Daybue

Indicated For

Rett syndrome

About This Medication

# Acadia Connect Patient Assistance Program Guide: How to Get Daybue at Low or No Cost ## About This Program The Acadia Connect Patient Assistance Program is designed to help patients with Rett syndrome access Daybue (trofinetide) at little to no cost if they cannot afford their medication. Daybue is a prescription treatment specifically approved for Rett syndrome, a rare neurological disorder that affects girls and young women. This guide will walk you through the entire process of applying for assistance. ## What is Daybue? Daybue (trofinetide) is a medication developed by Acadia Pharmaceuticals to treat symptoms of Rett syndrome. Rett syndrome is a rare genetic neurological disorder that typically appears in infancy and can cause significant challenges with movement, communication, and behavior. Daybue is designed to help improve symptoms and functioning in patients with this condition. Your doctor can explain how Daybue may benefit your specific situation. ## Who Can Apply? You may qualify for the Acadia Connect Patient Assistance Program if you: - Have a valid prescription for Daybue from your healthcare provider - Are a U.S. resident - Are uninsured or underinsured (your insurance does not cover Daybue) - Meet the income eligibility requirements based on your household size - Are willing to complete the enrollment process and reauthorization as needed ## Income Eligibility Guidelines Your household income must fall within acceptable limits. While exact income thresholds vary based on individual circumstances, here is a general reference table: | Household Size | Approximate Maximum Income | |---|---| | 1 person | Varies by state and circumstance | | 2 people | Varies by state and circumstance | | 3 people | Varies by state and circumstance | | 4 people | Varies by state and circumstance | | 5+ people | Varies by state and circumstance | **Note:** Income limits are flexible and take into account individual circumstances. If you're unsure whether you qualify, apply anyway—the program will determine your eligibility during review. ## Insurance Requirements This program is available for patients who are: - **Uninsured:** You have no health insurance coverage - **Underinsured:** You have insurance, but it does not cover Daybue If you have insurance that covers Daybue, you may still qualify for a copay assistance program or savings card. Check the manufacturer website at https://www.acadiaconnect.com/daybue/caregivers/resources for additional savings options. ## How to Apply: Step-by-Step Instructions ### Step 1: Get Your Prescription Your healthcare provider must write a prescription for Daybue. If you don't have a doctor, contact the program at (844) 737-2223 to discuss options for obtaining medical evaluation and a prescription. ### Step 2: Gather Required Documents You will need: - Your prescription for Daybue from your doctor - The completed Enrollment Form (available from the program) - Proof of household income (recent tax return, pay stubs, or other documentation) - Proof of U.S. residency if applicable ### Step 3: Complete the Enrollment Form The Enrollment Form asks for basic information about you, your household, and your financial situation. You can obtain this form by: - Visiting https://www.acadiaconnect.com/daybue/caregivers/resources - Calling (844) 737-2223 - Asking your healthcare provider's office Fill out the form completely and accurately. This helps the program determine your eligibility quickly. ### Step 4: Submit Your Application You have multiple ways to apply: **By Phone:** Call (844) 737-2223. A program representative can answer questions and help you submit your information over the phone. **By Fax:** Fax your completed Enrollment Form and prescription to (888) 385-2748. **Online:** Visit https://www.acadiaconnect.com/daybue/caregivers/resources to apply online. **By Mail:** Send documents to the address provided by the program when you call or visit the website. ### Step 5: Wait for Approval The program typically processes applications within **4-8 weeks**. You will be notified once a decision has been made. ### Step 6: Receive Your Medication Once approved, your Daybue will be shipped directly to you through **AnovoRx Specialty Pharmacy**. You will not need to pick it up at a regular pharmacy. The specialty pharmacy will coordinate delivery to your home. ## Timeline and What to Expect - **Application submission:** Same day or within 1-2 business days - **Processing time:** Typically 4-8 weeks - **Notification:** You'll receive approval or denial in writing - **First shipment:** Usually arrives 1-2 weeks after approval - **Ongoing delivery:** Your medication will be refilled and shipped on a regular schedule ## Reauthorization Your assistance is not permanent. You will need to **reauthorize** periodically to continue receiving Daybue through this program. The program will notify you when reauthorization is needed (usually annually). You'll need to update your income information and enrollment status at that time. ## Copay Assistance and Savings Cards In addition to the patient assistance program, Acadia may offer a **savings card** if you have insurance. Even if your insurance doesn't cover Daybue, a savings card can reduce your out-of-pocket costs. Visit the manufacturer website to learn more: https://www.acadiaconnect.com/daybue/caregivers/resources ## What If Your Application Is Denied? If you don't qualify for the Acadia Connect program, you have options: 1. **Ask why you were denied.** The program will explain the reason. You may be able to reapply if your circumstances change. 2. **Explore other assistance.** Check with your state Medicaid program, state pharmaceutical assistance programs, or nonprofit organizations that help patients with rare diseases. 3. **Contact patient advocacy groups.** Organizations focused on Rett syndrome may have additional resources or funding. 4. **Discuss payment plans with your pharmacy.** AnovoRx Specialty Pharmacy may offer payment options. ## Important Reminders - **Keep your prescription valid.** You'll need an active prescription from your doctor to receive medication. - **Update contact information.** Tell the program if your address, phone number, or insurance changes. - **Don't skip doses.** If there's a gap in your assistance, contact the program immediately to discuss options. - **Ask questions.** The Acadia Connect team is available to help. Call (844) 737-2223 anytime. ## Contact Information **Acadia Connect Patient Assistance Program** - **Phone:** (844) 737-2223 - **Fax:** (888) 385-2748 - **Website:** https://www.acadiaconnect.com/daybue/caregivers/resources ## Legal Disclaimer This guide provides general information about the Acadia Connect Patient Assistance Program for Daybue (trofinetide). Program eligibility, requirements, and benefits may change without notice. For the most current and complete information, visit the official program website or call the program directly. This guide is not a guarantee of assistance or approval. Actual eligibility and benefits are determined by the program based on individual circumstances. Always consult with your healthcare provider about treatment options and speak with the program directly for specific questions about your application.

Program information last verified: March 25, 2026