] - **Insured patients**: Must have coverage for ENSPRYNG but face high costs, like an **out-of-pocket maximum over 7.5% of yearly income**.[6] - **Commercially insured**: Eligible for co-pay help if not on government insurance.[program details] **Key exclusions**: Medicare patients generally do not qualify for the Foundation (co-pay programs have limits); patients in Accumulator/Maximizer plans or required to use AFP vendors are ineligible.[4][7] ## Income Eligibility Breakdown Income thresholds depend on insurance status, household size, and costs. Use this table as a guide (call for personalized check): | Category | Income Threshold | Additional Criteria | Examples | |----------|------------------|---------------------|----------| | **Uninsured** | Under $150,000/year* | Household size considered; financial hardship proof may be needed | Single person: ~$150K max; Family of 4: Adjusted lower[6][8] | | **Insured w/ Coverage** | Varies | Out-of-pocket max >7.5% of income | $50K income, $4K+ OOP max qualifies[6] | | **Commercial Insurance (Co-pay)** | No strict limit | Financial concerns; not Medicare/Medicaid | High deductibles/co-insurance[program details] | *Exceptions apply. Confirm via (888) 941-3331 or online tool.[2][9] Household includes all living with you.[5][8] ## Insurance Requirements - **Uninsured**: Primary option for Foundation free drug.[1] - **Underinsured/Insured without ENSPRYNG coverage**: Foundation help if costs unaffordable.[6] - **Commercially insured**: Co-pay program for cost-sharing; Foundation if OOP too high.[program details][4] - **Medicare/Medicaid**: Limited; no Foundation for Medicare. Check co-pay options separately.[4][7] - **No citizenship required**; U.S. residents treated by U.S. physicians qualify.[6] ## Step-by-Step Application Process Applications are **multiple methods**; both **Patient Consent Form** and **Prescriber Foundation Form** are **required**.[1][6] 1. **Check eligibility**: Use online tool at gene.com/patients/patient-foundation/see-if-you-qualify or call (888) 941-3331 (Mon-Fri, 6am-5pm PT).[2][9] 2. **Gather info**: Household size, income, insurance details, deductible/OOP max.[5][8] 3. **Complete forms**: - **Patient**: Fill Patient Consent Form (English/Spanish) online or print.[1][5] - **Doctor**: Completes Prescriber Foundation Form.[6] 4. **Submit together**: | Method | Details | |--------|---------| | **Online** | eSubmit or My Patient Solutions (HCP account).[1][3] | | **Phone** | (844) 677-7964 or (888) 941-3331.[program details][2] | | **Fax** | 833-999-4363.[1][6] | | **Text** | Photo to 650-877-1111.[1] | | **Website** | enspryng.com/financial-support/apply.html.[program details] | 5. **Wait for contact**: Processed in ~5 business days; office/patient notified of outcome.[1][7] **No proof of income/appeals needed upfront**; submit while appealing denials.[4] ## Timeline and Delivery - **Processing**: 5 business days after both forms received.[1] - **Approval notice**: Phone contact to prescriber/patient.[1][8] - **Delivery**: Shipped free to **patient's home, participating pharmacy, or doctor's office**.[program details][5] - **Duration**: 1 year free meds; **reauthorization required** annually or upon insurance changes.[program details][7] - **Refills**: Automatic if eligible; reverify yearly.[7] ## Alternatives if Denied - **Appeal denial** with doctor (no proof needed for initial app).[4] - **Other programs**: Genentech Access Solutions for benefits check; state assistance; patient access networks (PAN Foundation, etc.).[2] - **Co-pay card**: If commercial insurance qualifies.[program details] - **Biosimilars**: None currently for ENSPRYNG.[program details] - **Call Foundation Specialist** for local resources.[2] ## Important Disclaimer This guide is for informational purposes based on available program details as of latest updates. Eligibility, terms, and availability can change; always verify with Genentech at (888) 941-3331 or official sites. Not medical/financial advice—consult your doctor and advisor. Genentech reserves rights to modify/terminate programs. Medicare patients: Federal law prohibits coverage of co-pays in some cases.[1][2][4]

Program information last verified: March 30, 2026