Cholbam

Indicated For

bile acid synthesis disorders, peroxisomal disorders including Zellweger spectrum disorders

About This Medication

# Mirum Patient Assistance Program (PAP) Patient Guide: How to Get Cholbam (cholic acid) at Low or No Cost Cholbam (cholic acid) capsules are a prescription medication used to treat rare bile acid synthesis disorders and peroxisomal disorders like cerebrotendinous xanthomatosis (CTX). The **Mirum Patient Assistance Program (PAP)** from Mirum Pharmaceuticals helps eligible patients—primarily those without insurance—access Cholbam at no cost by shipping it directly to their home. ## About Cholbam (cholic acid) **Cholbam** is an FDA-approved oral bile acid therapy for specific genetic conditions where the body cannot produce enough primary bile acids. It is indicated for: - Patients with bile acid synthesis disorders (BASDs) due to deficiencies in key enzymes, such as CYP27A1 (CTX), AMACR, or others. - Patients with peroxisomal disorders, including Zellweger spectrum disorders, who show jaundice or hepatobiliary issues. Prescribed as capsules taken by mouth, the dose is individualized (e.g., total daily mg split into doses). It helps restore bile acid levels, improve liver function, and manage symptoms like fat-soluble vitamin malabsorption or xanthoma buildup in CTX. Always take as directed by your doctor—typically with food—and report side effects like diarrhea or liver enzyme changes promptly.[1][5] This guide focuses on the **Mirum PAP**, which provides free medication for up to one year (renewable) to uninsured patients. Related programs like QuickStart (for insurance delays) and Copay Assistance (for insured patients) are available via the same Mirum Access Plus (MAP) hub.[6][9] ## Who Qualifies for Mirum PAP? The program targets **uninsured or underinsured patients** in the US or Puerto Rico under a licensed doctor's care. It's **needs-based** but specific income thresholds (e.g., Federal Poverty Level percentages) are not publicly detailed—eligibility is determined case-by-case.[1][8] Key qualifiers: - Diagnosed with a Cholbam-indicated condition (provide ICD-10 code, e.g., for BASD or CTX).[1] - No or limited insurance coverage; underinsured may qualify via MAP referral.[8] - Residency in US/Puerto Rico. - Prescription from an enrolled healthcare provider (HCP). **Medicare patients**: May not qualify directly for PAP (as it's for uninsured), but check MAP for copay help or alternatives—consult your doctor or call 1-855-676-4968.[7][9] ## Income Eligibility Breakdown Detailed income limits aren't specified in program materials, emphasizing flexibility for uninsured patients. Here's a summary table based on available info: | Household Size | Income Threshold | Notes | |---------------|------------------|-------| | Individual | Not specified | Case-by-case review; FPL-based likely but undisclosed. | | Couple | Not specified | Uninsured prioritized. | | Family of 3 | Not specified | Annual eligibility review. | | Family of 4+ | Not specified | Contact program for assessment. | **Notes**: Program offers free Cholbam for up to 1 year, with re-enrollment required. Proof of income/hardship may be requested during review.[7] Always verify current criteria by calling **1-855-676-4968** (Mon-Fri, 8am-8pm ET).[5][7] ## Insurance Requirements **Primary focus: Uninsured patients**. Provide proof of insurance status (e.g., no coverage letter). Underinsured patients can be referred through MAP for PAP consideration or other aid like QuickStart (15-day supplies during delays, up to 60 days) or Copay programs ($0-$10/fill for commercial insurance).[6][8][9] - **Commercially insured**: Use Copay Assistance via MAP. - **Medicare/Medicaid**: Limited PAP access; explore MAP benefits or state programs. - Include insurance card (front/back) if any coverage exists.[1] ## Step-by-Step Application Process Your **HCP must initiate enrollment**—patients cannot apply alone. Here's how: 1. **Discuss with your doctor**: Confirm Cholbam prescription and urgent needs (e.g., check Urgent Access box for 15-day starter if delays expected).[1][6] 2. **Complete forms**: Doctor fills Patient Enrollment Form with your info (name, DOB, address, diagnosis/ICD-10, dose, allergies, insurance/pharmacy benefits). Patient signs authorization for data sharing.[1][2] 3. **Gather documents**: - Insurance card (front/back) or proof of no insurance. - Patient demographics (from EMR). - Optional: Income proof if requested.[1] 4. **Submit by fax**: HCP faxes to **1-855-282-4884**. No online portal listed.[1][3] 5. **Enroll in MAP (optional but recommended)**: Patients text MIRUM to 47936 or call 1-855-676-4968 for support, tracking, reminders.[4][10] 6. **Follow up**: Call 1-855-676-4968 for status (Mon-Fri, 8am-8pm ET).[5] ## Timeline and Delivery - **Processing**: Not specified; Urgent Access gives 15-day supply in ~5 business days if barrier exists, extendable to 60 days.[1][6] - **Delivery**: Shipped free to your home via Eversana (MAP pharmacy).[4][7] - **Refills**: Reauthorization required annually or per approval; HCP resubmits form.[7] Expect 94%+ insurance approvals in related programs, but PAP is for uninsured.[7] ## Alternatives if Denied - **Appeal**: Resubmit with more docs or doctor letter. - **MAP options**: QuickStart for delays, Copay for insured ($0-$10/fill).[6][9] - **Other aid**: RxAssist.org, state programs, or genetic testing support from Mirum.[5][8] - **Contact MAP**: 1-855-676-4968 for personalized guidance. ## Disclaimer This guide is for informational purposes based on publicly available data as of 2025. Program details can change—**always verify with Mirum at 1-855-676-4968 or your HCP**. Not medical advice; consult professionals for health decisions. Mirum disclaims liability for application outcomes. Word count: 942.

Program information last verified: March 25, 2026