Cystadane

Indicated For

Homocystinuria

About This Medication

# Cystadane Patient Assistance Program Patient Guide: How to Get Cystadane at Low or No Cost Cystadane (betaine anhydrous for oral solution) is a prescription medication used to treat homocystinuria, a rare genetic disorder that causes high levels of homocysteine in the blood. The **Cystadane Patient Assistance Program (PAP)**, offered by **Recordati Rare Diseases Inc.**, helps eligible uninsured or underinsured patients access this vital medication at low or no cost by providing 25-100% assistance for up to one year.[1][6] ## About Cystadane **Cystadane** helps lower elevated homocysteine levels in people with homocystinuria, a condition affecting how the body processes certain proteins. It's a powder mixed with water, juice, milk, formula, or food (4-6 ounces or 120-180 mL) and taken immediately. Store it at room temperature with the cap tightly closed to protect from moisture.[7][8] Unlike typical medications, Cystadane is **only available through a specialty pharmacy called Anovo**, which ships it directly to your home—not retail pharmacies.[2][8] Always follow your doctor's instructions for dosing, often starting at 6 grams daily (divided doses) and adjusted based on blood tests. Discuss diet, other medicines, and monitoring with your healthcare team, as Cystadane works best as part of a comprehensive plan.[2][7] ## Who Qualifies for the Program? This program targets patients facing financial barriers to Cystadane. Key eligibility criteria include: - **US residency** and a **medically appropriate diagnosis** (homocystinuria).[1] - **No prescription coverage** for Cystadane through insurance.[1][2][8] - Meeting **undisclosed income guidelines**—proof of income is required, but specific thresholds (e.g., Federal Poverty Level percentages) are not public.[1][5][6] - Assistance covers **25-100% of costs** for up to **one year**, with possible appeals for denials.[1][6] **Note:** A separate **Copay Assistance Program** exists for commercially insured patients, potentially reducing copays to $0. Contact Anovo to check which fits your situation.[3][4][8] ## Income Eligibility Breakdown Exact income limits are **not disclosed** by Recordati Rare Diseases Inc., so call for prescreening.[1][5] Here's a summary table based on available details: | Household Size | Income Threshold | FPL % | Notes | |---------------|------------------|-------|-------| | Individual | Not disclosed | Not specified | Proof of income required; medical expenses may factor in (unpublished).[1][5] | | Couple | Not disclosed | Not specified | Call (888) 487-4703 for prescreening.[1] | | Family of 3 | Not disclosed | Not specified | US residents only.[6] | | Family of 4 | Not disclosed | Not specified | Assistance 25-100% for 1 year.[1] | Since details are limited, **contact the program directly** at (888) 487-4703 (Monday-Friday, 8am-5pm CT) or through NORD (National Organization for Rare Disorders) for personalized guidance.[1][3] ## Insurance Requirements Patients **must have no prescription coverage** for Cystadane to qualify for the PAP.[1][2][8] If insured: - Use the **Copay Assistance Program** for copays/coinsurance (potentially $0 for commercial insurance).[3][4] - Anovo handles **benefit investigation** and **prior authorizations**.[3] Medicare or other plans may cover Cystadane; if not, PAP applies. Uninsured/underinsured individuals without coverage are primary candidates.[2][8] Anovo confirms eligibility and supports transitions (e.g., hospital to home).[4] ## Step-by-Step Application Process 1. **Talk to your doctor**: Develop a treatment plan. They complete and sign the **referral form/prescription** (CYSTADANE treatment form).[1][2][3] 2. **Fax the form**: Doctor faxes to 1-855-813-2039 (or call (888) 487-4703 for inpatient/home delivery).[3][4][8] 3. **Contact Anovo/NORD**: Call (888) 487-4703 to request an application mailed to you/doctor/social worker. Patients complete/sign their section and attach **proof of income**.[1][3] 4. **Submit application**: Fax or mail to NORD (e.g., 55 Kenosia Ave, Danbury, CT 06810; fax 203-349-3280).[1] Multiple methods available (phone, mail, fax).[1] 5. **Anovo processes**: They verify eligibility, ship to your home, and provide ongoing support (calls for refills).[2][3] **Required Documents**: - Referral form from healthcare provider. - Prescription. - Proof of income or insurance status.[1] Patients or providers can initiate.[1][6] ## Timeline and Delivery Processing time varies (not specified), but Anovo ships **directly to your home** monthly or up to 90-day supply.[2][3][6] Expect: - Quick start after faxed prescription.[2] - **Reauthorization required** annually or as needed.[1] - Return Anovo calls promptly for refills/continuity.[2] Negative decisions can be appealed.[1][6] ## Alternatives if Denied or Ineligible - **Copay Program**: For insured patients ($0 copay possible).[3][4] - **Biosimilar/Generic**: **Betaine Anhydrous for Oral Solution (Eton generic equivalent)**—discuss with doctor.[provided] - Other PAPs via RxHope/RxAssist or NORD.[1][5] - Appeal denial or reapply with updated info.[1] ## Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Eligibility, terms, and availability can change—**always verify with Recordati Rare Diseases Inc., Anovo at (888) 487-4703, or your healthcare provider**. Not medical/financial advice. Consult professionals for personalized guidance. Program run partly through NORD.[1][2]

Program information last verified: March 30, 2026