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Oncology

Cyramza

Generic: ramucirumab

Manufacturer: Eli Lilly and Company  ·  Program:

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Eligibility Criteria

Insurance Requirement

Commercial insurance with co-pay or coinsurance (for savings card, not PAP)

Residency

US residency required

Program Information

Processing Time

2–8 weeks

Delivery Method

Varies by program

Application Method

Online

Indicated For

advanced or metastatic gastric or gastroesophageal junction adenocarcinoma, metastatic NSCLC, metastatic colorectal cancer

About This Medication

# Lilly Oncology Support Services Patient Guide: How to Get Cyramza (ramucirumab) at Low or No Cost Cyramza (ramucirumab) is an expensive oncology medication, but **Eli Lilly and Company** offers the **Lilly Oncology Infused Products Savings Card Program** through Lilly Support Services to help eligible commercially insured patients reduce out-of-pocket costs to as little as $25 per infusion. This patient-friendly guide explains eligibility, application steps, and more to help you access treatment affordably.[1][2] ## About Cyramza (ramucirumab) **Cyramza** is a prescription monoclonal antibody used to treat certain types of advanced cancers, including stomach (gastric) cancer, colorectal cancer, and non-small cell lung cancer (NSCLC). It works by blocking a protein called VEGFR2, which helps stop the growth of blood vessels that feed tumors, slowing cancer progression when combined with other chemotherapies.[1][2] Administered as an intravenous (IV) infusion in a doctor's office or clinic, Cyramza is typically given every 2 or 3 weeks, depending on your treatment plan. Without assistance, costs can exceed thousands per dose due to its specialty status. Lilly Support Services provides comprehensive help beyond just cost savings, including benefit verification, prior authorization support, and coordination with specialty pharmacies. This ensures smoother access to your therapy.[1] ## Who Qualifies for the Program? The primary program is the **Lilly Oncology Infused Products Savings Card**, designed for **commercially insured patients** facing co-pay or coinsurance burdens. Key eligibility criteria include:[2] - Prescription for Cyramza for an FDA-approved use. - Enrollment in a **commercial drug insurance plan** that covers Cyramza but requires co-pay or coinsurance. - **Not enrolled in government programs** like Medicare (Parts A, B, D, Advantage), Medicaid, Medigap, VA, TRICARE, DoD, or state assistance programs. - Age 18 or older and a U.S. or Puerto Rico resident. **Important:** This is **not a free drug patient assistance program (PAP)** for uninsured or low-income patients. Government beneficiaries are explicitly excluded.[2][3] If you're uninsured or underinsured, Lilly Support Services may guide you to other resources, but no traditional income-based PAP details are available from Eli Lilly for Cyramza.[1][4] ## Income Eligibility Breakdown The Savings Card program **does not use income thresholds**; eligibility hinges on commercial insurance status, not household income. There are no Federal Poverty Level (FPL) limits or family size considerations.[2] For context, third-party services like Prescription Hope claim to help obtain Cyramza for a flat $60/month fee for those earning under $200,000/year, but this is not Eli Lilly's program.[5] | Household Size | Income Threshold | Notes | |---------------|------------------|-------| | Individual | None | Based on commercial insurance only[2] | | Couple | None | Government insurance disqualifies[2] | | Family of 3 | None | No FPL requirements[2] | | Family of 4 | None | US/Puerto Rico residents only[2] | If income is a barrier and you lack commercial coverage, explore state Medicaid or independent foundations (see Alternatives section).[6] ## Insurance Requirements **Commercial insurance** is **required** for the Savings Card. Your plan must cover Cyramza, but you'll pay co-pay/coinsurance unless assisted. The program covers these costs **minus $25 per infusion**, up to **$25,000 annually** and monthly limits based on wholesale acquisition cost (WAC) plus fees.[2][3] **Medicare, Medicaid, and other government programs disqualify you**—no exceptions.[2] Contact Lilly at (800) 545-5979 to verify benefits before applying.[1] ## Step-by-Step Application Process 1. **Confirm Eligibility:** Discuss with your doctor to ensure Cyramza is prescribed for an FDA-approved indication. Verify your commercial insurance covers it.[2] 2. **Contact Lilly Support Services:** Call **(800) 545-5979** (1-800-LillyRx) Monday-Friday, 8 AM-6 PM ET, or visit LillyOncologySupportCenter.com. A support specialist will check benefits, explain options, and help with prior authorizations.[1] 3. **Get the Savings Card:** If eligible, activate the digital Savings Card online or via phone. Present it at your infusion center. No formal application form is needed for most patients—it's instant for qualified individuals.[2] 4. **Provide Prescription:** Your doctor submits the prescription to a specialty pharmacy or infusion site coordinated by Lilly.[1] 5. **Use at Infusion:** Show the card each visit. Savings apply automatically to co-pay/coinsurance.[2] No specific documents are listed as required beyond proof of commercial insurance and prescription, but have your insurance card ready.[1][2] ## Timeline and Delivery **Processing is rapid:** Savings Card activation is often immediate upon eligibility confirmation. Infusions proceed as scheduled by your oncologist, typically coordinated within days.[1] Delivery occurs via your healthcare provider's infusion center—no home delivery mentioned. Refills aren't applicable as it's per-dose coverage; re-present the card each time. Annual cap resets January 1.[2] Exact timelines vary; call for personalized estimates.[1] ## Alternatives if Denied or Ineligible - **Uninsured/Low-Income:** No Eli Lilly PAP confirmed for Cyramza. Try third-party services like Prescription Hope ($60/month flat fee, income < $200k) or RxAssist.org for updates.[4][5] - **Government Insured:** Explore PAN Foundation, Patient Advocate Foundation Co-Pay Relief (up to 400% FPL), or Good Days.[6][8] - **Other Manufacturer Options:** Call (866) 472-8663 for potential expanded Lilly programs.[7][9] - **General Resources:** NeedyMeds, state Medicaid, or PAN Foundation. Biosimilar alternatives: None listed.[6] If denied Savings Card, ask Lilly about other support like free trial offers or reimbursement help.[1] ## Disclaimer This guide is for informational purposes only and based on publicly available data as of 2026. Programs change; **always verify with Eli Lilly at (800) 545-5979**. Not medical or financial advice—consult your doctor and advisor. Eli Lilly reserves rights to modify/terminate programs. Eligibility not guaranteed.[1][2]

Program information last verified: March 30, 2026

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