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CRYSVITA

Generic: burosumab-twza

Manufacturer: Kyowa Kirin  ·  Program: Kyowa Kirin Cares

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Eligibility Criteria

Insurance Requirement

Uninsured, underinsured, or commercially insured patients eligible for different assistance tiers

Residency

United States resident (including US territories)

Program Information

Processing Time

2 business days

Delivery Method

Shipped to patient or physician office

Application Method

Multiple

Reauthorization

Required — annual

Typically Required Documents

ProvisionRX prepares and organizes all required documentation as part of your enrollment management. This list is provided for informational purposes.

  • Enrollment form
  • Insurance information
  • Prescription from healthcare provider

Indicated For

X-linked hypophosphatemia (XLH), Tumor-induced osteomalacia (TIO)

About This Medication

# Kyowa Kirin Cares Guide: Getting CRYSVITA at Low Cost ## What is CRYSVITA? CRYSVITA (burosumab-twza) is a prescription medication used to treat two rare bone diseases: - **X-linked hypophosphatemia (XLH)**: A genetic condition causing low phosphate levels and weak bones - **Tumor-induced osteomalacia (TIO)**: A condition where tumors cause severe bone softening This medication can be expensive, but Kyowa Kirin offers assistance to help you afford it. ## What is the Kyowa Kirin Cares Program? Kyowa Kirin Cares is a prescription assistance program (PAP) that helps eligible patients obtain CRYSVITA at reduced or no cost. The program serves patients with different insurance situations and varying income levels. ## Who Can Apply? You may be eligible if you: - Have been prescribed CRYSVITA by your healthcare provider - Are a U.S. resident - Meet specific income requirements (limits vary based on household size) - Have one of the following insurance situations: - **No insurance** (uninsured) - **Insufficient insurance coverage** (underinsured) - **Commercial insurance** through your employer or marketplace Income limits vary by household size and are adjusted annually. Contact the program directly at **(833) 552-2737** to learn your specific income threshold, or visit **https://www.kyowakirincares.com** for current guidelines. ## Insurance Eligibility Rules **Uninsured Patients**: You may qualify for free or reduced-cost medication if your household income falls below program limits. **Underinsured Patients**: If your insurance coverage is limited or leaves you with high out-of-pocket costs, you may be eligible for additional assistance. **Commercially Insured Patients**: Even if you have health insurance, you may qualify for help paying copays, coinsurance, or deductibles. The program offers a **savings card** that can reduce your costs at the pharmacy. ## Step-by-Step Application Process **Step 1: Gather Required Documents** - Completed enrollment form (available on the website or by phone) - Current insurance information (insurance card or proof of no insurance) - Recent prescription from your healthcare provider for CRYSVITA - Proof of household income (recent tax return, pay stub, or benefit statement) **Step 2: Submit Your Application** You can apply through multiple methods: - **Online**: Visit https://www.kyowakirincares.com and complete the application - **Phone**: Call (833) 552-2737 to speak with a representative who can guide you through the process - **By Mail**: Request an application form and mail completed documents to the address provided **Step 3: Wait for Approval** The program reviews your application and verifies your eligibility based on income and insurance status. Processing typically takes 5-10 business days, though this may vary. **Step 4: Receive Your Medication** Once approved, you'll receive your prescription assistance. Uninsured and underinsured patients may receive the medication free or at reduced cost. Commercially insured patients will receive their savings card to use at participating pharmacies. ## Timeline and Renewal **Initial Approval**: Most applications are processed within 5-10 business days after submission of all required documents. **Annual Reauthorization**: Your assistance must be renewed each year. The program will notify you when renewal is needed. Submit updated income and insurance information to maintain your benefits. ## Using Your Savings Card If you have commercial insurance, you'll receive a **savings card** at no cost. Present this card at your pharmacy when filling your CRYSVITA prescription. The card can reduce your copay or coinsurance amount, making the medication more affordable. ## What Happens If You're Denied? If your application is denied, you have options: - Contact the program to understand the reason for denial - Reapply if your circumstances change (income, insurance status) - Ask about alternative assistance programs or patient resources - Discuss financial hardship options with your healthcare provider ## Get Help Now **Phone**: (833) 552-2737 **Website**: https://www.kyowakirincares.com Program representatives are available to answer questions and help you through the application process. Don't let cost prevent you from accessing the medication you need.

Program information last verified: March 25, 2026

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